Results 201 to 210 of about 23,915 (334)

Determination of Diketopiperazine Formation During the Solid‐Phase Synthesis of C‐Terminal Acid Peptides

open access: yesChemistry–Methods, EarlyView.
Diketopiperazine formation (DKP) is one of the most serious side reactions during peptide synthesis. An accurate method to determine the DKP formation in peptide synthesis on Wang resin is reported. Furthermore, the strategies to minimize this side reaction and side products lacking C‐terminal amino acids are described. Diketopiperazine formation (DKP)
Mani Kaushal   +7 more
wiley   +1 more source

Hypervalent iodine-mediated intramolecular alkene halocyclisation. [PDF]

open access: yesBeilstein J Org Chem
Bansal C   +3 more
europepmc   +1 more source

Durable Etched Silicon Powder‐Supported Palladium Catalyst for Continuous Flow Hydrogenation and Reductive Alkylation

open access: yesChemistry–Methods, EarlyView.
Etched silicon powder‐supported Pd is developed as a durable and efficient catalyst for continuous flow hydrogenation and reductive alkylation. This study develops a novel heterogeneous palladium catalyst immobilized on etched silicon powder, demonstrating high efficiency and long‐term stability under continuous flow conditions.
Zhenzhong Zhang   +4 more
wiley   +1 more source

The [3,3]‐Sigmatropic Allyl Cyanate–Isocyanate Rearrangement on Levoglucosenone Derivatives Stereoselectively Provides 4‐Deoxy‐4‐Aminosugars

open access: yesChemistry–Methods, EarlyView.
The Ichikawa rearrangement of allyl cyanates obtained in situ from levoglucosenone‐derived allyl carbamates allows the synthesis of unique 4‐deoxy‐4‐amino‐d‐allose derivatives with complete chirality transfer in a metal‐free three‐step, one‐pot manner.
Debora Pratesi   +6 more
wiley   +1 more source

Enantioselective Synthesis of Spirocyclic Nitrogen-Containing Heterocycles Catalyzed by an Iridium-Containing Cytochrome. [PDF]

open access: yesJ Am Chem Soc
Xu J   +7 more
europepmc   +1 more source

4‐Methylbenzhydryl Bromine Resin: Bridging the Gap between 2‐Chlorotrityl Chloride and Wang‐Type Resins for the Solid‐Phase Synthesis of C‐Terminal Acid Peptides

open access: yesChemistry–Methods, EarlyView.
Methylbenzhydryl bromine resin give good performance in specific condition copared to wang and 2‐chlorotrityl chloride resin. Over the last year, peptides have been consolidated as an important class of biomolecules, receiving increased attention from the pharmaceutical, cosmetic, and food industries. Most peptides currently used in both industrial and
Hassan Gamal   +10 more
wiley   +1 more source

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