Results 211 to 220 of about 47,089 (385)

Efficient Synthesis of Cyclopropane-Fused Heterocycles with Bromoethylsulfonium Salt [PDF]

, 2013
Aggarwal, Artamonov, Basavaiah, Boger, Bornholdt, Catalan-Munoz, Chaplinski, de Carne-Carnavalet, Donohoe, Eckert, Feng, Fritz, Fritz, Fritz, Galeazzi, Gensini, Gomi, Gosselck, Gosselck, Greene, Hanessian, Hansch, Huang, Iwabuchi, Jeffery, Kamimura, Kasai, Kim, Kim, Kokotos, Krieter, Krow, Kulinkovich, Lin, Maeda, Mao, McGarrigle, McGarrigle, Meldrum, Miller, Namba, Nelson, Njoroge, Norris, Nunez, Ohno, Renslo, Sabbatini, Sasaki, Sattigeri, Schoepp, Shi, Takahashi, Tverezovsky, Unthank, Unthank, Van Zijl, Wiberg, Wirth, Xie, Xie, Xu, Yamanaka, Yar, Yar, Yar, Zhang   +66 more
core   +2 more sources

The Treatment of Phthisis by Guaiacolate of Piperidine [PDF]

BMJ, 1897
Arnold Chaplin, F. W. Tunnicliffe
openaire   +3 more sources

Coumarin‐Caged Nanoparticle for Light‐Driven Surface Modification

ChemMedChem, EarlyView.
Photo‐responsive nanoparticles (NPs) enable spatiotemporal control over drug delivery. Attachment of a photo‐labile protecting group (PPG) to cell‐penetrating peptide (CPP) effectively camouflages the positive charge of NPs. Light irradiation cleaves the PPG, exposing the CPP on the NP surface and thereby enhancing cellular uptake.
Jan Birringer, Johannes Konrad, Stephan Melchner, Marius Remmert, Achim Goepferich   +4 more
wiley   +1 more source

Regiodivergent α- and β-Functionalization of Saturated <i>N</i>-Heterocycles by Photocatalytic Oxidation. [PDF]

J Am Chem Soc
Rackl JW, Müller AF, Profyllidou A, Wennemers H.   +3 more
europepmc   +1 more source

Dual Targeting Approach Using 4‐Hydroxytamoxifen Neuropeptide Y Conjugates for Selective Addressing of Adipose Tissue

ChemMedChem, EarlyView.
The [F7,P34]‐pNPY based peptide‐drug conjugate targets the Y1 receptor and induces internalization. Once inside the cell, 4‐hydroxytamoxifen is cleaved from the peptide and is released into the cytosol, where it activates the estrogen receptor α. This dual‐targeting mechanism aims to promote body weight loss and offers a potential therapeutic strategy ...
Anna Kohler, Eva‐Maria Jülke, Luke C. Darveniza, Jan Stichel, Annette G. Beck‐Sickinger   +4 more
wiley   +1 more source

[Expression of Concern] Halofuginone induces the apoptosis of breast cancer cells and inhibits migration via downregulation of matrix metalloproteinase‑9. [PDF]

Int J Oncol
Jin ML, Park SY, Kim YH, Park G, Lee SJ.
europepmc   +1 more source

PHARMACOLOGICAL STUDIES OF 1-PHENACYL-2, 3-DIMETHYL-3-(3-HYDROXYPHENYL) PIPERIDINE HYDROCHLORIDE (TA-306), AN ANALGESIC AND ANTITUSSIVE AGENT

, 1968
Goro Hayashi, SEIIGHI NURIMOTO, YUZO NOGUGHI, Hiroshi Kugita, Yoshio KOWA   +4 more
openalex   +1 more source

N-(N4-Aryl-N1 piperazinylmethyl)-4-(4'-methoxyphenyl)- piperidine-2,6-diones : CNS Depressants [PDF]

, 1978
S. D. SAMANT, R. A. KULKARNI
openalex   +1 more source

New Structure Activity Relationship Insight into the Role of the C‐3 Extension on Rifamycin Antimycobacterial Activity

ChemMedChem, EarlyView.
Rifamycin analogues with variably functionalized C‐3 extensions provide new insight into the role of this region for MTb inhibitory activity. In addition to potentially optimizing target engagement, this region can also be used to modulate physicochemical properties, an important consideration for optimizing antimycobacterial activity.
Clinton G. L. Veale, Ewelina Smolarz, Aleksandra Leśniewska, Krystian Pyta, Piotr Przybylski   +4 more
wiley   +1 more source

Transaminase-Triggered Cascades for the Synthesis and Dynamic Kinetic Resolution of Chiral N-Heterocycles. [PDF]

Angew Chem Int Ed Engl
O'Connell A, Haarr MB, Ryan J, Xu X, Martin A, Smith SN, Elghobashi-Meinhardt N, Fleming P, Maciá B, Caprio V, O'Reilly E.   +10 more
europepmc   +1 more source