Results 231 to 240 of about 24,641 (321)

In vitro activity of cefepime/zidebactam against sulbactam/durlobactam-susceptible and -resistant Acinetobacter baumannii clinical isolates. [PDF]

J Antimicrob Chemother
Tascini C, Bianco G, Bonomo RA, Gaibani P.   +3 more
europepmc   +1 more source

Novel Nonimidazole Histamine H₃ Receptor Antagonists:  1-(4-(Phenoxymethyl)benzyl)piperidines and Related Compounds

, 2003
Tibor Mikó, Xavier Ligneau, Heinz H. Pertz, C. Robin Ganellin, Jean‐Michel Arrang, Jean‐Charles Schwartz, Walter Schunack, Holger Stark   +7 more
openalex   +1 more source

Design, Synthesis, and Structural Evolution of Pseudo‐Natural Product IDO1 Inhibitors and Degraders

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
The combination of bicyclic monoterpene‐ and pyrrolidine‐alkaloid fragments yields novel pseudo‐natural products. Biological characterization revealed that these iDegs are inhibitors and degraders of indoleamine‐2,3‐dioxygenase. Abstract Terpenoid alkaloids are derived from the fusion of structurally diverse terpenoid‐ and alkaloid moieties.
Xiu‐Fen Cheng, Belén Lucas, Philipp Lampe, Stefano Ugel, Suyuan Chen, Anke Unger, Matthias Bischoff, Soheila Rezaei Adariani, Kesava Reddy Naredla, Kamal Kumar, Annika Schmidt, Carsten Strohmann, Petra Janning, Raphael Gasper, María Lucas, Malte Gersch, Sonja Sievers, Vincenzo Bronte, Slava Ziegler, Herbert Waldmann   +19 more
wiley   +2 more sources

Challenges and Limitations of Sequential MET-TKI Therapy in METex14- Positive NSCLC With a Focus on Non-ILD Toxicities: A Case Report. [PDF]

Cancer Rep (Hoboken)
Nigi A, Kumasa T, Iwamoto K, Itani H, Kondou S, Uraki J.   +5 more
europepmc   +1 more source

Novel Hexahydrospiro[piperidine-4,1‘-pyrrolo[3,4-c]pyrroles]:  Highly Selective Small-Molecule Nociceptin/Orphanin FQ Receptor Agonists

, 2002
Sabine Kolczewski, Geo Adam, Andrea M. Cesura, François Jenck, Michael Hennig, Thomas Oberhauser, Sonia Poli, Felix Rössler, Stephan Röver, Jürgen Wichmann, Frank M. Dautzenberg   +10 more
openalex   +1 more source

Chemoenzymatic Synthesis of Chiral 1-Benzyl-5-(hydroxymethyl)- 2-piperidone Enabled by Lipase AK-Mediated Desymmetrization of Prochiral 1,3-Diol and Its Diacetate [PDF]

, 2016
Gallagher, Timothy, Judeh, Zaher M A, Siri Pamarthy, Varsha, Thinh Khong, Duc   +3 more
core   +1 more source

A new chiral heterocyclic 1,1-enediamine as a precursor to piperidines

ARKIVOC, 2003
Raymond C. F. Jones, Simon C. Hirst
doaj   +1 more source

A modular synthesis of azetidines from reactive triplet imine intermediates using an intermolecular aza Paternò-Büchi reaction. [PDF]

Nat Catal
Williams BA, Tilby MJ, Parker NA, Uehling MR, Hethcox JC, Kalyani D, Willis MC.   +6 more
europepmc   +1 more source

Antagonists of human CCR5 receptor containing 4-(pyrazolyl)piperidine side chains. Part 1: Discovery and SAR study of 4-pyrazolylpiperidine side chains

, 2004
Dong‐Ming Shen, Min Shu, Sander G. Mills, Kevin T. Chapman, Lorraine Malkowitz, Martin S. Springer, Sandra L. Gould, Julie A. DeMartino, Salvatore Siciliano, Gloria Y. Kwei, Anthony Carella, Gwen Carver, Karen Holmes, William A. Schleif, Renee Danzeisen, Daria J. Hazuda, Joseph Kessler, Janet Lineberger, Michael D. Miller, Emilio A. Emini   +19 more
openalex   +1 more source

Organic Psychosis due to Lung Cancer Metastasis Accompanied by Severe Psychiatric Symptoms Treated With Blonanserin Transdermal Patch: A Case Report and Literature Review. [PDF]

Neuropsychopharmacol Rep
Yamaguchi J, Sadahiro R, Wada S, Nishikawa E, Terada T, Nakahara R, Matsuoka H.   +6 more
europepmc   +1 more source