Results 31 to 40 of about 24,641 (321)

Study on Multi Drug Resistant Opportunistic Pathogens Obtained from Clinical Settings of Tamil Nadu for Developing Novel Alternative Therapeutics

Journal of Pure and Applied Microbiology, 2019
Opportunistic pathogens prevail in the hospital environment, and utensils are the root cause of severe nosocomial infection. These pathogens exhibit high antibiotic resistance due to constant exposure to drug therapy.
Rajendran Venkatasubramani, Thirumoorthy Viswanathan   +1 more
doaj   +1 more source

Intermolecular [3+3] ring expansion of aziridines to dehydropiperi-dines through the intermediacy of aziridinium ylides

Nature Communications, 2020
Traditional synthesis of stereodefined piperidines requires selective installation of functional groups that can lower efficiency and modularity. Here, the authors assemble stereochemically complex and highly substituted dehydropiperidines via an ...
Josephine Eshon, Kate A. Nicastri, Steven C. Schmid, William T. Raskopf, Ilia A. Guzei, Israel Fernández, Jennifer M. Schomaker   +6 more
doaj   +1 more source

Crystal structure of 4-bromo-2-[(E)-N-(2,2,6,6-tetramethylpiperidin-4-yl)carboximidoyl]phenol dihydrate

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title hydrate, C16H23BrN2O·2H2O, the organic molecule features a strong intramolecular O—H...N hydrogen bond. The piperidine ring, in addition, adopts a chair conformation with the exocyclic C—N bond in an equatorial orientation.
Joel T. Mague, Shaaban K. Mohamed, Mehmet Akkurt, Antar A. Abdelhamid, Mustafa R. Albayati   +4 more
doaj   +1 more source

Ring Expansion of Vinylaziridines through the Strain-Release Pericyclic Reaction: Recent Developments and Applications

Molecules, 2013
Recent syntheses of azetidines, pyrrolidines, piperidines and azepines through cycloaddition or sigmatropic rearrangements of vinylaziridines are described. Applications to natural product synthesis and mechanistic investigations are also summarized.
Yu Mi Heo, Seung-Mann Paek
doaj   +1 more source

Synthesis, biological evaluation and docking analysis of substituted piperidines and (2-methoxyphenyl)piperazines [PDF]

Journal of the Serbian Chemical Society, 2016
A series of sixteen novel substituted piperidines and (2-methoxyphenyl)piperazines were synthesized, starting from the key intermediates 1-(2-methoxyphenyl)-4-(piperidin-4-yl)piperazine and 1-(2-methoxyphenyl)-4-(piperidin-4-ylmethyl)piperazine.
Penjišević Jelena Z., Šukalović Vladimir V., Andrić Deana B., Roglić Goran M., Novaković Irena T., Šoškić Vukić, Kostić-Rajačić Slađana V.   +6 more
doaj   +1 more source

Synthesis and kinetic resolution of N-Boc-2-arylpiperidines [PDF]

, 2014
The chiral base n-BuLi/(-)-sparteine or n-BuLi/(+)-sparteine surrogate promotes kinetic resolution of N-Boc-2-arylpiperidines by asymmetric deprotonation. The enantioenriched starting material was recovered with yields 39-48% and ers up to 97:3.
Bailey, Barker, Becker, Beng, Beng, Binanzer, Coldham, Coldham, Cui, Daniele Leonori, Edward J. Cochrane, Faibish, Granander, Hardy, Harrison, Hesp, Horton, Hsieh, Hsieh, Iain Coldham, Kagan, Kessar, Krasnov, Kreituss, Li, Lorraine A. Hassall, Millet, O'Brien, Pellissier, Penning, Rutherford, Seel, Sheikh, Stead, Strohmann, Vo, Xiao, Xiao, Xiao, Zuo   +39 more
core   +1 more source

Highly functionalized piperidines: Free radical scavenging, anticancer activity, DNA interaction and correlation with biological activity

Journal of Advanced Research, 2018
Twenty-five piperidines were studied as potential radical scavengers and antitumor agents. Quantitative interaction of compounds with ctDNA using spectroscopic techniques was also evaluated.
Suvankar Das, Cristiane J. da Silva, Marina de M. Silva, Maria Dayanne de A. Dantas, Ângelo de Fátima, Ana Lúcia T. Góis Ruiz, Cleiton M. da Silva, João Ernesto de Carvalho, Josué C.C. Santos, Isis M. Figueiredo, Edeildo F. da Silva-Júnior, Thiago M. de Aquino, João X. de Araújo-Júnior, Goutam Brahmachari, Luzia Valentina Modolo   +14 more
doaj   +1 more source

Synthesis of tetrafluorinated piperidines from nitrones via a visible-light-promoted annelation reaction

Beilstein Journal of Organic Chemistry, 2020
A method for the one-step construction of 3,3,4,4-tetrafluorinated piperidines from nitrones and readily accessible tetrafluorinated iodobromobutane is described.
Vyacheslav I. Supranovich, Igor A. Dmitriev, Alexander D. Dilman   +2 more
doaj   +1 more source

Dialkyl Carbonates in the Green Synthesis of Heterocycles

Frontiers in Chemistry, 2019
This review focuses on the use of dialkyl carbonates (DACs) as green reagents and solvents for the synthesis of several 5- and 6-membered heterocycles including: tetrahydrofuran and furan systems, pyrrolidines, indolines, isoindolines, 1,4-dioxanes ...
Pietro Tundo, Pietro Tundo, Manuele Musolino, Fabio Aricò   +3 more
doaj   +1 more source

Piperidine-1-carboximidamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2012
In the title compound, C(6)H(13)N(3), the C=N and C-N bond lengths in the CN(3) unit are 1.3090 (17), and 1.3640 (17) (C-NH(2)) and 1.3773 (16) Å, indicating double- and single-bond character, respectively. The N-C-N angles are 116.82 (12), 119.08 (11) and 124.09 (11)°, showing a deviation of the CN(3) plane from an ideal trigonal-planar geometry.
openaire   +2 more sources