Results 81 to 90 of about 23,915 (334)
Transaminase triggered aza-Michael approach for the enantioselective synthesis of piperidine scaffolds [PDF]
, 2016 The expanding “toolbox” of biocatalysts opens new opportunities to redesign synthetic strategies to target molecules by incorporating a key enzymatic step into the synthesis.
Andrew Gomm +6 more
core +3 more sources
Ultrasensitive Detection of FKBP12 Using a Synthetic Receptor‐Functionalized QCM Nanoplatform
Advanced Sensor Research, EarlyView.A reusable nanosensor platform for ultralow FKBP12 detection in physiological fluids is presented. Combining a gold‐coated QCM with a custom‐designed receptor in a self‐assembled monolayer, the device achieves picomolar sensitivity and high selectivity.
Martina Tozzetti +8 more
wiley +1 more source
Influence of Organic Structure Directing Agent Isomer Distribution on the Synthesis of SSZ-39 [PDF]
, 2015 The aluminosilicate molecular sieve with the AEI framework topology (SSZ-39) is currently of great interest for use in a number of important applications such as exhaust gas NO_x reduction and the methanol-to-olefins reaction.
Davis, Mark E. +5 more
core +2 more sources
Advanced Science, EarlyView.WSGC peptide reverses drug resistance in GA by modulating the Notch signaling pathway and mitophagy at the molecular level. Abstract This study investigates the molecular mechanisms by which superparamagnetic iron oxide nanoparticles (SPIONs) loaded with the WSGC peptide (WSGC@FA@PEG/PEI‐SPIONs)—a 40‐amino acid polypeptide derived from apoC‐III ...
Dongjian Song +10 more
wiley +1 more source
BMC Pharmacology and Toxicology, 2018 Background Emergence of resistance to artemisinins and some of their combinations in chemotherapy of clinical malaria has intensified the search for novel safe efficacious antimalarial molecules.
Moses N. Ngemenya +5 more
doaj +1 more source
Dynamics and Catalytic Resolution of Selected Chiral Organolithiums [PDF]
, 2011 One of the most important developments of the last decade has been the emergence of new methods to dynamically resolve racemic organolithiums using stoichiometric amounts of the chiral ligand.
Beng, Timothy Kum
core +1 more source
Advanced Science, EarlyView.HOP, an innovative ICT‐based fluorescent probe, visualizes H2O2 in stressed neurons while locally releasing serotonin (5‐HT) for real‐time protein interaction mapping. Its unique tandem sensing and labeling strategy reveals 5‐HT's role under oxidative stress, offering a powerful tool for neurophysiological research and therapeutic discovery.
Yani Liu +9 more
wiley +1 more source
The EVA spectral descriptor [PDF]
, 2000 The EVA descriptor is derived from fundamental IR- and Raman range molecular vibrational frequencies. EVA is sensitive to 3D structure but has an advantage over field-based 3D-QSAR methods inasmuch as it is invariant to both translation and rotation of ...
Turner, D.B., Willett, P.
core +1 more source
De Novo Design of Specific Heterotrimeric Collagen‐Like Peptides via Genetic Algorithm
Advanced Science, EarlyView.GRACE is a computational algorithm producing peptide sequences that will reliably fold into composition and registration‐controlled collagen‐like triple helices with user‐specified thermal stability. Additionally, GRACE allows users to specify the inclusion of biologically relevant (or other) sequences to automatically create tailored triple helices ...
Thi H. Bui +5 more
wiley +1 more source