Results 61 to 70 of about 5,094 (194)
A molecular basis for selective antagonist destabilization of dopamine D3 receptor quaternary organization [PDF]
, 2017 The dopamine D3 receptor (D3R) is a molecular target for both first-generation and several recently-developed antipsychotic agents. Following stable expression of this mEGFP-tagged receptor, Spatial Intensity Distribution Analysis indicated that a ...
Caltabiano, Gianluigi +6 more
core +2 more sources
The role of dimerisation in the cellular trafficking of G-protein-coupled receptors [PDF]
, 2010 The concept that G-protein-coupled receptors can exist as homomeric and/or heteromeric complexes is now well established. Despite this, how dynamic such interactions are and if this may be modulated during receptor trafficking remain topics of debate ...
Milligan, Graeme
core +1 more source
Powikłania ze strony przewodu pokarmowego w trakcie leczenia klozapiną
Psychiatria i Psychologia Kliniczna, 2015 Klozapina jest ostateczną opcją terapeutyczną w przypadku pacjentów ze schizofrenią oporną na leczenie. Podczas terapii często występują działania niepożądane ze strony przewodu pokarmowego: ślinotok, zaparcia, niedrożność jelit, niewydolność wątroby ...
Adam Wysokiński
doaj +1 more source
Influence of Overnight Orthokeratology on Axial Elongation in Childhood Myopia [PDF]
, 2011 Purpose. This prospective study was conducted to assess the influence of overnight orthokeratology (OK) on axial elongation in children, with those wearing spectacles as controls.Methods.
Hiraoka Takahiro +5 more
core +1 more source
Muscle &Nerve, Volume 70, Issue 5, Page 937-943, November 2024.Abstract Introduction/Aims Multidisciplinary care for patients with amyotrophic lateral sclerosis (ALS) is recommended in international guidelines, but reaches its limits when immobility increases. This pilot project addresses this gap by delivering home‐based, specialized, multiprofessional support to ALS patients who are not able to attend outpatient
Sarah Kristina Bublitz +5 more
wiley +1 more source
Neural control of tumor immunity
The FEBS Journal, Volume 291, Issue 21, Page 4670-4679, November 2024.Cancers are innervated by sensory, sympathetic and/or parasympathetic nerves. Interactions between these nerves, cancer cells as well as immune cells regulate overall tumor progression. While this indicates that the peripheral nervous system could be a potential target for promoting anti‐tumor immune responses, the precise mechanisms underlying nerve ...
Burak Kizil +2 more
wiley +1 more source
Dealing With Clozapine-Induced Sialorrhea
European Psychiatry, 2022 Introduction Clozapine is the first atypical antipsychotic. It is used in refractory schizophrenia. It has a heavy side effect burden, including weight gain, dizziness, blurred vision, and sialorrhea.
J. Sá Couto +4 more
doaj +1 more source
Muscarinic Modulation of High Frequency Oscillations in Pedunculopontine Neurons [PDF]
, 2013 We previously reported that persistent application of the non-specific cholinergic agonist carbachol (CAR) increased the frequency of calcium channel-mediated oscillatory activity in pedunculopontine nucleus (PPN) neurons, which we identified as ...
Belen Goitia +5 more
core +2 more sources
Neural Influences on Tumor Progression Within the Central Nervous System
CNS Neuroscience &Therapeutics, Volume 30, Issue 10, October 2024.Neurons can establish connections with tumor cells via chemical or electrical synapses, regulating the progression of tumors in the central nervous system. In addition, they can also enhance tumor proliferation and the formation of neurogliomal synapses by secreting proteins into the tumor microenvironment through paracrine signaling.
Wenhao Lv, Yongjie Wang
wiley +1 more source
Journal of Neuroscience Research, Volume 102, Issue 3, March 2024.Diagram illustrating the innervation of basolateral amygdalar pyramidal projection neurons (PN) and parvalbumin‐expressing interneurons (PV) by cholinergic (ACh) and GABAergic neurons of the basal forebrain, including what is known about the distribution of muscarinic receptors (M1 and M2) expressed by these structures, as well as cortical and thalamic
Alexander Joseph McDonald
wiley +1 more source