Results 61 to 70 of about 5,364 (186)

Functional neuroanatomy of basal forebrain projections to the basolateral amygdala: Transmitters, receptors, and neuronal subpopulations

Journal of Neuroscience Research, Volume 102, Issue 3, March 2024.
Diagram illustrating the innervation of basolateral amygdalar pyramidal projection neurons (PN) and parvalbumin‐expressing interneurons (PV) by cholinergic (ACh) and GABAergic neurons of the basal forebrain, including what is known about the distribution of muscarinic receptors (M1 and M2) expressed by these structures, as well as cortical and thalamic
Alexander Joseph McDonald
wiley   +1 more source

Normal and Pathological Tau Uptake Mediated by M1/M3 Muscarinic Receptors Promotes Opposite Neuronal Changes

Frontiers in Cellular Neuroscience, 2019
The microtubule associated protein tau is mainly found in the cell’s cytosol but recently it was also shown in the extracellular space. In neurodegenerative diseases, like Alzheimer’s disease (AD), pathological tau spreads from neuron to neuron enhancing
Viktoriya Morozova, Viktoriya Morozova, Leah S. Cohen, Ali El-Hadi Makki, Alison Shur, Alison Shur, Guillermo Pilar, Abdeslem El Idrissi, Abdeslem El Idrissi, Alejandra D. Alonso, Alejandra D. Alonso   +10 more
doaj   +1 more source

Acetylcholine Receptor Stimulation Activates Protein Kinase C Mediated Internalization of the Dopamine Transporter

Frontiers in Cellular Neuroscience, 2021
The dopamine transporter (DAT) clears neurotransmitters from the extracellular space and serves as an important regulator of signal amplitude and duration at sites of dopamine release. Several different intracellular signaling pathways have been observed
Suzanne M. Underhill, Susan G. Amara
doaj   +1 more source

Autoantibodies against Submandibular Gland Muscarinic Cholinoceptor Subtypes in Primary Sjögren Syndrome

European Journal of Inflammation, 2005
Sjögren Syndrome (SS) is a chronic autoimmune disease characterized by parasympathetic exocrine gland dysfunction. Here, the involvement of submandibular gland muscarinic acetylcholine receptor (mAChR) M 4 subtype is proposed as an IgG target together ...
S. Reina, L. Sterin-Borda, B. Orman, E. Borda   +3 more
doaj   +1 more source

The Impact of Removal of Ovarian Hormones on Cholinergic Muscarinic Receptors: Examining Prepulse Inhibition and Receptor Binding

Brain Sciences, 2020
Ovarian hormones, such as estrogens and progesterone, are known to exert beneficial effects on cognition and some psychiatric disorders. The basis of these effects is not fully understood, but may involve altered cholinergic neurotransmission. This study
Sarah S. Ch’ng, Adam J. Walker, Madeleine McCarthy, Thien-Kim Le, Natalie Thomas, Andrew Gibbons, Madhara Udawela, Snezana Kusljic, Brian Dean, Andrea Gogos   +9 more
doaj   +1 more source

Effects of cholecystokinin-octapeptide and cerulein on ovine digestive motility under cholinergic blockade

European Journal of Biological Research, 2017
In sheep, contribution of cholinergic system to the control of gastrointestinal motility by cholecystokinin is unknown. Accordingly, in six non-fasted rams chronic experiments were conducted and the myoelectrical activity of abomasal antrum, duodenum and
Krzysztof W. Romański
doaj  

Behavioral effects of Bj-PRO-7a, a proline-rich oligopeptide from Bothrops jararaca venom [PDF]

Brazilian Journal of Medical and Biological Research
The heptapeptide Bj-PRO-7a, isolated and identified from Bothrops jararaca (Bj) venom, produces antihypertensive and other cardiovascular effects that are independent on angiotensin converting enzyme inhibition, possibly relying on cholinergic muscarinic
L.C. Turones, K.R. da Cruz, G. Camargo-Silva, L.L. Reis-Silva, D. Graziani, P.M. Ferreira, P.M. Galdino, G.R. Pedrino, R. Santos, E.A. Costa, D. Ianzer, C.H. Xavier   +11 more
doaj   +2 more sources

The Lower Urinary Tract Science Group Abstracts—ICI‐RS 2024

Neurourology and Urodynamics, Volume 44, Issue 3, Page 691-697, March 2025.
Christopher H. Fry, Andrew Gammie, Bahareh Vahabi, Faezeh A. Hassani, Karen D. McCloskey, Mathijs M. de Rijk, Pradeep Tyagi, Hikaru Hashitani, Michael Winder, Patrik Aronsson, Basu Chakrabarty   +10 more
wiley   +1 more source

On the Mechanisms Underlying Histamine Induction of Gastric Mucosal Lesions in Rats With Partial Gastric Vascular Occlusion

Journal of Pharmacological Sciences, 2003
Although it is well known that histamine induces gastric mucosal lesions in laboratory animals, the fundamental mechanisms remain unclear. In order to further analyze the vascular mechanisms underlying histamine-induced lesions, a new model was developed
Kikuko Amagase, Susumu Okabe
doaj   +1 more source

Muscarinic acetylcholine receptor M1 and M3 subtypes mediate acetylcholine-induced endothelium-independent vasodilatation in rat mesenteric arteries

Journal of Pharmacological Sciences, 2016
The present study investigated pharmacological characterizations of muscarinic acetylcholine receptor (AChR) subtypes involving ACh-induced endothelium-independent vasodilatation in rat mesenteric arteries.
Panot Tangsucharit, Shingo Takatori, Yoshito Zamami, Mitsuhiro Goda, Poungrat Pakdeechote, Hiromu Kawasaki, Fusako Takayama   +6 more
doaj   +1 more source