Results 71 to 80 of about 4,218 (200)
Muscarinic depolarization of layer II neurons of the parasubiculum. [PDF]
PLoS ONE, 2013 The parasubiculum (PaS) is a component of the hippocampal formation that sends its major output to layer II of the entorhinal cortex. The PaS receives strong cholinergic innervation from the basal forebrain that is likely to modulate neuronal ...
Stephen D Glasgow, C Andrew Chapman
doaj +1 more source
Frontiers in Cellular Neuroscience, 2019 The microtubule associated protein tau is mainly found in the cell’s cytosol but recently it was also shown in the extracellular space. In neurodegenerative diseases, like Alzheimer’s disease (AD), pathological tau spreads from neuron to neuron enhancing
Viktoriya Morozova +10 more
doaj +1 more source
European Journal of Biological Research, 2017 In sheep, contribution of cholinergic system to the control of gastrointestinal motility by cholecystokinin is unknown. Accordingly, in six non-fasted rams chronic experiments were conducted and the myoelectrical activity of abomasal antrum, duodenum and
Krzysztof W. Romański
doaj
European Journal of Inflammation, 2005 Sjögren Syndrome (SS) is a chronic autoimmune disease characterized by parasympathetic exocrine gland dysfunction. Here, the involvement of submandibular gland muscarinic acetylcholine receptor (mAChR) M 4 subtype is proposed as an IgG target together ...
S. Reina +3 more
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Bidirectional hebbian plasticity induced by low-frequency stimulationin basal dendrites of rat barrel cortex layer 5 pyramidal neurons [PDF]
, 2017 According to Hebb’s original hypothesis (Hebb,1949), synapses are reinforced when presynaptic activity triggers postsynaptic firing, resulting in long-term potentiation (LTP) of synaptic efficacy. Long-term depression (LTD) is a use-dependent decrease in
Barros-Zulaica, Natali +4 more
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Frontiers in Cellular Neuroscience, 2019 Cisplatin remains an indispensable drug for the systemic treatment of many solid tumors. However, a major dose-limiting side-effect is ototoxicity. In some scenarios, such as treatment of germ cell tumors or adjuvant therapy of non-small cell lung cancer,
Anke Tropitzsch +7 more
doaj +1 more source
Brain Sciences, 2020 Ovarian hormones, such as estrogens and progesterone, are known to exert beneficial effects on cognition and some psychiatric disorders. The basis of these effects is not fully understood, but may involve altered cholinergic neurotransmission. This study
Sarah S. Ch’ng +9 more
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Cholinergic regulation of mood: from basic and clinical studies to emerging therapeutics. [PDF]
, 2019 Mood disorders are highly prevalent and are the leading cause of disability worldwide. The neurobiological mechanisms underlying depression remain poorly understood, although theories regarding dysfunction within various neurotransmitter systems have ...
Dulawa, Stephanie C, Janowsky, David S
core
Identification of novel therapeutics for complex diseases from genome-wide association data [PDF]
, 2014 Background: Human genome sequencing has enabled the association of phenotypes with genetic loci, but our ability to effectively translate this data to the clinic has not kept pace.
Ballouz, S. +6 more
core +1 more source
The Lower Urinary Tract Science Group Abstracts—ICI‐RS 2024
Neurourology and Urodynamics, Volume 44, Issue 3, Page 691-697, March 2025.
Christopher H. Fry +10 more
wiley +1 more source