Results 81 to 90 of about 1,005 (173)

Comorbidity of obstructive sleep apnea and narcolepsy: A challenging diagnosis and complex management

Sleep Medicine: X
Introduction: Narcolepsy and obstructive sleep apnea syndrome (OSA) are relevant causes of excessive daytime sleepiness (EDS); although different for etiopathogenesis and symptoms, differential diagnosis is sometimes difficult, and guidelines are lacking
Silvia Miano, Leila Kheirandish-Gozal, Marco De Pieri   +2 more
doaj   +1 more source

Histamine H₃ Receptor Isoforms: Insights from Alternative Splicing to Functional Complexity

Biomolecules
Alternative splicing significantly enhances the diversity of the G protein-coupled receptor (GPCR) family, including the histamine H3 receptor (H3R).
Meichun Gao, Jasper F. Ooms, Rob Leurs, Henry F. Vischer   +3 more
doaj   +1 more source

Is Pitolisant Effective in Reducing Excessive Daytime Sleepiness and Cataplexy in Adults with Narcolepsy?

, 2019
Objective: The objective of this selective EBM review is to determine whether or not pitolisant is effective in reducing excessive daytime sleepiness and cataplexy in adults with narcolepsy.
Michael, Christina M
core  

A Review of Current and Future Pharmacologic Treatments for Narcolepsy

European Psychiatry
Introduction Narcolepsy is a rare but disabling neurological disorder involving disruption of the sleep-wake cycle that is often under- or misdiagnosed (Barateau L, et al. J Sleep Res. 2022;31(4):e13631).
P. Chue, J. Chue, M. Tate, A. Andreiev, A. Abba-Aji   +4 more
doaj   +1 more source

Treatment paradigms for cataplexy in narcolepsy: past, present, and future

Nature and Science of Sleep, 2015
Todd J Swick1–4 1Department of Neurology, University of Texas School of Medicine-Houston, Houston; 2The Sleep Center at North Cypress Medical Center, Cypress; 3Apnix Sleep Diagnostics, Houston; 4Neurology and Sleep Medicine Consultants, Houston, TX,
Swick TJ
doaj  

Wide implications of a trial on pitolisant for cataplexy [PDF]

The Lancet Neurology, 2017
openaire   +4 more sources

0613 Effects of Pitolisant on Nighttime Sleep [PDF]

Sleep, 2019
Ulf Kallweit, Annika Triller
openaire   +1 more source

Long-term efficacy and safety of pitolisant for residual sleepiness due to OSA

: Background In people with OSA, excessive daytime sleepiness is a prominent symptom and can persist despite adherence to CPAP, the first-line therapy for OSA.
Tamisier, Renaud, P\ue9pin, Jean-Louis, Causs\ue9, Christian, Dauvilliers, Yves, Lecomte, Isabelle, Attali, Val\ue9rie, Verbraecken, Johan, Lehert, Philippe, L\ue9vy, Patrick, Hedner, Jan   +9 more
core  

Pitolisant Improves Depressive Symptoms in CPAP-Treated Patients with Obstructive Sleep Apnea and Severe Residual Sleepiness: First 12-Month Clinical Experience. [PDF]

CNS Drugs
Caratozzolo D, Muscato G, Rizzo P, Gangemi C, Scionti A, Mancuso S, Vancheri C, Spicuzza L.   +7 more
europepmc   +1 more source

A proof-of-concept study of pitolisant for excessive daytime sleepiness in patients with Prader-Willi syndrome. [PDF]

J Clin Sleep Med
Revana A, Bhattacharjee R, Miller JL, Chidekel A, Khanna P, Ratnam S, Runyan G, Bauer E, Davis Rapchak K, Seiden D, Budur K, Dayno JM.   +11 more
europepmc   +1 more source