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The placebo effect is a fascinating phenomenon in clinical practice. Studies have shown that there is a significant placebo effect in a wide range of medical conditions including psychiatric disorders. This article looks at the background of the placebo effect, defines the common terms used, describes the various hypotheses that have been put forward ...
openaire +8 more sources
Objective: Predicting who will be a placebo responder is a prerequisite to maximize placebo effects in pain treatment and to minimize them in clinical trials. First evidence exists that genetics could affect placebo effects.
Katja Weimer+7 more
doaj +1 more source
Background There is increasing evidence suggesting that open-label placebo (OLP) is an effective treatment for several medical conditions defined by self-report.
Julia W. Haas+9 more
doaj +1 more source
Effects of creatine monohydrate supplementation on simulated soccer performance [PDF]
Purpose: To determine the effects of acute short-term creatine (Cr) supplementation on physical performance during a 90-min soccer-specific performance test. Methods: A double-blind, placebo-controlled experimental design was adopted during which 16 male
Abt, Grant+2 more
core +1 more source
Causal progress with imperfect placebo treatments and outcomes [PDF]
In the quest to make defensible causal claims from observational data, it is sometimes possible to leverage information from "placebo treatments" and "placebo outcomes". Existing approaches employing such information focus largely on point identification and assume (i) "perfect placebos", meaning placebo treatments have precisely zero effect on the ...
arxiv
Not a Placebo, but Is It Effective? [PDF]
Randomized, placebo-controlled studies are a rare commodity in interventional pain medicine. Pain Medicine , is therefore, pleased to publish such a study, in which Kappural et al. report their results of transdiscal biacuplasty for the treatment of chronic low back pain ⇓. Publication recognizes that a study was methodologically sound.
openaire +3 more sources
When the placebo effect is not an effect [PDF]
In this issue of the journal, Rosen et al. report the results of a survey of surgeons regarding placebo effects.1 In particular, they show that surgeons consider “non-specific” effects (including a...
openaire +4 more sources
Prophylactic use of carvedilol to prevent ventricular dysfunction in patients with cancer treated with doxorubicin [PDF]
Objective: Deterioration in ventricular function is often observed in patients treated with anthracyclines for cancer. There is a paucity of evidence on interventions that might provide cardio-protection.
Abrar, Mohammed Burhan+8 more
core +1 more source
The Role of Placebo Samples in Observational Studies [PDF]
In an observational study, it is common to leverage known null effect to detect bias. One such strategy is to set aside a placebo sample -- a subset of data immune from the hypothesized cause-and-effect relationship. Existence of an effect in the placebo sample raises concern of unmeasured confounding bias while absence of it corroborates the causal ...
arxiv
Chronic cough and esomeprazole: A double-blind placebo-controlled parallel study [PDF]
Background and objective: Gastro-oesophageal reflux has been implicated in the pathogenesis of chronic cough. Guidelines on management suggest a therapeutic trial of anti-reflux medication.
Beecher+41 more
core +1 more source