Results 11 to 20 of about 5,256,367 (214)

Predictors of placebo response in peripheral neuropathic pain: insights from pregabalin clinical trials

Journal of Pain Research, 2015
Roy Freeman,1 Birol Emir,2 Bruce Parsons2 1Autonomic and Peripheral Nerve Laboratory, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA; 2Pfizer Inc, New York, NY, USABackground: Greater understanding of factors associated ...
Freeman R, Emir B, Parsons B
doaj   +1 more source

Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data [PDF]

, 2021
The brain systems underlying placebo analgesia are insufficiently understood. Here we performed a systematic, participant-level meta-analysis of experimental functional neuroimaging studies of evoked pain under stimulus-intensity-matched placebo and ...
Leknes, S., Schenk, L., Benedetti, F., Zunhammer, M., Choi, J., Büchel, C., Kaptchuk, T., Müllner-Huber, A., Wagner, T., Kong, J., Wrobel, N., Ellingsen, D., Kirsch, I., Lamm, C., Lui, F., Schmid, J., Theysohn, N., Colloca, L., Tracey, I., Porro, C., Zeidan, F., Duzzi, D., Spisák, T., Kessner, S., Rütgen, M., Eippert, F. ; https://orcid.org/, Bingel, U., Elsenbruch, S., Geuter, S., Atlas, L.   +29 more
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Placebo effect of an inert gel on experimentally induced leg muscle pain. [PDF]

, 2010
Purpose: This study examined the therapeutic effects of an inert placebo gel on experimentally induced muscle pain in a sports therapy setting. It aimed to investigate the degree to which conditioned analgesia, coupled with an expectation of intervention,
Coleman, Damian A, Beedie, C., Leach, G., Foad, A., Hopker, James G.   +4 more
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Informed consent and placebo effects: a content analysis of information leaflets to identify what clinical trial participants are told about placebos [PDF]

, 2012
BackgroundPlacebo groups are used in randomised clinical trials (RCTs) to control for placebo effects, which can be large. Participants in trials can misunderstand written information particularly regarding technical aspects of trial design such as ...
Alison E. M. Adams (317941), George T. Lewith (317942), Kaptchuk, Ted J., Ted J Kaptchuk, Ted J. Kaptchuk (234474), Bishop Felicity L., Lewith George T., Adams, Alison E. M., Kaptchuk, Ted, Bishop, Felicity L., Felicity L. Bishop (317940), Adams Alison E. M., Alison E M Adams, Kaptchuk Ted J., Lewith, George, Lewith, George T., Felicity L Bishop, Adams, Alison E.M., George T Lewith   +18 more
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Placebo use in the United Kingdom: results from a national survey of primary care practitioners [PDF]

, 2013
Objectives: Surveys in various countries suggest 17% to 80% of doctors prescribe ‘placebos’ in routine practice, but prevalence of placebo use in UK primary care is unknown.Methods: We administered a web-based questionnaire to a representative sample of ...
Heneghan, C, Stevens, Sarah, Wolstenholme Jane, Hobbs, Richard, Stevens, S, Louhiala, Pekka, Sarah Stevens, Hemilä, Harri, Bishop, F.L, George Lewith, Hobbs F. D. Richard, Wolstenholme, Jane, Wolstenholme, J, Bishop, FL, Hobbs, F.D.R., Carl Heneghan, Stevens Sarah, Howick, Jeremy, Jeremy Howick, Lewith, George T., Felicity L Bishop, F D Richard Hobbs, Heneghan, C., Wolstenholme, J., Bishop Felicity L., Howick, J, Howick, J., Howick Jeremy, Heneghan Carl, Hobbs, FD, Lewith, G, Puustinen, Raimo, Lewith George, Jane Wolstenholme, Heneghan, Carl   +34 more
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Influence on study outcomes of an inpatient study by the behavior of the study staff (PINgPOng): study protocol for a randomized clinical trial

Trials, 2022
Background The placebo effect as the symptom improvement following inert treatments is a fixed component of RCTs to differentiate between specific effects of the tested pharmacological substance from other unspecific effects.
Martin Coenen, Ulrike Bingel, Matthias Zunhammer, Maria Soledad Berdaguer, Christine Fuhrmann, Rolf Fimmers, Jens Rengelshausen, Gunther Hartmann, Manfred Schedlowski, Christoph Coch   +9 more
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Antidepressants versus placebo for depression in primary care [PDF]

, 2009
Background Concern has been expressed about the relevance of secondary care studies to primary care patients specifically about the effectiveness of antidepressant medication.
Grant Blashki, Tim Kenealy, Blashki, Grant, Stephen MacGillivray, Kerse, Ngaire, Ngaire Kerse, Felicity A Goodyear-Smith, Fishman, Tana, Goodyear-Smith, Felicity A., MacGillivray, Stephen; id_orcid, Elley, C. Raina, C Raina Elley, Arroll, Bruce, Bruce Arroll, Tana Fishman, Kenealy, Tim   +15 more
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Placebo Economics: A Systematic Review About the Economic Potential of Utilizing the Placebo Effect

Frontiers in Psychiatry, 2019
Background: Recent research shows that placebo mechanisms can be utilized in ethical and legal ways such as in open-label conditions, when patients know that they receive placebos, and through psychological interventions aiming to optimize patients ...
Jens Hamberger, Jens Hamberger, Karin Meissner, Karin Meissner, Thilo Hinterberger, Thomas Loew, Katja Weimer   +6 more
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Placebo response and effect in randomized clinical trials: meta-research with focus on contextual effects

Trials, 2021
Background Contextual effects (i.e., placebo response) refer to all health changes resulting from administering an apparently inactive treatment. In a randomized clinical trial (RCT), the overall treatment effect (i.e., the post-treatment effect in the ...
Sigurlaug H. Hafliðadóttir, Carsten B. Juhl, Sabrina M. Nielsen, Marius Henriksen, Ian A. Harris, Henning Bliddal, Robin Christensen   +6 more
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Placebo-controlled pharmacological trials in child and adolescents with bipolar disorder manic episode (BPD-ME): Systematic review, meta-analysis and a meta-regression on placebo response (eng)

Klinik Psikiyatri Dergisi, 2020
Objective: Randomized placebo controlled trials (RCT) are very important for testing efficacy and safety of a medical treatment. There is no too much RCT`s in childhood bipolar disorder manic episode.
Remzi Oğulcan Çıray, Pelin Hançer, Mustafa Tunçtürk, Neslihan İnal Emiroğlu   +3 more
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