Results 21 to 30 of about 364,712 (294)

Vertebroplasty and the Placebo Response [PDF]

Radiology, 2011
Our interpretation of the evidence for vertebroplasty has distinctive implications for clinical practice and health policy.
Franklin G, Miller, David F, Kallmes, Rachelle, Buchbinder   +2 more
openaire   +2 more sources

Placebo effect of an inert gel on experimentally induced leg muscle pain. [PDF]

, 2010
Purpose: This study examined the therapeutic effects of an inert placebo gel on experimentally induced muscle pain in a sports therapy setting. It aimed to investigate the degree to which conditioned analgesia, coupled with an expectation of intervention,
Coleman, Damian A, Beedie, C., Leach, G., Foad, A., Hopker, James G.   +4 more
core   +1 more source

Placebo-controlled pharmacological trials in child and adolescents with bipolar disorder manic episode (BPD-ME): Systematic review, meta-analysis and a meta-regression on placebo response (eng)

Klinik Psikiyatri Dergisi, 2020
Objective: Randomized placebo controlled trials (RCT) are very important for testing efficacy and safety of a medical treatment. There is no too much RCT`s in childhood bipolar disorder manic episode.
Remzi Oğulcan Çıray, Pelin Hançer, Mustafa Tunçtürk, Neslihan İnal Emiroğlu   +3 more
doaj   +1 more source

Objective response rate of placebo in randomized controlled trials of anticancer medicinesResearch in context

EClinicalMedicine, 2023
Summary: Background: Spontaneous regression of advanced solid tumors is infrequent but may occur. Quantifying response rates from placebo in cancer drug trials may provide important information for physicians, patients, and regulators.
Arushi Sachdev, Isobel Sharpe, Meghan Bowman, Christopher M. Booth, Bishal Gyawali   +4 more
doaj   +1 more source

Informed consent and placebo effects: a content analysis of information leaflets to identify what clinical trial participants are told about placebos [PDF]

, 2012
BackgroundPlacebo groups are used in randomised clinical trials (RCTs) to control for placebo effects, which can be large. Participants in trials can misunderstand written information particularly regarding technical aspects of trial design such as ...
Alison E. M. Adams (317941), George T. Lewith (317942), Kaptchuk, Ted J., Ted J Kaptchuk, Ted J. Kaptchuk (234474), Bishop Felicity L., Lewith George T., Adams, Alison E. M., Kaptchuk, Ted, Bishop, Felicity L., Felicity L. Bishop (317940), Adams Alison E. M., Alison E M Adams, Kaptchuk Ted J., Lewith, George, Lewith, George T., Felicity L Bishop, Adams, Alison E.M., George T Lewith   +18 more
core   +1 more source

Placebo Effects in Psychotherapy: A Framework

Frontiers in Psychiatry, 2019
The issue of placebo response and the extent of its effect on psychotherapy is complex for two specific reasons: i) Current standards for drug trials, e.g., true placebo interventions, double-blinding, cannot be applied to most psychotherapy techniques ...
Paul Enck, Stephan Zipfel
doaj   +1 more source

Comparison of indirect treatment methods in migraine prevention to address differences in mode of administration

Journal of Comparative Effectiveness Research, 2023
Aim: Indirect treatment comparisons (ITCs) are anchored on a placebo comparator, and the placebo response may vary according to drug administration route.
Howard Thom, Stephane A Regnier, Xin Ying Lee, Steven Kymes, Lene Vase   +4 more
doaj   +1 more source

Influence on study outcomes of an inpatient study by the behavior of the study staff (PINgPOng): study protocol for a randomized clinical trial

Trials, 2022
Background The placebo effect as the symptom improvement following inert treatments is a fixed component of RCTs to differentiate between specific effects of the tested pharmacological substance from other unspecific effects.
Martin Coenen, Ulrike Bingel, Matthias Zunhammer, Maria Soledad Berdaguer, Christine Fuhrmann, Rolf Fimmers, Jens Rengelshausen, Gunther Hartmann, Manfred Schedlowski, Christoph Coch   +9 more
doaj   +1 more source

Antidepressants versus placebo for depression in primary care [PDF]

, 2009
Background Concern has been expressed about the relevance of secondary care studies to primary care patients specifically about the effectiveness of antidepressant medication.
Grant Blashki, Tim Kenealy, Blashki, Grant, Stephen MacGillivray, Kerse, Ngaire, Ngaire Kerse, Felicity A Goodyear-Smith, Fishman, Tana, Goodyear-Smith, Felicity A., MacGillivray, Stephen; id_orcid, Elley, C. Raina, C Raina Elley, Arroll, Bruce, Bruce Arroll, Tana Fishman, Kenealy, Tim   +15 more
core   +1 more source

Placebo response and effect in randomized clinical trials: meta-research with focus on contextual effects

Trials, 2021
Background Contextual effects (i.e., placebo response) refer to all health changes resulting from administering an apparently inactive treatment. In a randomized clinical trial (RCT), the overall treatment effect (i.e., the post-treatment effect in the ...
Sigurlaug H. Hafliðadóttir, Carsten B. Juhl, Sabrina M. Nielsen, Marius Henriksen, Ian A. Harris, Henning Bliddal, Robin Christensen   +6 more
doaj   +1 more source