Results 21 to 30 of about 322,437 (184)
EClinicalMedicine, 2023 Summary: Background: Spontaneous regression of advanced solid tumors is infrequent but may occur. Quantifying response rates from placebo in cancer drug trials may provide important information for physicians, patients, and regulators.
Arushi Sachdev +4 more
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Placebo Effects in Psychotherapy: A Framework
Frontiers in Psychiatry, 2019 The issue of placebo response and the extent of its effect on psychotherapy is complex for two specific reasons: i) Current standards for drug trials, e.g., true placebo interventions, double-blinding, cannot be applied to most psychotherapy techniques ...
Paul Enck, Stephan Zipfel
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Trials, 2022 Background The placebo effect as the symptom improvement following inert treatments is a fixed component of RCTs to differentiate between specific effects of the tested pharmacological substance from other unspecific effects.
Martin Coenen +9 more
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Pharmacogenomics and the Placebo Response [PDF]
ACS Chemical Neuroscience, 2018 There is perhaps no more important time in the history of placebos to consider their role in clinical trials and in medicine. Increasingly well-designed pharmaceutical and academic clinical trials testing promising and established drug and surgical interventions have failed to "beat" the placebo response.
Kathryn T, Hall +2 more
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Journal of Comparative Effectiveness Research, 2023 Aim: Indirect treatment comparisons (ITCs) are anchored on a placebo comparator, and the placebo response may vary according to drug administration route.
Howard Thom +4 more
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Placebo Economics: A Systematic Review About the Economic Potential of Utilizing the Placebo Effect
Frontiers in Psychiatry, 2019 Background: Recent research shows that placebo mechanisms can be utilized in ethical and legal ways such as in open-label conditions, when patients know that they receive placebos, and through psychological interventions aiming to optimize patients ...
Jens Hamberger +6 more
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Placebo response in migraine [PDF]
European Journal of Clinical Pharmacology, 2010 Sir I am currently in the process of revising the Guidelines for Drug Trials in Migraine of The International Headache Society. While browsing the literature for information on the placebo response in migraine randomised clinical trials (RCTs), I read with interest the extensive meta-analysis on this subject published by Macedo et al.
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Placebo response in depression
Dialogues in Clinical Neuroscience, 2002 With its naturally fluctuating course, depression is a highly placebo-responsive condition: mean placebo response rates in antidepressant clinical trials are 30% to 40%. We review the history and terminology of placebo and the proposed mechanisms underlying the placebo response, including the physician-patient relationship and biological, sociocultural,
Shamsah B, Sonawalla +1 more
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Twenty years after ‘Listening to Prozac but hearing placebo’. Do we hear placebo even louder?
Health Psychology Report, 2019 An active placebo is a substance that produces side effects similar to an active ingredient while not producing the same intended therapeutic effect. The aim of this study is to review the literature on the hypothesis of the active placebo response as a ...
Wojciech Oronowicz-Jaśkowiak +1 more
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Placebo and the law of identification
Frontiers in PsychiatryThousands of essays and studies have been published on placebo and nocebo. Yet, despite this plethora of information, we are not much closer to a comprehensive understanding of the fundamental mechanism producing placebo and nocebo effects than we were ...
Steve F. Bierman +2 more
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