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Cutoff criteria for the placebo response: a cluster and machine learning analysis of placebo analgesia [PDF]
Scientific Reports, 2021 Computations of placebo effects are essential in randomized controlled trials (RCTs) for separating the specific effects of treatments from unspecific effects associated with the therapeutic intervention. Thus, the identification of placebo responders is
Per M. Aslaksen
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Report of similar placebo response in one internet versus onsite randomised controlled trials from the literature [PDF]
Osteoarthritis and Cartilage OpenObjective: The aim of this study was to compare the magnitude and the predictors of the placebo response in an internet versus onsite randomised controlled trials (RCTs) in people with hand osteoarthritis (HOA).
Arthur Ooghe +8 more
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Letter to Editor-response: placebo response rates [PDF]
EClinicalMedicine, 2023 Bishal Gyawali
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Journal of Pain Research, 2015 Roy Freeman,1 Birol Emir,2 Bruce Parsons2 1Autonomic and Peripheral Nerve Laboratory, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA; 2Pfizer Inc, New York, NY, USABackground: Greater understanding of factors associated ...
Freeman R, Emir B, Parsons B
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Frontiers in Psychology, 2023 IntroductionPlacebo responsiveness is highly variable across individuals. In the domain of pain, it may range from pronounced hypoalgesia to no response at all.
Helena Hartmann +5 more
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European Headache Federation recommendations for placebo and nocebo terminology
The Journal of Headache and Pain, 2020 Background and aim Despite recent publications, practitioners remain unfamiliar with the current terminology related to the placebo and nocebo phenomena observed in clinical trials and practice, nor with the factors that modulate them.
Dimos D. Mitsikostas +17 more
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Placebo Effects on Stress, but Not on Pain Reports. A Multi-Experiment Study
Frontiers in Psychology, 2021 BackgroundContextual factors, such as participant/experimenter sex may moderate the placebo effects. We tested whether the participant and experimenter sex modulated placebo effects on experimentally induced pain and associated stress.ObjectiveTo ...
Sara Magelssen Vambheim +2 more
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Placebo response in trichotillomania [PDF]
International Clinical Psychopharmacology, 2017 Background: Trichotillomania is a functionally impairing, often overlooked disorder with no FDA-approved medications indicated for its treatment. The ability of clinical trials to detect beneficial effects of pharmacologic treatment in trichotillomania has been hampered by the high placebo response rate.
Samuel R. Chamberlain +9 more
openaire +4 more sources
JAMA Network Open, 2020 Key Points Question Are subjective patient-reported outcomes vs objective biomarkers associated with higher placebo responses in clinical trials? Findings In this cross-sectional study examining the placebo arms of 5 randomized clinical trials of ...
J. Vollert +5 more
semanticscholar +1 more source
On the Relationship Between Pain Variability and Relief in Randomized Clinical Trials
Frontiers in Pain Research, 2022 Previous research reports suggest greater baseline variability is associated with greater pain relief in those who receive a placebo. However, studies that evidence this association do not control for confounding effects from regression to the mean and ...
Siddharth R. Tiwari +5 more
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