Results 31 to 40 of about 8,509,826 (346)
Trials, 2022 Background The placebo effect as the symptom improvement following inert treatments is a fixed component of RCTs to differentiate between specific effects of the tested pharmacological substance from other unspecific effects.
Martin Coenen +9 more
doaj +1 more source
Frontal alpha asymmetry: A potential biomarker of approach-withdrawal motivation towards pain
Frontiers in Pain Research, 2022 Pain-related catastrophising is a maladaptive coping strategy known to have a strong influence on clinical pain outcomes and treatment efficacy. Notwithstanding, little is known about its neurophysiological correlates.
Bárbara Silva-Passadouro +8 more
doaj +1 more source
Vertebroplasty and the Placebo Response [PDF]
Radiology, 2011 Our interpretation of the evidence for vertebroplasty has distinctive implications for clinical practice and health policy.
David F. Kallmes +2 more
openaire +3 more sources
Placebo Effects in Psychotherapy: A Framework
Frontiers in Psychiatry, 2019 The issue of placebo response and the extent of its effect on psychotherapy is complex for two specific reasons: i) Current standards for drug trials, e.g., true placebo interventions, double-blinding, cannot be applied to most psychotherapy techniques ...
Paul Enck, Stephan Zipfel
doaj +1 more source
Placebo Economics: A Systematic Review About the Economic Potential of Utilizing the Placebo Effect
Frontiers in Psychiatry, 2019 Background: Recent research shows that placebo mechanisms can be utilized in ethical and legal ways such as in open-label conditions, when patients know that they receive placebos, and through psychological interventions aiming to optimize patients ...
Jens Hamberger +6 more
doaj +1 more source
Journal of Comparative Effectiveness Research, 2023 Aim: Indirect treatment comparisons (ITCs) are anchored on a placebo comparator, and the placebo response may vary according to drug administration route.
Howard Thom +4 more
doaj +1 more source
Assessing surrogate endpoints in vaccine trials with case-cohort sampling and the Cox model [PDF]
Annals of Applied Statistics 2008, Vol. 2, No. 1, 386-407, 2008 Assessing immune responses to study vaccines as surrogates of protection plays a central role in vaccine clinical trials. Motivated by three ongoing or pending HIV vaccine efficacy trials, we consider such surrogate endpoint assessment in a randomized placebo-controlled trial with case-cohort sampling of immune responses and a time to event endpoint ...
arxiv +1 more source
Schizophrenia bulletin, 2019 We conducted a meta-regression analysis of all double-blind, randomized, placebo-controlled clinical trials (DBRCTs) reporting effects of drug and placebo on negative symptoms in people with stable schizophrenia and predominant or prominent negative ...
D. Fraguas +4 more
semanticscholar +1 more source
Annals of the Rheumatic Diseases, 2021 Objective To evaluate the efficacy and safety of the Janus kinase-1-preferential inhibitor filgotinib versus placebo or tumour necrosis factor-α inhibitor therapy in patients with active rheumatoid arthritis (RA) despite ongoing treatment with ...
B. Combe +19 more
semanticscholar +1 more source
Placebo response in migraine [PDF]
European Journal of Clinical Pharmacology, 2010 Sir I am currently in the process of revising the Guidelines for Drug Trials in Migraine of The International Headache Society. While browsing the literature for information on the placebo response in migraine randomised clinical trials (RCTs), I read with interest the extensive meta-analysis on this subject published by Macedo et al.
openaire +3 more sources