Results 91 to 100 of about 10,967 (189)

Embryonic attenuated Wnt/β-catenin signaling defines niche location and long-term stem cell fate in hair follicle

open access: yeseLife, 2015
Long-term adult stem cells sustain tissue regeneration throughout the lifetime of an organism. They were hypothesized to originate from embryonic progenitor cells that acquire long-term self-renewal ability and multipotency at the end of organogenesis ...
Zijian Xu   +7 more
doaj   +1 more source

The Development of the Human Female Reproductive Tract. Part 1: Uterine Tube and Uterus

open access: yesClinical Anatomy, Volume 39, Issue 1, Page 92-111, January 2026.
ABSTRACT The uterine tubes and uterus develop from the paramesonephric (Müllerian) ducts. Most experimental data are obtained in rodents. Since the (micro‐)anatomy of the murine urogenital tract differs from that in humans, evaluation of the translatability of mouse data to human development is relevant.
Cindy J. M. Hülsman   +4 more
wiley   +1 more source

Developing an ancient epithelial appendage: FGF signalling regulates early tail denticle formation in sharks

open access: yesEvoDevo, 2017
Background Vertebrate epithelial appendages constitute a diverse group of organs that includes integumentary structures such as reptilian scales, avian feathers and mammalian hair.
Rory L. Cooper   +3 more
doaj   +1 more source

The cellular basis of mechanosensory Merkel-cell innervation during development

open access: yeseLife, 2019
Touch sensation is initiated by mechanosensory neurons that innervate distinct skin structures; however, little is known about how these neurons are patterned during mammalian skin development.
Blair A Jenkins   +4 more
doaj   +1 more source

Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control

open access: yes
The Journal of Physiology, EarlyView.
Richard J. A. Wilson   +1 more
wiley   +1 more source

Two-step regulation of trachealess ensures tight coupling of cell fate with morphogenesis in the Drosophila trachea

open access: yeseLife, 2019
During organogenesis, inductive signals cause cell differentiation and morphogenesis. However, how these phenomena are coordinated to form functional organs is poorly understood.
Takefumi Kondo, Shigeo Hayashi
doaj   +1 more source

c-Myb knockdown increases the neomycin-induced damage to hair-cell-like HEI-OC1 cells in vitro

open access: yesScientific Reports, 2017
c-Myb is a transcription factor that plays a key role in cell proliferation, differentiation, and apoptosis. It has been reported that c-Myb is expressed within the chicken otic placode, but whether c-Myb exists in the mammalian cochlea, and how it ...
Xiaoyu Yu   +13 more
semanticscholar   +1 more source

Localized Electroporation: A Method for Targeting Expression of Genes in Avian Embryos

open access: yesBioTechniques, 2000
Avian embryos are a popular model for cell and developmental biologists. However, analysis of gene function in living embryos has been hampered by difficulties in targeting the expression of exogenous genes.
Ross L. Atkins   +2 more
doaj   +1 more source

The Amphioxus SoxB Family: Implications for the Evolution of Vertebrate Placodes

open access: yesInternational Journal of Biological Sciences, 2007
Cranial placodes are regions of thickened ectoderm that give rise to sense organs and ganglia in the vertebrate head. Homologous structures are proposed to exist in urochordates, but have not been found in cephalochordates, suggesting the first chordates
Daniel Meulemans, Marianne Bronner-Fraser
doaj  

Frequent and biased odorant receptor (OR) re-selection in an olfactory placode-derived cell line

open access: yesPLOS ONE, 2018
We previously characterized a clonal olfactory placode-derived cell line (OP6) as a model system for studying odorant receptor (OR) choice, where individual OP6 cells, similar to olfactory sensory neurons in vivo, transcribe one allele ("monoallelic") of one OR gene ("monogenic"). The OP6 cell line provides a unique opportunity to investigate intrinsic
J. C. Noble   +2 more
openaire   +4 more sources

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