Results 21 to 30 of about 10,967 (189)

EARLY STEPS IN INNER EAR DEVELOPMENT: INDUCTION AND MORPHOGENESIS OF THE OTIC PLACODE

Frontiers in Pharmacology, 2015
Various cellular replacement therapies using in vitro generated cells to replace damaged tissue have been proposed as strategies to alleviate hearing loss.
Xaiorei eSai, Raj K. Ladher
doaj   +2 more sources

Derivation of Diverse Hormone-Releasing Pituitary Cells from Human Pluripotent Stem Cells

Stem Cell Reports, 2016
Summary: Human pluripotent stem cells (hPSCs) provide an unlimited cell source for regenerative medicine. Hormone-producing cells are particularly suitable for cell therapy, and hypopituitarism, a defect in pituitary gland function, represents a ...
Bastian Zimmer, Jinghua Piao, Kiran Ramnarine, Mark J. Tomishima, Viviane Tabar, Lorenz Studer   +5 more
doaj   +2 more sources

Neural crest cell-placodal neuron interactions are mediated by Cadherin-7 and N-cadherin during early chick trigeminal ganglion assembly [version 2; peer review: 1 approved, 2 approved with reservations]

F1000Research, 2022
Background: Arising at distinct positions in the head, the cranial ganglia are crucial for integrating various sensory inputs. The largest of these ganglia is the trigeminal ganglion, which relays pain, touch and temperature information through its three
Chyong-Yi Wu, Lisa A. Taneyhill, Caroline A. Halmi   +2 more
doaj   +1 more source

Retroviral lineage analysis reveals dual contribution from ectodermal placodes and neural crest cells to avian olfactory sensory and GnRH neurons

Natural Sciences, 2022
The origin of the neurons and glia in the olfactory system of vertebrates has been controversial, with different cell types attributed to being of ectodermal placode versus neural crest lineage, depending upon the species.
Alison Koontz, Hugo A. Urrutia, Marianne E. Bronner   +2 more
doaj   +1 more source

Selective disruption of trigeminal sensory neurogenesis and differentiation in a mouse model of 22q11.2 deletion syndrome

Disease Models & Mechanisms, 2022
22q11.2 Deletion Syndrome (22q11DS) is a neurodevelopmental disorder associated with cranial nerve anomalies and disordered oropharyngeal function, including pediatric dysphagia. Using the LgDel 22q11DS mouse model, we investigated whether sensory neuron
Beverly A. Karpinski, Thomas M. Maynard, Corey A. Bryan, Gelila Yitsege, Anelia Horvath, Norman H. Lee, Sally A. Moody, Anthony-Samuel LaMantia   +7 more
doaj   +1 more source

Neural crest cell-placodal neuron interactions are mediated by Cadherin-7 and N-cadherin during early chick trigeminal ganglion assembly [version 1; peer review: 1 approved, 2 approved with reservations]

F1000Research, 2022
Background: Arising at distinct positions in the head, the cranial ganglia are crucial for integrating various sensory inputs. The largest of these ganglia is the trigeminal ganglion, which relays pain, touch and temperature information through its three
Chyong-Yi Wu, Lisa A. Taneyhill, Caroline A. Halmi   +2 more
doaj   +1 more source

Neurogenin 2 and Neuronal Differentiation 1 Control Proper Development of the Chick Trigeminal Ganglion and Its Nerve Branches

Journal of Developmental Biology, 2023
The trigeminal ganglion contains the cell bodies of sensory neurons comprising cranial nerve V, which relays information related to pain, touch, and temperature from the face and head to the brain.
Parinaz Bina, Margaret A. Hines, Johena Sanyal, Lisa A. Taneyhill   +3 more
doaj   +1 more source

Fgf3 and Fgf10a work in concert to promote maturation of the epibranchial placodes in zebrafish. [PDF]

PLoS ONE, 2013
Essential cellular components of the paired sensory organs of the vertebrate head are derived from transient thickenings of embryonic ectoderm known as cranial placodes.
Matthew N McCarroll, Alex V Nechiporuk
doaj   +1 more source

Loss of Elp1 disrupts trigeminal ganglion neurodevelopment in a model of familial dysautonomia

eLife, 2022
Familial dysautonomia (FD) is a sensory and autonomic neuropathy caused by mutations in elongator complex protein 1 (ELP1). FD patients have small trigeminal nerves and impaired facial pain and temperature perception.
Carrie E Leonard, Jolie Quiros, Frances Lefcort, Lisa A Taneyhill   +3 more
doaj   +1 more source

Ectodysplasin A1 promotes placodal cell fate during early morphogenesis of ectodermal appendages [PDF]

Development, 2004
Organs developing as appendages of the ectoderm are initiated from epithelial thickenings called placodes. Their formation is regulated by interactions between the ectoderm and underlying mesenchyme, and several signalling molecules have been implicated as activators or inhibitors of placode formation.
Mustonen, T., Ilmonen, M., Pummila, M., Kangas, A.T., Laurikkala, J., Jaatinen, R., Pispa, J., Gaide, O., Schneider, P., Thesleff, I., Mikkola, M.L.   +10 more
openaire   +3 more sources