Results 41 to 50 of about 10,967 (189)
Frontiers in Physiology, 2020 Development of the vertebrate head is a complex and dynamic process, which requires integration of all three germ layers and their derivatives. Of special importance are ectoderm-derived cells that form the cranial placodes, which then differentiate into
Soma Dash +9 more
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Graded levels of Pax2a and Pax8 regulate cell differentiation during sensory placode formation [PDF]
Development, 2012 Pax gene haploinsufficiency causes a variety of congenital defects. Renal-coloboma syndrome, resulting from mutations in Pax2, is characterized by kidney hypoplasia, optic nerve malformation, and hearing loss. Although this underscores the importance of Pax gene dosage in normal development, how differential levels of these transcriptional regulators ...
Matthew N, McCarroll +5 more
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Frontiers in Physiology, 2020 The mouse tongue possesses three types of gustatory papillae: large circumvallate papillae (CVP), foliate papillae (FOP) and fungiform papillae (FFP). Although CVP is the largest papilla and contain a high density of taste buds, little is known about CVP
Sushan Zhang +3 more
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Lens apoptosis in the Astyanax blind cavefish is not triggered by its small size or defects in morphogenesis. [PDF]
PLoS ONE, 2017 Blindness is a convergent trait in many cave animals of various phyla. Astyanax mexicanus cavefish is one of the best studied cave animals; however the mechanisms underlying eye degeneration in this species are not yet completely understood.
Hélène Hinaux +5 more
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Developmental Cell, 2019 Cell fate transitions are essential for specification of stem cells and their niches, but the precise timing and sequence of molecular events during embryonic development are largely unknown.
Ka‐Wai Mok +14 more
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eLife, 2017 Neural patterning involves regionalised cell specification. Recent studies indicate that cell dynamics play instrumental roles in neural pattern refinement and progression, but the impact of cell behaviour and morphogenesis on neural specification is not
Esteban Hoijman +3 more
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Differentiation of Cell Types from Non-Neurogenic Placodes
, 2021 Chapter 8 reviews how cell types derived from the non-neurogenic placodea, i.e. the lens and adenohypophyseal placodes, differentiate. The lens placode gives rise to lens fiber cells, which are rendered transparent by the accumulation of crystallin proteins.
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Notch signalling regulates epibranchial placode patterning and segregation
Development, 2020 Epibranchial placodes are the geniculate, petrosal and nodose placodes that generate parts of cranial nerves VII, IX and X, respectively. How the three spatially separated placodes are derived from the common posterior placodal area is poorly understood.
Li Wang +7 more
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Cell fate specification in the lingual epithelium is controlled by antagonistic activities of Sonic hedgehog and retinoic acid. [PDF]
PLoS Genetics, 2017 The interaction between signaling pathways is a central question in the study of organogenesis. Using the developing murine tongue as a model, we uncovered unknown relationships between Sonic hedgehog (SHH) and retinoic acid (RA) signaling.
Maha El Shahawy +8 more
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Cadherin-7 mediates proper neural crest cell-placodal neuron interactions during trigeminal ganglia assembly [PDF]
genesis, 2018 ABSTRACTThe cranial trigeminal ganglia play a vital role in the peripheral nervous system through their relay of sensory information from the vertebrate head to the brain. These ganglia are generated from the intermixing and coalescence of two distinct cell populations: cranial neural crest cells and placodal neurons.
Chyong‐Yi Wu, Lisa A. Taneyhill
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