Cell autonomous polarization by the planar cell polarity signaling pathway [PDF]
Nature Communications, 2023 As epithelial cells polarize in the tissue plane, the Planar Cell Polarity (PCP) signaling module segregates two distinct molecular subcomplexes to opposite sides of cells.
Alexis T. Weiner +5 more
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eLife, 2017 Both oriented cell divisions and cell rearrangements are critical for proper embryogenesis and organogenesis. However, little is known about how these two cellular events are integrated.
Yuwei Li +3 more
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Planar cell polarity in organ formation. [PDF]
Current Opinion in Cell Biology, 2018 The planar cell polarity (PCP) pathway controls a variety of morphological events across many species. During embryonic development, the PCP pathway regulates coordinated behaviour of groups of cells to direct morphogenetic processes such as convergent ...
D. Henderson, D. Long, C. Dean
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Wnt-frizzled planar cell polarity signaling in the regulation of cell motility. [PDF]
Curr Top Dev Biol, 2022 Koca Y, Collu GM, Mlodzik M.
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Coupling Planar Cell Polarity Signaling to Morphogenesis [PDF]
The Scientific World Journal, 2002 Epithelial cells and other groups of cells acquire a polarity orthogonal to their apical–basal axes, referred to as Planar Cell Polarity (PCP). The process by which these cells become polarized requires a signaling pathway using Frizzled as a receptor ...
Jeffrey D. Axelrod, Helen McNeill
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PCP auto count: a novel Fiji/ImageJ plug-in for automated quantification of planar cell polarity and cell counting [PDF]
Frontiers in Cell and Developmental BiologyIntrodution: During development, planes of cells give rise to complex tissues and organs. The proper functioning of these tissues is critically dependent on proper inter- and intra-cellular spatial orientation, a feature known as planar cell polarity ...
Kendra L. Stansak +5 more
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Wnt/planar cell polarity signaling controls morphogenetic movements of gastrulation and neural tube closure. [PDF]
Cell Mol Life Sci, 2022 Shi DL.
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Planar cell polarity in development and disease
Nature Reviews Molecular Cell Biology, 2017 Mitchell T. Butler, John B. Wallingford
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How do the Fat–Dachsous and core planar polarity pathways act together and independently to coordinate polarized cell behaviours? [PDF]
Open Biology, 2021 Planar polarity describes the coordinated polarization of cells within the plane of a tissue. This is controlled by two main pathways in Drosophila: the Frizzled-dependent core planar polarity pathway and the Fat–Dachsous pathway.
Helen Strutt, David Strutt
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Conserved and Divergent Principles of Planar Polarity Revealed by Hair Cell Development and Function
Frontiers in Neuroscience, 2021 Planar polarity describes the organization and orientation of polarized cells or cellular structures within the plane of an epithelium. The sensory receptor hair cells of the vertebrate inner ear have been recognized as a preeminent vertebrate model ...
Michael R. Deans, Michael R. Deans
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