A role for Myo-II zipper and spaghetti squash in Gliotactin-dependent Drosophila melanogaster wing hair planar cell polarity. [PDF]
PLoS ONEPlanar cell polarity, polarization in the plane of an epithelium, is critical for tissue development. The Drosophila melanogaster wing epithelium is an important model system for planar cell polarity establishment and has greatly informed studies in ...
Chase Holland +13 more
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A New Spin on Planar Cell Polarity [PDF]
Cell, 2010 The generation of planar cell polarity (PCP) and tissue shape during morphogenesis is tightly linked, but it is not clear how. Aigouy et al. (2010) now show in the developing Drosophila wing that PCP initially has a radial orientation that becomes ...
Patricio Olguin +3 more
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Planar Cell Polarity Signaling: Coordinated Crosstalk for Cell Orientation [PDF]
Journal of Developmental BiologyThe planar cell polarity (PCP) system is essential for positioning cells in 3D networks to establish the proper morphogenesis, structure, and function of organs during embryonic development.
Sandeep Kacker +7 more
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The planar cell polarity pathway in vertebrate development
Developmental Dynamics, 2011 Directing the orientation of cells in three dimensions is a fundamental aspect of many of the processes underlying the generation of the appropriate shape and function of tissues and organs during embryonic development.
Meijlink, F., Wansleeben, C.
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Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division [PDF]
eLife, 2017 Polarity is a shared feature of most cells. In epithelia, apical-basal polarity often coexists, and sometimes intersects with planar cell polarity (PCP), which orients cells in the epithelial plane. From a limited set of core building blocks (e.g.
Jennifer J Banerjee +5 more
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Coupling Planar Cell Polarity Signaling to Morphogenesis
The Scientific World Journal, 2002 Epithelial cells and other groups of cells acquire a polarity orthogonal to their apical–basal axes, referred to as Planar Cell Polarity (PCP). The process by which these cells become polarized requires a signaling pathway using Frizzled as a receptor ...
Jeffrey D. Axelrod, Helen McNeill
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PCP auto count: a novel Fiji/ImageJ plug-in for automated quantification of planar cell polarity and cell counting [PDF]
Frontiers in Cell and Developmental BiologyIntrodution: During development, planes of cells give rise to complex tissues and organs. The proper functioning of these tissues is critically dependent on proper inter- and intra-cellular spatial orientation, a feature known as planar cell polarity ...
Kendra L. Stansak +5 more
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A systems biology approach to multi-scale modelling and analysis of planar cell polarity in drosophila melanogaster wing [PDF]
, 2013 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Systems biology aims to describe and understand biology at a global scale where biological systems function as a result of complex mechanisms that happen at
Gao, Qian
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The Biological Significance and Implications of Planar Cell Polarity for Nephrology
Frontiers in Physiology, 2021 The orientation of cells in two-dimensional and three-dimensional space underpins how the kidney develops and responds to disease. The process by which cells orientate themselves within the plane of a tissue is termed planar cell polarity. In this Review,
Eugenia Papakrivopoulou +5 more
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Conserved and Divergent Principles of Planar Polarity Revealed by Hair Cell Development and Function
Frontiers in Neuroscience, 2021 Planar polarity describes the organization and orientation of polarized cells or cellular structures within the plane of an epithelium. The sensory receptor hair cells of the vertebrate inner ear have been recognized as a preeminent vertebrate model ...
Michael R. Deans, Michael R. Deans
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