Results 21 to 30 of about 150,481 (338)
Biomechanical regulation of planar cell polarity in endothelial cells.
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2022 Cell polarity refers to the uneven distribution of certain cytoplasmic components in a cell with a spatial order. The planar cell polarity (PCP), the cell aligns perpendicular to the polar plane, in endothelial cells (ECs) has become a research hot spot.
Caihong Wang +6 more
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Nature Communications, 2021 The phenomenon of tissue fluidity—cells’ ability to rearrange relative to each other in confluent tissues—has been linked to several morphogenetic processes and diseases, yet few molecular regulators of tissue fluidity are known. Ommatidial rotation (OR),
Nabila Founounou +5 more
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Frontiers in Cell and Developmental Biology, 2022 Planar cell polarity (PCP) signaling polarizes cells within the plane of an epithelium. In the airways, planar cell polarity signaling orients the directional beating of motile cilia required for effective mucociliary clearance.
Koshi Kunimoto +4 more
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Science Advances, 2021 Amyloid beta oligomers cause glutamatergic synapse degeneration by targeting the planar cell polarity components in the synapses. The signaling pathway directly controlling the maintenance of adult glutamatergic synapses has not been well understood ...
Bo Feng +7 more
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Planar cell polarity in Drosophila [PDF]
Organogenesis, 2011 In all multicellular organisms, epithelial cells are not only polarized along the apical-basal axis, but also within the epithelial plane, giving cells a sense of direction. Planar cell polarity (PCP) signaling regulates establishment of polarity within the plane of an epithelium.
Saw Myat Thanda W, Maung, Andreas, Jenny
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Science Advances, 2021 The glutamatergic synapses are assembled and maintained by conserved planar cell polarity proteins.
Y. Ban +6 more
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Morphogenetic forces planar polarize LGN/Pins in the embryonic head during Drosophila gastrulation
eLife, 2022 Spindle orientation is often achieved by a complex of Partner of Inscuteable (Pins)/LGN, Mushroom Body Defect (Mud)/Nuclear Mitotic Apparatus (NuMa), Gαi, and Dynein, which interacts with astral microtubules to rotate the spindle.
Jaclyn Camuglia +2 more
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Cell packing influences planar cell polarity signaling [PDF]
Proceedings of the National Academy of Sciences, 2008 Some epithelial cells display asymmetry along an axis orthogonal to the apical-basal axis, referred to as planar cell polarity (PCP). A Frizzled-mediated feedback loop coordinates PCP between neighboring cells, and the cadherin Fat transduces a global directional cue that orients PCP with respect to the tissue axes.
Dali, Ma +5 more
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Cell Reports, 2018 Summary: Planar polarity, the coordinated polarization of cells in the plane of a tissue, is important for normal tissue development and function. Proteins of the core planar polarity pathway become asymmetrically localized at the junctions between cells
Margarida Ressurreição +2 more
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Fly, 2011 Scientists like to consider themselves as especially objective, but, however hard we try we cannot be very different from everyone else. Like them we helplessly absorb our knowledge, our perspectives, our valuation of whether something is exciting or boring from those around us.
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