A screen for round egg mutants in Drosophila identifies tricornered, furry, and misshapen as regulators of egg chamber elongation. [PDF]
, 2012 The elongation of tissues and organs during embryonic development results from the coordinate polarization of cell behaviors with respect to the elongation axis.
Bilder, David +4 more
core +2 more sources
Pericytes promote skin regeneration by inducing epidermal cell polarity and planar cell divisions
Life Science Alliance, 2018 This study reveals that mesenchymal stem cell–like dermal pericytes increase the number of epidermal stem and progenitor cells in human skin by promoting planar cell divisions within the proliferative compartment, without compromising skin ...
Lizhe Zhuang +5 more
semanticscholar +1 more source
Planar cell polarity induces local microtubule bundling for coordinated ciliary beating
Journal of Cell Biology, 2021 Nakayama et al. show that Daple is responsible for the increased microtubule (MT) density on the Frizzled side of the apical junctional complex (AJC) in multiciliated cells via bundling and stabilizing MTs and mediating interactions between MTs and the ...
Shogo Nakayama +13 more
semanticscholar +1 more source
Biology Open, 2015 Hair cells of the organ of Corti (OC) of the cochlea exhibit distinct planar polarity, both at the tissue and cellular level. Planar polarity at tissue level is manifested as uniform orientation of the hair cell stereociliary bundles. Hair cell intrinsic
Anna Kirjavainen +3 more
doaj +1 more source
Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis extension during zebrafish gastrulation [PDF]
, 2017 Cell proliferation has generally been considered dispensable for anteroposterior extension of embryonic axis during vertebrate gastrulation. Signal transducer and activator of transcription 3 (Stat3), a conserved controller of cell proliferation ...
Liu, Yinzi +2 more
core +4 more sources
Cadherin-26 (CDH26) regulates airway epithelial cell cytoskeletal structure and polarity. [PDF]
, 2018 Polarization of the airway epithelial cells (AECs) in the airway lumen is critical to the proper function of the mucociliary escalator and maintenance of lung health, but the cellular requirements for polarization of AECs are poorly understood.
Fahy, John V +8 more
core +3 more sources
Frizzled-Dependent Planar Cell Polarity without Secreted Wnt Ligands
Developmental Cell, 2020 Summary Planar cell polarity (PCP) organizes the orientation of cellular protrusions and migratory activity within the tissue plane. PCP establishment involves the subcellular polarization of core PCP components.
Joyce J S Yu +6 more
semanticscholar +1 more source
Planar cell polarity and the kidney [PDF]
Nephrology Dialysis Transplantation, 2013 Planar cell polarity (PCP) is the uniform orientation and alignment of a group of cells orthogonal to the apical-basal axis within a tissue. Originally described in insects, it is now known that PCP is required for many processes in vertebrates, including directional cell movement, polarized cell division, ciliary orientation, neural tube closure ...
Papakrivopoulou, E +3 more
openaire +5 more sources
Arabidopsis SABRE and CLASP interact to stabilize cell division plane orientation and planar polarity [PDF]
, 2013 The orientation of cell division and the coordination of cell polarity within the plane of the tissue layer (planar polarity) contribute to shape diverse multicellular organisms. The root of Arabidopsis thaliana displays regularly oriented cell divisions,
Alonso, J.M. +8 more
core +1 more source
No Evidence that Wnt Ligands Are Required for Planar Cell Polarity in Drosophila
Cell Reports, 2020 SUMMARY The frizzled (fz) and dishevelled (dsh) genes are highly conserved members of both the planar cell polarity (PCP) pathway and the Wnt signaling pathway.
Ben Ewen-Campen +3 more
semanticscholar +1 more source