Results 31 to 40 of about 22,555 (293)
CPLANE Complex and Ciliopathies
Biomolecules, 2022 Primary cilia are non-motile organelles associated with the cell cycle, which can be found in most vertebrate cell types. Cilia formation occurs through a process called ciliogenesis, which involves several mechanisms including planar cell polarity (PCP)
Jesús Eduardo Martín-Salazar +1 more
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Frontiers in Cell and Developmental Biology, 2019 Formation of the anteroposterior and dorsoventral body axis in Caenorhabditis elegans depends on cortical flows and advection of polarity determinants. The role of this patterning mechanism in tissue polarization after formation of cell-cell contacts is ...
Priyanka Dutta +2 more
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Afferent neurons of the zebrafish lateral line are strict selectors of hair-cell orientation. [PDF]
PLoS ONE, 2009 Hair cells in the inner ear display a characteristic polarization of their apical stereocilia across the plane of the sensory epithelium. This planar orientation allows coherent transduction of mechanical stimuli because the axis of morphological ...
Adèle Faucherre +3 more
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Fly, 2011 Scientists like to consider themselves as especially objective, but, however hard we try we cannot be very different from everyone else. Like them we helplessly absorb our knowledge, our perspectives, our valuation of whether something is exciting or boring from those around us.
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Planar cell polarity in organ formation [PDF]
Current Opinion in Cell Biology, 2018 The planar cell polarity (PCP) pathway controls a variety of morphological events across many species. During embryonic development, the PCP pathway regulates coordinated behaviour of groups of cells to direct morphogenetic processes such as convergent extension and collective cell migration. In this review we discuss the increasingly prominent role of
Henderson, DJ, Long, DA, Dean, CH
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The cell biology of planar cell polarity [PDF]
Journal of Cell Biology, 2014 Planar cell polarity (PCP) refers to the coordinated alignment of cell polarity across the tissue plane. Key to the establishment of PCP is asymmetric partitioning of cortical PCP components and intercellular communication to coordinate polarity between neighboring cells.
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Planar Polarity: Forcing Cells Into Line [PDF]
Current Biology, 2015 Polarisation of tissues in the plane of an epithelium is fundamental for both animal morphogenesis and organ function. A new paper describes a role for mechanical cues in determining how such polarity is aligned with the body axes.
Strutt, Helen, Strutt, David
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Methods for studying planar cell polarity [PDF]
Methods, 2014 Planar cell polarity (PCP) is the polarity of epithelial cells in the plane orthogonal to the apical-basal axis, and is controlled by a partially defined signaling system. PCP related signaling also plays roles in cell migration, tissue re-organization and stem cell differentiation during embryonic development, and later, in regeneration and repair ...
Jessica, Olofsson, Jeffrey D, Axelrod
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G3: Genes, Genomes, Genetics, 2017 The Planar cell Polarity Effector (PPE) genes inturned, fuzzy, and fritz are downstream components in the frizzled/starry night signaling pathway, and their function is instructed by upstream Planar Cell Polarity (PCP) core genes such as frizzled and ...
Ying Wang +2 more
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Planar cell polarity signaling in vertebrates [PDF]
BioEssays, 2007 AbstractPlanar cell polarity (PCP) refers to the polarization of a field of cells within the plane of a cell sheet. This form of polarization is required for diverse cellular processes in vertebrates, including convergent extension (CE), the establishment of PCP in epithelial tissues and ciliogenesis. Perhaps the most distinct example of vertebrate PCP
Chonnettia, Jones, Ping, Chen
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