Results 41 to 50 of about 150,481 (338)

Planar cell polarity signaling in vertebrates [PDF]

BioEssays, 2007
AbstractPlanar cell polarity (PCP) refers to the polarization of a field of cells within the plane of a cell sheet. This form of polarization is required for diverse cellular processes in vertebrates, including convergent extension (CE), the establishment of PCP in epithelial tissues and ciliogenesis. Perhaps the most distinct example of vertebrate PCP
Chonnettia, Jones, Ping, Chen
openaire   +2 more sources

Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation [PDF]

, 2006
The planar cell polarity (PCP) pathway is conserved throughout evolution, but it mediates distinct developmental processes. In Drosophila, members of the PCP pathway localize in a polarized fashion to specify the cellular polarity within the plane of the
Brinkman, Brendan C., Chen, Ping, Dickinson, Mary E., Fraser, Scott E., Hamblet, Natasha S., Mark, Sharayne, Segil, Neil, Wallingford, John B., Wang, Jianbo, Wynshaw-Boris, Anthony   +9 more
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Nodal and planar cell polarity signaling cooperate to regulate zebrafish convergence and extension gastrulation movements

eLife, 2020
During vertebrate gastrulation, convergence and extension (C and E) of the primary anteroposterior (AP) embryonic axis is driven by polarized mediolateral (ML) cell intercalations and is influenced by AP axial patterning. Nodal signaling is essential for
Margot L. K. Williams, L. Solnica-Krezel
semanticscholar   +1 more source

Planar cell polarity of the kidney [PDF]

Experimental Cell Research, 2016
Planar cell polarity (PCP) or tissue polarity refers to the polarization of tissues perpendicular to the apical-basal axis. Most epithelia, including the vertebrate kidney, show signs of planar polarity. In the kidney, defects in planar polarity are attributed to several disease states including multiple forms of cystic kidney disease.
Ulrike, Schnell, Thomas J, Carroll
openaire   +2 more sources

CPLANE Complex and Ciliopathies

Biomolecules, 2022
Primary cilia are non-motile organelles associated with the cell cycle, which can be found in most vertebrate cell types. Cilia formation occurs through a process called ciliogenesis, which involves several mechanisms including planar cell polarity (PCP)
Jesús Eduardo Martín-Salazar, Diana Valverde   +1 more
doaj   +1 more source

Cell polarity and planar cell polarity (PCP) in spermatogenesis

Seminars in Cell & Developmental Biology, 2018
In adult mammalian testes, spermatids, most notably step 17-19 spermatids in stage IV-VIII tubules, are aligned with their heads pointing toward the basement membrane and their tails toward the tubule lumen. On the other hand, these polarized spermatids also align across the plane of seminiferous epithelium, mimicking planar cell polarity (PCP) found ...
Haiqi, Chen, Dolores D, Mruk, Wing-Yee, Lui, Chris K C, Wong, Will M, Lee, C Yan, Cheng   +5 more
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Planar Asymmetries in the C. elegans Embryo Emerge by Differential Retention of aPARs at Cell-Cell Contacts

Frontiers in Cell and Developmental Biology, 2019
Formation of the anteroposterior and dorsoventral body axis in Caenorhabditis elegans depends on cortical flows and advection of polarity determinants. The role of this patterning mechanism in tissue polarization after formation of cell-cell contacts is ...
Priyanka Dutta, Devang Odedra, Christian Pohl   +2 more
doaj   +1 more source

Afferent neurons of the zebrafish lateral line are strict selectors of hair-cell orientation. [PDF]

PLoS ONE, 2009
Hair cells in the inner ear display a characteristic polarization of their apical stereocilia across the plane of the sensory epithelium. This planar orientation allows coherent transduction of mechanical stimuli because the axis of morphological ...
Adèle Faucherre, Jesús Pujol-Martí, Koichi Kawakami, Hernán López-Schier   +3 more
doaj   +1 more source

PRICKLE1-related early onset epileptic encephalopathy [PDF]

, 2018
The PRICKLE1 (Prickle Planar Cell Polarity Protein 1-MIM 608500) gene is involved in different phases of human development. The related diseases include autosomal recessive progressive myoclonus epilepsy - ataxia syndrome, neural tube defects associated ...
DI NOIA, S, Leuzzi, V, Martinelli, M, Mastrangelo, M, Parrini, E, Tolve, M   +5 more
core   +1 more source

Noncanonical Wnt planar cell polarity signaling in lung development and disease.

Biochemical Society Transactions, 2020
The planar cell polarity (PCP) signaling pathway is a potent developmental regulator of directional cell behaviors such as migration, asymmetric division and morphological polarization that are critical for shaping the body axis and the complex three ...
Eszter K. Vladar, M. Königshoff
semanticscholar   +1 more source