Results 51 to 60 of about 66,520 (235)

Interaction of genetic risk score (GRS) and Plant-Based diet on atherogenic factors and body fat distribution indices among women with overweight and obesity: a cross-sectional study

Scientific Reports
The association between plant-based diets, obesity, cardiovascular disease (CVD), and genetic predisposition is still not fully understood. This study explored how plant-based diets interact with genetic susceptibility to atherosclerosis and body fat in ...
Mahya Mehri Hajmir, Atieh Mirzababaei, Faezeh Abaj, Yasaman Aali, Mahsa Samadi, Khadijeh Mirzaei   +5 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Association of changes in plant-based diet consumption with all-cause mortality among older adults in China: a prospective study from 2008 to 2019

The Journal of Nutrition, Health and Aging
Objectives: To examine the association of changes in plant-based diet consumption with all-cause mortality among older adults in China. Design: Cohort study. Setting: This cohort study of 11 years used data from the Chinese Longitudinal Healthy Longevity
Shen Huang, Yiling Lou, Shiqi Wang, Qiqi You, Qingqing Jiang, Shiyi Cao   +5 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Analyzing dietary exposure to critical nutrients on a plant-based diet using the food- and total nutrient index

Nutrition Journal
Abstract Background Unfortified plant-based diets are devoid of vitamin B12, and supply low intakes of iodine, zinc, selenium, and calcium. To disentangle the complex interplay between nutritional adequacy and nutrient intakes from supplements and foods in plant-based diets, data from a Germany-based cross-sectional ...
Maximilian Andreas Storz, Frieda Stübing, Luciana Hannibal, Roman Huber   +3 more
openaire   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Association between plant-based diets and depressive symptoms among Chinese middle-aged and older adults

npj Science of Food
This study aimed to evaluate associations between plant-based diets and the prevalence of depressive symptoms (DepS) among Chinese middle-aged and older adults. This study included 3153 participants aged 45 and older. Dietary intake was collected using a
Li Zhang, Shuai Chen, Lijuan Xu, Sui Tang, Chen Huang, Jin Zhou, Chang-Shu Liu, Sai Wang, Yang Cong, Tingting Li, Liangkai Chen, Wenxue Zhang, Shuang Rong   +12 more
doaj   +1 more source

Association of plant-based food intake in daily diets and hypertension in older adults: a cohort study

Frontiers in Public Health
IntroductionHypertension is a major health concern among older adults, linked to high morbidity and mortality. While plant-based diets may offer health benefits, their association with hypertension in this population remains unclear.
Xiang Wang, Ting Liu, Jianbang Shi, Wei Jie, Miao Dai, Miao Dai   +5 more
doaj   +1 more source

Association between the quality of plant‐based diets and risk of frailty

Journal of Cachexia, Sarcopenia and Muscle, 2022
Background The Mediterranean diet and other dietary patterns rich in fruits and vegetables have been linked to lower risk of frailty in older adults. However, not all plant‐based diets are necessarily healthful, and no previous study has evaluated the ...
Mercedes Sotos‐Prieto, Ellen A. Struijk, Teresa T. Fung, Fernando Rodríguez‐Artalejo, Walter C. Willett, Frank B. Hu, Esther Lopez‐Garcia   +6 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source