Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Molecules, 2016 Protocatechualdehyde (PCA) is an important plant-derived natural product that has been associated with a wide variety of biological activities and has been widely used in medicine as an antioxidant, anti-aging and an anti-inflammatory agent.
Shili Li +5 more
doaj +1 more source
Effectiveness of botanical preparations for the control of rice weevil (Sitophilus oryzae) during rice seed storage and their impact on the rice seed viability : a thesis presented in partial fulfilment of the requirements for the degree of Master of Applied Science in Seed Technology at Massey University, Palmerston North, New Zealand [PDF]
, 2001 Food security and the maintenance of seed quality from harvest to planting are key issues for peasant farmers. In Sierra Leone, up to 28% of rice seed can be damaged by rice weevil in the six months storage period.
Sartie, Alieu Mortuwah
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Frontiers in Microbiology, 2017 Ralstonia solanacearum is one of the most devastating phytopathogens and causes bacterial wilt, which leads to severe economic loss due to its worldwide distribution and broad host range.
Liang Yang +10 more
doaj +1 more source
Plant diversity to support humans in a CELSS ground based demonstrator [PDF]
A controlled ecological life support system (CELSS) for human habitation in preparation for future long duration space flights is considered. The success of such a system depends upon the feasibility of revitalization of food resources and the human ...
Hoff, J. E., Howe, J. M.
core +1 more source
Consumers and consumption of organic food in Central and Eastern European new member states of the European Union [PDF]
, 2007 Despite the significant growth of organic farms and organically managed land in Central and Eastern European new member states of the European Union (CEE NMS) the consumption of organic food in these countries remains at the very low level.
Zakowska-Biemans, S.
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Molecules, 2018 Assessment of two buffered QuEChERS (quick, easy, cheap, effective, rugged, and safe) versions (i.e., citrate and acetate) modified by including methanol to recover the residues of three cyclohexanedione oxime (CHD) herbicides and three of their ...
Juan José Villaverde +4 more
doaj +1 more source
Photosynthesis, CO2 and Plant Production
, 1985 Agricultural production can be increased through better plant characteristics obtained either through breeding or through better growing conditions, both in the soil and above ground. In the chain of events necessary for plant growth, photosynthesis stands at the beginning as the primary conversion of light energy to chemical energy stored in organic ...
Goudriaan, J. +3 more
openaire +3 more sources