Results 81 to 90 of about 543,179 (266)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Processing and Utilization of Functional Substances in Edible Plant Products and the Effects on Health Properties. [PDF]

Foods, 2023
Zeng Z, Yan X.
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Trifluoroacetate leaching potential from fluorinated pesticides: an emission estimation and FOCUS modelling approach

Environmental Sciences Europe
Background Trifluoroacetate (TFA) is a substance of rising concern, because TFA is widespread and high TFA levels have been detected in groundwater, causing an imminent threat, e.g. to organisms in groundwater.
Miriam Diehle, Franziska Schneider, Helena Banning, Christina Heinrich   +3 more
doaj   +1 more source

Recovery, Characterization, Functionality and Applications of Bioactive Compounds from Food-Plant Products and Their By-Products. [PDF]

Plants (Basel), 2023
Fontana A.
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Degradation and sorption of the herbicide pelargonic acid in subsoils below railway tracks compared to a range of topsoils

Environmental Sciences Europe
Background Pelargonic acid is a non-selective herbicide derived from natural sources with a range of potential applications in areas where synthetic herbicides may be less acceptable. One such use area is weed control on railway tracks.
Thomas Poiger, Joanna Müller, Roy Kasteel, Ignaz J. Buerge   +3 more
doaj   +1 more source

Editorial: Plant products for antiviral therapeutics. [PDF]

Front Pharmacol, 2022
Mandal A, Hazra B, Prajapati VK, Moundipa PF.   +3 more
europepmc   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source