Results 61 to 70 of about 4,242,274 (297)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The rhizosphere microbiome and plant health

open access: yes, 2012
The diversity of microbes associated with plant roots is enormous, in the order of tens of thousands of species. This complex plant-associated microbial community, also referred to as the second genome of the plant, is crucial for plant health.
Pieterse, C.M.J.   +4 more
core   +1 more source

Sensory analysis of beans (Phaseolus vulgaris) [PDF]

open access: yesBiotechnologie, Agronomie, Société et Environnement, 1999
The methodology of sensory profiling constitutes the basis of a descriptive quantitative analysis, defining a product with the minimum number of words and with maximum efficiency, using a precise tasting sheet, which can be reproduced and is understood ...
Sanz-Calvo M., Atienza-del-Rey J.
doaj  

Scientific Opinion on the relevance of dissimilar mode of action and its appropriate application for cumulative risk assessment of pesticides residues in food

open access: yesEFSA Journal, 2013
The European Food Safety Authority (EFSA) asked the Panel on Plant Protection Products and their Residues (PPR Panel) to develop a Scientific Opinion on the relevance of dissimilar mode of action and its appropriate application for cumulative risk ...
EFSA Panel on Plant Protection Products and their Residues (PPR)
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Breeding for culinary and nutritional quality of common bean (Phaseolus vulgaris L.) in intercropping systems with maize (Zea mays L.) [PDF]

open access: yesBiotechnologie, Agronomie, Société et Environnement, 1999
Common bean (Phaseolus vulgaris L.) is widely intercropped with maize (Zea mays L.) in the North of Spain. Breeding beans for multiple cropping systems is important for the development of a productive and sustainable agriculture, and is mainly oriented ...
Rodino A.P.   +4 more
doaj  

Guidance for evaluating laboratory and field dissipation studies to obtain DegT50 values of plant protection products in soil

open access: yesEFSA Journal, 2010
The European Commission asked the Panel to revise the Guidance Document on persistence in soil (SANCO/9188VI/1997 of 12 July 2000). Therefore the Panel started the development of a revised methodology for the assessment of exposure of soil organisms ...
EFSA Panel on Plant Protection Products and their Residues (PPR)
doaj   +1 more source

5-Point programme for sustainable plant protection

open access: yesEnvironmental Sciences Europe, 2018
This position paper intends to stimulate a profound rethinking of contemporary agricultural practice. We criticise the current intensity of chemical plant protection in Germany as ecologically unsustainable and thus threatening the achievement of key ...
Tobias Frische   +4 more
doaj   +1 more source

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