Results 41 to 50 of about 563,822 (312)

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel   +3 more
wiley   +1 more source

Guidance on the establishment of the residue definition for dietary risk assessment

open access: yesEFSA Journal, 2016
EFSA has asked the Panel on Plant Protection Products and their Residues to prepare guidance on the establishment of the residue definition for dietary risk assessment.
EFSA Panel on Plant Protection Products and their Residues (PPR)
doaj   +1 more source

Detection of genetically modified plant products by protein strip testing: an evaluation of real-life samples [PDF]

open access: yes, 2007
The determination of the presence of genetically modified plant material by the detection of expressed genetically engineered proteins using lateral flow protein strip tests has been evaluated in different matrices. The presence of five major genetically
CASI, AL   +7 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Effects of increasing fertilization in organic farming fodder cultivation and market crop systems [PDF]

open access: yes, 2007
In 1992, on experimental stations of the Saxony State Institute of Agriculture, two organic field trials were set up on loamy sand and a loess loam in western Saxony, eastern Germany.
Kolbe, Hartmut
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Scientific Opinion on the relevance of dissimilar mode of action and its appropriate application for cumulative risk assessment of pesticides residues in food

open access: yesEFSA Journal, 2013
The European Food Safety Authority (EFSA) asked the Panel on Plant Protection Products and their Residues (PPR Panel) to develop a Scientific Opinion on the relevance of dissimilar mode of action and its appropriate application for cumulative risk ...
EFSA Panel on Plant Protection Products and their Residues (PPR)
doaj   +1 more source

Oral herbal therapies for treating osteoarthritis (review) [PDF]

open access: yes, 2014
Background Medicinal plant products are used orally for treating osteoarthritis. Although their mechanisms of action have not yet been elucidated in full detail, interactions with common inflammatory mediators provide a rationale for using them to ...
Cameron, Melainie, Chrubasik, Sigrun
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Guidance for evaluating laboratory and field dissipation studies to obtain DegT50 values of plant protection products in soil

open access: yesEFSA Journal, 2010
The European Commission asked the Panel to revise the Guidance Document on persistence in soil (SANCO/9188VI/1997 of 12 July 2000). Therefore the Panel started the development of a revised methodology for the assessment of exposure of soil organisms ...
EFSA Panel on Plant Protection Products and their Residues (PPR)
doaj   +1 more source

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