Results 101 to 110 of about 4,242,274 (297)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Plant basal resistance: genetics, biochemistry, and impacts on plant-biotic interactions

open access: yes, 2012
Basal resistance depends largely on a diverse range of defence mechanisms that become active upon attack by pathogens or insects. These mechanisms range from rapid stomatal closure and production of reactive oxygen species, to callose deposition and ...
Ahmad, S.   +2 more
core  

Trifluoroacetate leaching potential from fluorinated pesticides: an emission estimation and FOCUS modelling approach

open access: yesEnvironmental Sciences Europe
Background Trifluoroacetate (TFA) is a substance of rising concern, because TFA is widespread and high TFA levels have been detected in groundwater, causing an imminent threat, e.g. to organisms in groundwater.
Miriam Diehle   +3 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Marketing Efficiency of Dairy Products for Co-operative and Private Dairy Plants in Tamil Nadu - A Comparative Analysis

open access: yes
The marketing of milk and milk products by dairy plants of co-operative and private sectors in Tamil Nadu has been compared. The study is based on the data collected for toned milk, standardized milk, full cream milk, flavoured milk, butter and ghee from
Dhaka, J.P., Rangasamy, N.
core  

Degradation and sorption of the herbicide pelargonic acid in subsoils below railway tracks compared to a range of topsoils

open access: yesEnvironmental Sciences Europe
Background Pelargonic acid is a non-selective herbicide derived from natural sources with a range of potential applications in areas where synthetic herbicides may be less acceptable. One such use area is weed control on railway tracks.
Thomas Poiger   +3 more
doaj   +1 more source

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