Results 91 to 100 of about 1,205 (188)

Cystine knot folding in cyclotides

, 2011
Cyclotides are naturally occurring plant-based proteins of approximately 30 amino acids in size that contain a head-to-tail cyclized backbone and a cystine knot motif formed by their three conserved disulfide bonds. Their exceptional stability and unique
Ulf Göransson, Gruber, Christian W., Norelle L. Daly, David J. Craik, Goransson, Ulf, Daly, Norelle L., Craik, David J., Christian W. Gruber   +7 more
core   +1 more source

Isolation, Characterization, and Bioactivity of Cyclotides from the Micronesian Plant Psychotria leptothyrsa

, 2016
Cyclotides, the largest known family of head-to-tail cyclic peptides, have approximately 30 amino acid residues with a complex structure containing a circular peptide backbone and a cystine knot.
Debasis Mondal (466034), Lars Bohlin (358023), Robert Burman (2206441), Samantha L. Gerlach (2282941), Ulf Göransson (1364202)   +4 more
core   +2 more sources

Overview on the discovery and applications of cyclotides

, 2015
Cyclotides are bioactive peptides from plants that are characterized by their head-to-tail cyclic backbone and knotted arrangement of their three conserved disulfide bonds. Their natural function is thought to be as host defense agents and a single plant
David J. Craik, Craik, David J.
core   +1 more source

Cyclotides in a biotechnological context: opportunities and challenges

, 2015
Plant biotechnology offers us the ability to augment and improve upon biological systems to produce value added crops, medicines, or specialized products.
Mark A. Jackson, Jackson, Mark A., Edward K. Gilding, Gilding, Edward K.   +3 more
core   +1 more source

Cyclotides as tools in chemical biology

, 2017
Conspectus Among the various molecules that plants produce for defense against pests and pathogens, cyclotides stand out as exceptionally stable and structurally unique.
Joachim Weidmann, David J. Craik, de Veer, Simon J., Craik, David J., Simon J. de Veer, Weidmann, Joachim   +5 more
core   +1 more source

Anti-HIV Cyclotides from the Chinese Medicinal Herb Viola yedonensis

, 2008
Cyclotides are macrocyclic plant peptides characterized by a knotted arrangement of three disulfide bonds. They display a range of interesting bioactivities, including anti-HIV and insecticidal activities.
Ireland, David C., Colgrave, Michelle L., Goransson, Ulf, Craik, David J., Gustafson, Kirk R., Wang, Conan K. L.   +5 more
core   +1 more source

Lysine-rich cyclotides: a new subclass of circular knotted proteins from violaceae

, 2015
Cyclotides are macrocyclic proteins produced by plants for host defense. Although, they occur sparsely in other plant cyclotides have been detected in every Violaceae plant species so far screened.
Colgrave, Michelle L., Wang, Conan K., David J. Craik (13753), Aaron G. Poth (1478464), Michelle L. Colgrave (368112), Craik, David J., Anjaneya S. Ravipati (1478467), Poth, Aaron G., Sónia Troeira Henriques (1430581), Conan K. Wang (198148), Kaas, Quentin, Ravipati, Anjaneya S., Quentin Kaas (26864), Henriques, Sónia Troeira   +13 more
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Behavioral and physiological effects of Viola spp. cyclotides on Myzus persicae (Sulz.)

, 2020
Cyclotides are defense peptides produced by several plant families. Viola spp. (Violaceae) produce an array of cyclotides with varying biological activities.
Dancewicz, Katarzyna, Gabrys, Beata, Kielkiewicz, Malgorzata, Bohdanowicz, Jerzy, Slazak, Blazej, Kapusta, Malgorzata   +5 more
core   +1 more source

Discovery and Characterization of Cyclotides from Rinorea Species

, 2018
Cyclotides are macrocyclic cystine-knotted peptides most commonly found in the Violaceae plant family. Although Rinorea is the second-largest genera within the Violaceae family, few studies have examined whether or not they contain cyclotides. To further
Lai Yue Chan (468091), Michelle L. Colgrave, Ploypat Niyomploy, Peta J. Harvey (780811), Lai Yue Chan, David J. Craik, David J. Craik (13753), Aaron G. Poth (1478464), Michelle L. Colgrave (368112), Peta J. Harvey, Ploypat Niyomploy (5923709), Aaron G. Poth   +11 more
core   +1 more source

Discovery and characterization of cyclotides from Rinorea species

, 2018
Cyclotides are macrocyclic cystine-knotted peptides most commonly found in the Violaceae plant family. Although Rinorea is the second-largest genera within the Violaceae family, few studies have examined whether or not they contain cyclotides. To further
Harvey, Peta J., Colgrave, Michelle L., Niyomploy, Ploypat, Chan, Lai Yue, Craik, David J., Poth, Aaron G.   +5 more
core   +1 more source