PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers. [PDF]
, 2019 Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for
Shams, Shahin +3 more
core +1 more source
Aminoglycoside-Induced Phosphatidylserine Externalization in Sensory Hair Cells Is Regionally Restricted, Rapid, and Reversible [PDF]
, 2008 The aminophospholipid phosphatidylserine (PS) is normally restricted to the inner leaflet of the plasma membrane. During certain cellular processes, including apoptosis, PS translocates to the outer leaflet and can be labeled with externally applied ...
Gale, Jonathan E +4 more
core +1 more source
Structural variants of biodegradable polyesterurethane in vivo evoke a cellular and angiogenic response that is dictated by architecture [PDF]
, 2009 This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2008 Acta Materialia Inc.The aim of this study was to investigate an in vivo tissue response to a biodegradable polyesterurethane ...
Burugapalli, K +3 more
core +1 more source
Frontiers in Microbiology, 2021 Staphylococcus aureus (S. aureus) is well known to express a plethora of toxins of which the pore-forming hemolysin A (α-toxin) is the best-studied cytolysin.
David Krones +8 more
doaj +1 more source
A potential role for Dkk-1 in the pathogenesis of osteosarcoma predicts novel diagnostic and treatment strategies. [PDF]
, 2007 Canonical Wnt signaling is an osteo-inductive signal that promotes bone repair through acceleration of osteogenic differentiation by progenitors. Dkk-1 is a secreted inhibitor of canonical Wnt signaling and thus inhibits osteogenesis.
Angela Smolarz +9 more
core +3 more sources
TREM1/3 deficiency impairs tissue repair after acute kidney injury and mitochondrial metabolic flexibility in tubular epithelial cells [PDF]
, 2019 Long-term sequelae of acute kidney injury (AKI) are associated with incomplete recovery of renal function and the development of chronic kidney disease (CKD), which can be mediated by aberrant innate immune activation, mitochondrial pathology, and ...
Borrelli, Cristiana +10 more
core +2 more sources
Hydraulic fracturing in cells and tissues: fracking meets cell biology [PDF]
, 2017 The animal body is fundamentally made of water. A small fraction of this water is freely flowing in blood and lymph, but most of it is trapped in hydrogels such as the extracellular matrix (ECM), the cytoskeleton, and chromatin.
Arroyo Balaguer, Marino +1 more
core +4 more sources
Into the breach: how cells cope with wounds [PDF]
Open Biology, 2018 Repair of wounds to individual cells is crucial for organisms to survive daily physiological or environmental stresses, as well as pathogen assaults, which disrupt the plasma membrane.
Mitsutoshi Nakamura +5 more
doaj +1 more source
Biology Open, 2018 Endocytic mechanisms have been suggested to be important for plasma membrane repair in response to pore-forming toxins such as listeriolysin O (LLO), which form membrane pores that disrupt cellular homeostasis.
Lars Nygård Skalman +3 more
doaj +1 more source
The SNARE complex formed by RIC-4/SEC-22/SYX-2 promotes C. elegans epidermal wound healing
Cell Reports, 2023 Summary: Maintaining cellular viability relies on the integrity of the plasma membrane, which must be repaired upon damage. Soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE)-mediated membrane fusion is a crucial mechanism ...
Qingfang Shao +6 more
doaj +1 more source