Results 41 to 50 of about 165,729 (227)
A new twist on plasma membrane repair [PDF]
Communicative & Integrative Biology, 2011 Cells in multicellular organisms are under constant mechanical stress, and often the plasma membrane (PM) is compromised. Fortunately, there is a vigorous repair mechanism that rapidly (within seconds) reseals the wound site by fusion with an internal membrane patch.
openaire +2 more sources
Into the breach: how cells cope with wounds [PDF]
Open Biology, 2018 Repair of wounds to individual cells is crucial for organisms to survive daily physiological or environmental stresses, as well as pathogen assaults, which disrupt the plasma membrane.
Mitsutoshi Nakamura +5 more
doaj +1 more source
Biology Open, 2018 Endocytic mechanisms have been suggested to be important for plasma membrane repair in response to pore-forming toxins such as listeriolysin O (LLO), which form membrane pores that disrupt cellular homeostasis.
Lars Nygård Skalman +3 more
doaj +1 more source
BiomoleculesAlzheimer’s Disease (AD) is the most common neurodegenerative disease that involves neuronal cell death initiated by the breakdown of the plasma membrane.
Hannah R. Bulgart +2 more
doaj +1 more source
The SNARE complex formed by RIC-4/SEC-22/SYX-2 promotes C. elegans epidermal wound healing
Cell Reports, 2023 Summary: Maintaining cellular viability relies on the integrity of the plasma membrane, which must be repaired upon damage. Soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE)-mediated membrane fusion is a crucial mechanism ...
Qingfang Shao +6 more
doaj +1 more source
Defective membrane repair machinery impairs survival of invasive cancer cells
Scientific Reports, 2020 Cancer cells are able to reach distant tissues by migration and invasion processes. Enhanced ability to cope with physical stresses leading to cell membrane damages may offer to cancer cells high survival rate during metastasis.
F. Bouvet +7 more
doaj +1 more source
Repair of injured plasma membrane by rapid Ca2+-dependent endocytosis [PDF]
The Journal of Cell Biology, 2008 Ca2+ influx through plasma membrane lesions triggers a rapid repair process that was previously shown to require the exocytosis of lysosomal organelles (Reddy, A., E. Caler, and N. Andrews. 2001. Cell. 106:157–169). However, how exocytosis leads to membrane resealing has remained obscure, particularly for stable lesions caused by pore-forming proteins.
Idone, Vincent +5 more
openaire +2 more sources
Mechanisms of Endothelial Cell Membrane Repair: Progress and Perspectives
Cells, 2023 Endothelial cells are the crucial inner lining of blood vessels, which are pivotal in vascular homeostasis and integrity. However, these cells are perpetually subjected to a myriad of mechanical, chemical, and biological stresses that can compromise ...
Duoduo Zha +5 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Muscle membrane repair and inflammatory attack in dysferlinopathy
Skeletal Muscle, 2011 Repair of plasma membrane tears is an important normal physiological process that enables the cells to survive a variety of physiological and pathological membrane lesions.
Han Renzhi
doaj +1 more source