Results 21 to 30 of about 3,013,542 (232)
iScience, 2021 Summary: The plasma membrane repair holds significance for maintaining cell survival and homeostasis. To achieve the sensitive visualization of membrane repair process for revealing its mechanism, this work designs a perforation-induced surface-enhanced ...
Yuanjiao Yang +4 more
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Frontiers in Cell and Developmental Biology, 2022 After damage, cells repair their plasma membrane in an active process that is driven by Ca2+ entering through the wound. This triggers a range of Ca2+-regulated events such as the translocation of different Ca2+-binding proteins to the wound site which ...
Arsila P. K. Ashraf, Volker Gerke
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The road not taken: Less traveled roads from the TGN to the plasma membrane [PDF]
, 2015 : The trans-Golgi network functions in the distribution of cargo into different transport vesicles that are destined to endosomes, lysosomes and the plasma membrane. Over the years, it has become clear that more than one transport pathway promotes plasma
Anne Spang, Spang, Anne, Spang A
core +1 more source
Requirement for Annexin A1 in Plasma Membrane Repair [PDF]
Journal of Biological Chemistry, 2006 Ca2+ entering a cell through a torn or disrupted plasma membrane rapidly triggers a combination of homotypic and exocytotic membrane fusion events. These events serve to erect a reparative membrane patch and then anneal it to the defect site. Annexin A1 is a cytosolic protein that, when activated by micromolar Ca2+, binds to membrane phospholipids ...
Anna K, McNeil +3 more
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Pathogenesis of Multiple Organ Failure: The Impact of Systemic Damage to Plasma Membranes
Frontiers in Medicine, 2022 Multiple organ failure (MOF) is the major cause of morbidity and mortality in intensive care patients, but the mechanisms causing this severe syndrome are still poorly understood.
Andrey V. Kozlov +5 more
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Plasma Membrane Repair in Health and Disease [PDF]
, 2016 Since an intact membrane is required for normal cellular homeostasis, membrane repair is essential for cell survival. Human genetic studies, combined with the development of novel animal models and refinement of techniques to study cellular injury, have now uncovered series of repair proteins highly relevant for human health.
Alexis R, Demonbreun +1 more
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Plasma membrane wounding and repair in pulmonary diseases [PDF]
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2017 Various pathophysiological conditions such as surfactant dysfunction, mechanical ventilation, inflammation, pathogen products, environmental exposures, and gastric acid aspiration stress lung cells, and the compromise of plasma membranes occurs as a result.
Xiaofei, Cong +3 more
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Early Endosomes Act as Local Exocytosis Hubs to Repair Endothelial Membrane Damage
Advanced Science, 2023 The plasma membrane of a cell is subject to stresses causing ruptures that must be repaired immediately to preserve membrane integrity and ensure cell survival.
Nikita Raj +9 more
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Promotion of plasma membrane repair by vitamin E [PDF]
Nature Communications, 2011 Severe vitamin E deficiency results in lethal myopathy in animal models. Membrane repair is an important myocyte response to plasma membrane disruption injury as when repair fails, myocytes die and muscular dystrophy ensues. Here we show that supplementation of cultured cells with α-tocopherol, the most common form of vitamin E, promotes plasma ...
Howard, Amber Cyran +2 more
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Plasma membrane repairs by small GTPase Rab3a [PDF]
Journal of Cell Biology, 2016 Lysosomes fuse with the plasma membrane to help repair membrane lesions, but how they are positioned close to these lesions is not fully understood. Now, Encarnação et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201511093) demonstrate that the lysosomal GTPase Rab3a and its effectors orchestrate lysosome positioning and plasma membrane ...
Camilla Raiborg, Harald Stenmark
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