Results 11 to 20 of about 173,214 (234)
Cellular mechanisms and signals that coordinate plasma membrane repair [PDF]
Cellular and Molecular Life Sciences, 2018 Plasma membrane forms the barrier between the cytoplasm and the environment. Cells constantly and selectively transport molecules across their plasma membrane without disrupting it. Any disruption in the plasma membrane compromises its selective permeability and is lethal, if not rapidly repaired.
Adam Horn +2 more
exaly +5 more sources
Structural and signaling role of lipids in plasma membrane repair [PDF]
Current Topics in Membranes, 2019 The plasma membrane forms the physical barrier between the cytoplasm and extracellular space, allowing for biochemical reactions necessary for life to occur. Plasma membrane damage needs to be rapidly repaired to avoid cell death. This relies upon the coordinated action of the machinery that polarizes the repair response to the site of injury ...
Adam Horn, Jyoti K Jaiswal
exaly +5 more sources
Plasma Membrane Wounding and Repair Assays for Eukaryotic Cells
Bio-Protocol, 2022 Damage to the plasma membrane and loss of membrane integrity are detrimental to eukaryotic cells. It is, therefore, essential that cells possess an efficient membrane repair system to survive.
Stine Sønder +4 more
doaj +4 more sources
Rab3a and Rab10 are regulators of lysosome exocytosis and plasma membrane repair [PDF]
Small GTPases, 2018 Disruption of the cell plasma membrane can occur due to mechanical damage, pore forming toxins, etc. Resealing or plasma membrane repair (PMR) is the emergency response required for cell survival. It is triggered by Ca2+ entering through the disruption, causing organelles such as lysosomes located underneath the plasma membrane to fuse rapidly with the
Vieira O
exaly +5 more sources
LAMP-2 absence interferes with plasma membrane repair and decreases T. cruzi host cell invasion. [PDF]
PLoS Neglected Tropical Diseases, 2017 Trypanosoma cruzi enters host cells by subverting the mechanism of cell membrane repair. In this process, the parasite induces small injuries in the host cell membrane leading to calcium entry and lysosomal exocytosis, which are followed by compensatory ...
Natália Fernanda Couto +9 more
doaj +2 more sources
Plasma membrane damage caused by listeriolysin O is not repaired through endocytosis of the membrane pore [PDF]
Biology Open, 2018 Endocytic mechanisms have been suggested to be important for plasma membrane repair in response to pore-forming toxins such as listeriolysin O (LLO), which form membrane pores that disrupt cellular homeostasis.
Lars Nygård Skalman +3 more
doaj +4 more sources
Plasma Membrane Repair in Health and Disease. [PDF]
Curr Top Membr, 2016 Since an intact membrane is required for normal cellular homeostasis, membrane repair is essential for cell survival. Human genetic studies, combined with the development of novel animal models and refinement of techniques to study cellular injury, have now uncovered series of repair proteins highly relevant for human health.
Demonbreun AR, McNally EM.
europepmc +4 more sources
Current Biology, 2018 Tissue wound repair has been studied extensively. It involves the coordinated activation of several intracellular and intercellular pathways, as well as remodeling from the sequential recruitment of different cell types to the wound site. There is, however, an equally important process that happens at the single cell level, when the integrity of the ...
Norma W, Andrews, Matthias, Corrotte
openaire +2 more sources
Plasma membrane integrity in health and disease: significance and therapeutic potential
Cell Discovery, 2021 Maintenance of plasma membrane integrity is essential for normal cell viability and function. Thus, robust membrane repair mechanisms have evolved to counteract the eminent threat of a torn plasma membrane.
Catarina Dias, Jesper Nylandsted
doaj +1 more source
Lectin-based food poisoning: a new mechanism of protein toxicity. [PDF]
PLoS ONE, 2007 BACKGROUND: Ingestion of the lectins present in certain improperly cooked vegetables can result in acute GI tract distress, but the mechanism of toxicity is unknown.
Katsuya Miyake +2 more
doaj +1 more source