Results 31 to 40 of about 3,013,542 (232)
Repurposing phenothiazines for cancer therapy: compromising membrane integrity in cancer cells
Frontiers in Oncology, 2023 The limitations of current cancer therapies, including the increasing prevalence of multidrug resistance, underscore the urgency for more effective treatments. One promising avenue lies in the repurposing of existing drugs.
Syrina Fred Mehrabi +3 more
doaj +1 more source
A new twist on plasma membrane repair [PDF]
Communicative & Integrative Biology, 2011 Cells in multicellular organisms are under constant mechanical stress, and often the plasma membrane (PM) is compromised. Fortunately, there is a vigorous repair mechanism that rapidly (within seconds) reseals the wound site by fusion with an internal membrane patch.
openaire +2 more sources
Plasma membrane compartmentation in Saccharomyces cerevisiae [PDF]
, 2009 In the plasma membrane of cells the complex variety of components is sorted into subcompartments, microdomains and nanoclusters. We only begin to understand the principles of this higher order.
Großmann, Guido
core +1 more source
Two-way traffic on the road to plasma membrane repair [PDF]
Trends in Cell Biology, 2008 Ca(2+) influx through plasma membrane wounds triggers a rapid-repair response that is essential for cell survival. Earlier studies showed that repair requires the exocytosis of intracellular vesicles. Exocytosis was thought to promote resealing by 'patching' the plasma membrane lesion or by facilitating bilayer restoration through reduction in membrane
Vincent, Idone +2 more
openaire +2 more sources
Microscopic simulation of membrane molecule diffusion on corralled membrane surfaces [PDF]
, 2008 The current understanding of how receptors diffuse and cluster in the plasma membrane is limited. Data from single-particle tracking and laser tweezer experiments have suggested that membrane molecule diffusion is affected by the presence of barriers ...
Edwards, Jeremy S. +4 more
core +1 more source
Damage control: cellular mechanisms of plasma membrane repair [PDF]
Trends in Cell Biology, 2014 When wounded, eukaryotic cells reseal in a few seconds. Ca(2+) influx induces exocytosis of lysosomes, a process previously thought to promote repair by 'patching' wounds. New evidence suggests that resealing involves direct wound removal. Exocytosis of lysosomal acid sphingomyelinase (ASM) triggers endocytosis of lesions followed by intracellular ...
Norma W, Andrews +2 more
openaire +2 more sources
Frontiers in Microbiology, 2021 Staphylococcus aureus (S. aureus) is well known to express a plethora of toxins of which the pore-forming hemolysin A (α-toxin) is the best-studied cytolysin.
David Krones +8 more
doaj +1 more source
Effect of Antarctic Krill Oil Supplementation on Skeletal Muscle Plasma Membrane Repair in Mice after Exhaustive Exercise [PDF]
Shipin Kexue, 2023 Objective: To investigate the effects of supplementation of Antarctic krill oil (KO) on muscle plasma membrane injury and functional recovery in mice after exhaustive exercise, and to explore the possible mechanism by which KO supplementation promotes ...
YANG Simeng, HE Qing, SHI Lijun, WU Ying
doaj +1 more source
BiomoleculesAlzheimer’s Disease (AD) is the most common neurodegenerative disease that involves neuronal cell death initiated by the breakdown of the plasma membrane.
Hannah R. Bulgart +2 more
doaj +1 more source
Caveolae biogenesis and lipid sorting at the plasma membrane
, 2022 The plasma membrane of many cell types, in particular, endothelia, smooth muscle cells, and adipocytes, contains numerous small invaginations termed caveolae.
Hubert, Madlen, +3 more
core +1 more source