HID-1 controls formation of large dense core vesicles by influencing cargo sorting and trans-Golgi network acidification [PDF]
, 2017 Large dense core vesicles (LDCVs) mediate the regulated release of neuropeptides and peptide hormones. They form at the trans-Golgi network (TGN), where their soluble content aggregates to form a dense core, but the mechanisms controlling biogenesis are ...
Asensio, Cedric S +7 more
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So far, yet so close: α-Catenin dimers help migrating cells get together [PDF]
, 2017 Epithelial cells in tissues use their actin cytoskeletons to stick together, whereas unattached cells make active plasma membrane protrusions to migrate. In this issue, Wood et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201612006) show that the
Benjamin +12 more
core +2 more sources
Connexin communication compartments and wound repair in epithelial tissue [PDF]
, 2018 Epithelial tissues line the lumen of tracts and ducts connecting to the external environment. They are critical in forming an interface between the internal and external environment and, following assault from environmental factors and pathogens, they ...
Chanson, Marc +4 more
core +7 more sources
BiomoleculesAlzheimer’s Disease (AD) is the most common neurodegenerative disease that involves neuronal cell death initiated by the breakdown of the plasma membrane.
Hannah R. Bulgart +2 more
doaj +1 more source
The development of a ε-polycaprolactone (PCL) scaffold for CNS repair [PDF]
, 2012 Potential treatment strategies for the repair of spinal cord injury (SCI) currently favour a combinatorial approach incorporating several factors, including exogenous cell transplantation and biocompatible scaffolds. The use of scaffolds for bridging the
Gelain F. +9 more
core +1 more source
Gene Expression in Experimental Aortic Coarctation and Repair: Candidate Genes for Therapeutic Intervention? [PDF]
, 2015 Coarctation of the aorta (CoA) is a constriction of the proximal descending thoracic aorta and is one of the most common congenital cardiovascular defects.
Bozdag, Serdar +5 more
core +9 more sources
Defective membrane repair machinery impairs survival of invasive cancer cells
Scientific Reports, 2020 Cancer cells are able to reach distant tissues by migration and invasion processes. Enhanced ability to cope with physical stresses leading to cell membrane damages may offer to cancer cells high survival rate during metastasis.
F. Bouvet +7 more
doaj +1 more source
Mechanisms of Endothelial Cell Membrane Repair: Progress and Perspectives
Cells, 2023 Endothelial cells are the crucial inner lining of blood vessels, which are pivotal in vascular homeostasis and integrity. However, these cells are perpetually subjected to a myriad of mechanical, chemical, and biological stresses that can compromise ...
Duoduo Zha +5 more
doaj +1 more source
Spatial Organization of the Cytoskeleton enhances Cargo Delivery to Specific Target Areas on the Plasma Membrane of Spherical Cells [PDF]
, 2016 Intracellular transport is vital for the proper functioning and survival of a cell. Cargo (proteins, vesicles, organelles, etc.) is transferred from its place of creation to its target locations via molecular motor assisted transport along cytoskeletal ...
Hafner, Anne E., Rieger, Heiko
core +2 more sources
Laser-assisted photoporation : fundamentals, technological advances and applications [PDF]
, 2016 Laser-assisted photoporation is a promising technique that is receiving increasing attention for the delivery of membrane impermeable nanoscopic substances into living cells.
Braeckmans, Kevin +5 more
core +1 more source