Results 1 to 10 of about 64,860 (240)

Human Plasmacytoid Dendritic Cells and Cutaneous Melanoma [PDF]

Cells, 2020
The prognosis of metastatic melanoma (MM) patients has remained poor for a long time. However, the recent introduction of effective target therapies (BRAF and MEK inhibitors for BRAFV600-mutated MM) and immunotherapies (anti-CTLA-4 and anti-PD-1) has ...
Matilde Monti, Francesca Consoli, Raffaella Vescovi, Mattia Bugatti, William Vermi   +4 more
doaj   +3 more sources

Proliferation of CD10+ mature plasmacytoid dendritic cells in lymph nodes of patients with chronic non-tuberculous mycobacterial infection: a case report [PDF]

Journal of Medical Case Reports
Background Plasmacytoid dendritic cells are essential immune system components, critical in antiviral and antibacterial defense. Although plasmacytoid dendritic cells are typically present in small numbers in the peripheral blood, bone marrow, and lymph ...
Longyi Zhang, Jinwen Jiang, Xuya Chen, Yingqian Sun, Yan Lu   +4 more
doaj   +2 more sources

Role of plasmacytoid dendritic cells in vascular dysfunction in mice with renovascular hypertension [PDF]

Heliyon
Endothelial dysfunction and inflammation are clinically significant risk factors for cardiovascular diseases in hypertension. Although immune cells play a role in hypertension, the impact of plasmacytoid dendritic cells in established renovascular ...
Balaji Srinivas, Kiran Alluri, Nour-Eddine Rhaleb, Souad Belmadani, Khalid Matrougui   +4 more
doaj   +2 more sources

Distinct metabolic profiles of circulating plasmacytoid dendritic cells in systemic sclerosis patients stratified by clinical phenotypes [PDF]

Arthritis Research & Therapy
Background Plasmacytoid dendritic cells (pDCs) play a key role in systemic sclerosis (SSc) pathophysiology. However, despite the recognised importance of metabolic reprogramming for pDC function, their metabolic profile in SSc remains to be elucidated ...
Beatriz H. Ferreira, Carolina Mazeda, Eduardo Dourado, João L. Simões, Ana Rita Prata, Rafael J. Argüello, Iola F. Duarte, Philippe Pierre, Catarina R. Almeida   +8 more
doaj   +2 more sources

Skin TLR7 triggering promotes accumulation of respiratory dendritic cells and natural killer cells. [PDF]

, 2012
The TLR7 agonist imiquimod has been used successfully as adjuvant for skin treatment of virus-associated warts and basal cell carcinoma. The effects of skin TLR7 triggering on respiratory leukocyte populations are unknown.
Baal, Nelli, Bein, Gregor, Gruber, Achim D., Hackstein, Holger, Hagel, Nicole, Kershaw, Olivia, Knoche, Angela, Kranz, Sabine, Lohmeyer, Jürgen, Wulffen, Werner von   +9 more
core   +18 more sources

T Lymphoblastic Lymphoma Hiding in Mature Plasmacytoid Dendritic Cell Proliferation: A Case Report and Literature Review

Diagnostics, 2023
To the best of the author’s knowledge, studies of mature plasmacytoid dendritic cell proliferation associated with T lymphoblastic lymphoma were extremely rare in the literature.
Cong Deng, Beibei Gao, Tianli Wang, Xiaona Chang, Guixiang Xiao, Qin Xia, Huaxiong Pan, Xiu Nie   +7 more
doaj   +1 more source

Different distribution patterns of plasmacytoid dendritic cells in discoid lupus erythematosus and lichen planopilaris demonstrated by CD123 immunostaining, [PDF]

Anais Brasileiros de Dermatologia, 2020
Background: Clinical and histological features may overlap between lichen planopilaris-associated and discoid lupus erythematosus-associated scarring alopecia.
Azadeh Rakhshan, Parviz Toossi, Maliheh Amani, Sahar Dadkhahfar, Arash Bagheri Hamidi   +4 more
doaj   +1 more source

Rapidly progressing blastic plasmacytoid dendritic cell neoplasm causing diffuse skin thickening: A case report with sequential computed tomography examinations

Radiology Case Reports, 2021
Blastic plasmacytoid dendritic cell neoplasm is a rare aggressive myeloid malignancy thought to be derived from precursor plasmacytoid dendritic cells. Rapid progression and poor prognosis have been known.
Kyohei Yoshioka, Ryo Kurokawa, Shiori Amemiya, Hiroaki Koyamaa, Kensuke Matsuda, Akira Honda, Mineo Kurokawa, Aya Shinozaki-Ushiku, Osamu Abe   +8 more
doaj   +1 more source

Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells

Nature Communications, 2022
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and highly aggressive hematologic malignancy derived from the precursors of plasmacytoid dendritic cells.
Tianyu Cai, Agnès Gouble, Kathryn L. Black, Anna Skwarska, Ammar S. Naqvi, Deanne Taylor, Ming Zhao, Qi Yuan, Mayumi Sugita, Qi Zhang, Roman Galetto, Stéphanie Filipe, Antonio Cavazos, Lina Han, Vinitha Kuruvilla, Helen Ma, Connie Weng, Chang-Gong Liu, Xiuping Liu, Sergej Konoplev, Jun Gu, Guilin Tang, Xiaoping Su, Gheath Al-Atrash, Stefan Ciurea, Sattva S. Neelapu, Andrew A. Lane, Hagop Kantarjian, Monica L. Guzman, Naveen Pemmaraju, Julianne Smith, Andrei Thomas-Tikhonenko, Marina Konopleva   +32 more
doaj   +1 more source

ChemR23 dampens lung inflammation and enhances anti-viral immunity in a mouse model of acute viral pneumonia. [PDF]

PLoS Pathogens, 2011
Viral diseases of the respiratory tract, which include influenza pandemic, children acute bronchiolitis, and viral pneumonia of the elderly, represent major health problems.
Benjamin Bondue, Olivier Vosters, Patricia de Nadai, Stéphanie Glineur, Olivier De Henau, Souphalone Luangsay, Frédéric Van Gool, David Communi, Paul De Vuyst, Daniel Desmecht, Marc Parmentier   +10 more
doaj   +1 more source