Results 181 to 190 of about 40,172 (208)
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Blastic Plasmacytoid Dendritic Cell Neoplasm
Current Treatment Options in Oncology, 2019While there is a high initial response rate with standard chemotherapeutic regimens for blastic plasmacytoid dendritic cell neoplasm (BPDCN), the responses are typically not durable and this remains a very aggressive disease with generally poor outcomes.
Daniel, Kerr +2 more
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Plasmacytoid dendritic cells in cutaneous sarcoidosis.
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2018While absent from normal skin, plasmacytoid dendritic cells (pDCs) infiltrate the skin in several infectious, inflammatory, and neoplastic entities. In addition to providing anti-viral resistance, pDCs link the innate and adaptive immune responses. Sarcoidosis is an idiopathic multi-system granulomatous disease characterized by epitheliod granulomas ...
Halawi, Ali +2 more
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Plasmacytoid dendritic cells and autoimmune inflammation
bchm, 2013Abstract Plasmacytoid dendritic cells (pDC) are a sub-population of dendritic cells (DC) that produce large amounts of type I interferon (IFN) in response to nucleic acids that bind and activate toll-like-receptor (TLR)9 and TLR7. Type I IFN can regulate the function of B, T, DC, and natural killer (NK) cells and can also alter the ...
Georgina, Galicia, Jennifer L, Gommerman
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Plasmacytoid dendritic cell in immunity and cancer
Journal of Neuroimmunology, 2018Plasmacytoid dendritic cells (pDCs) comprise a subset of dendritic cells characterized by their ability to produce large amount of type I interferon (IFN-I/α). Originally recognized for their role in modulating immune responses to viral stimulation, growing interest has been directed toward their contribution to tumorigenesis.
Dana, Mitchell +2 more
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The multifaceted murine plasmacytoid dendritic cell
Human Immunology, 2002Plasmacytoid dendritic cells (PDCs) or natural interferon-producing cells, function as the body's innate defense against viral infections. As discussed here, they may play additional roles in response to bacterial pathogens and may have the capacity to induce different type of T-cell responses depending on what signals they receive.
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Reclassification of plasmacytoid dendritic cells as innate lymphocytes is premature
Nature Reviews Immunology, 2023Marco Colonna +2 more
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Reply to ‘Reclassification of plasmacytoid dendritic cells as innate lymphocytes is premature’
Nature Reviews Immunology, 2023Florent Ginhoux +2 more
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Reclassifying plasmacytoid dendritic cells as innate lymphocytes
Nature Reviews Immunology, 2022Florent Ginhoux +2 more
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Clonal lineage tracing reveals shared origin of conventional and plasmacytoid dendritic cells
Immunity, 2022Nicholas Adams +2 more
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Plasmacytoid dendritic cells turn red!
Nature Immunology, 2023Roxane Tussiwand, Tussiwand Roxane
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