Results 191 to 200 of about 45,338 (267)

The Role of Plasmacytoid Dendritic Cells in the Immune Contexture of <i>TP53</i>-Mutated High-Grade Serous Ovarian Cancer. [PDF]

Cancers (Basel)
Steger K, Fiegl H, Rungger K, Leitner K, Tsibulak I, Feroz B, Ebner C, Marth C, Hackl H, Zeimet AG.   +9 more
europepmc   +1 more source

Mitochondrial DNA: A Key Alarmin Igniting the Inflammasome Fire in Health and Disease

Immunology, Volume 178, Issue 2, Page 218-230, June 2026.
This review illustrates how mitochondrial DNA, released under cellular stress, acts as a key alarmin that ignites innate immune sensors, particularly inflammasomes and the cGAS‐STING pathway. This paper details how this sustained “inflammasome fire” fuels the progression of diverse inflammatory diseases, including neurodegeneration and metabolic ...
Woo Hyun Park
wiley   +1 more source

Publisher Correction: TNF and type I interferon crosstalk controls the fate and function of plasmacytoid dendritic cells. [PDF]

Nat Immunol
Arroyo Hornero R, Maqueda-Alfaro RA, Solís-Barbosa MA, Leylek RA, Medina Chavez O, Martinez OM, Gottfried-Blackmore A, Idoyaga J.   +7 more
europepmc   +1 more source

Plasmacytoid dendritic cells contribute to vascular endothelial dysfunction in type 2 diabetes. [PDF]

Front Cardiovasc Med, 2023
Alluri K, Srinivas B, Belmadani S, Matrougui K.   +3 more
europepmc   +1 more source

Diabetes and Delayed Wound Healing: Molecular Mechanisms and Dermatological Interventions

International Wound Journal, Volume 23, Issue 6, June 2026.
ABSTRACT Diabetes mellitus is a global burden that affects wound healing at nearly every stage, transforming what should be a coordinated and self‐limited repair process into a chronic, non‐healing state. In diabetic patients, sustained hyperglycemia drives persistent inflammation, impaired angiogenesis, fibroblast dysfunction and extracellular matrix ...
Sasha Jreije, Marwan Fadel, Carl Karam, Hilda E. Ghadieh, Antoine Ghanem   +4 more
wiley   +1 more source

Targeting Siglec-sialic acid checkpoint to reverse immune dysfunction mediated by plasmacytoid dendritic cells in myeloma. [PDF]

Blood Adv
Ray A, Buon L, Wan X, Du T, Song Y, Pillai SC, Musa MA, Fang T, Wang M, Anderson KC.   +9 more
europepmc   +1 more source

Immune Landscape and Tumour Heterogeneity in Ovarian Cancer: Insights From Single‐Cell RNA Sequencing

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Tumour heterogeneity is a key factor in cancer progression, with immune responses within the tumour microenvironment (TME) contributing significantly to treatment resistance and immunotherapy outcomes. Recent advances in single‐cell RNA sequencing (scRNA‐seq) have provided unprecedented insights into the diverse immune cell populations ...
Sihan Chen, Ghada Moh. Samir Elhessewi, Helen Cai, Wedad M. Alawad, Manoj Kumar Mishra, Usamah Sayed   +5 more
wiley   +1 more source

Plasmacytoid dendritic cells are dispensable or detrimental in murine systemic or respiratory viral infections. [PDF]

Nat Immunol
Ngo C, Pierini-Malosse C, Rahmani K, Valente M, Collinet N, Bessou G, Guerry C, Fabregue M, Mathieu S, Sharkaoui S, Mazzoli S, Sansoni A, Fiore F, Laprie C, Alexopoulou L, Gaya M, Gregoire C, Broggi A, Wurbel S, Rua R, Haidar N, Milpied P, Escalière B, Vu Manh TP, Fallet M, Chasson L, Tran H, Baranek T, Le Bert M, Malissen B, Zarubica A, Dalod M, Tomasello E.   +32 more
europepmc   +1 more source

Novel immunotherapy for multiple myeloma involving activation of plasmacytoid dendritic cells. [PDF]

Mol Ther Oncol
Kurimoto M, Watanabe T, Kudo M.
europepmc   +1 more source

Tonic type I interferon signaling optimizes the antiviral function of plasmacytoid dendritic cells. [PDF]

Nat Immunol
Pucella JN, Maqueda-Alfaro RA, Ni H, Bandeira Sulczewski F, Eichinger A, Esteva E, Ra AC, Das A, Perez OA, Feng J, Stoeckius M, Smibert P, Khodadadi-Jamayran A, Dolgalev I, Ivanova E, Sota S, Cadwell K, Koralov SB, Zhong J, Soni C, Stetson DB, Weisberg SP, Farber DL, Idoyaga J, Reizis B.   +24 more
europepmc   +1 more source