Mapping malignant T‐cell states and immune circuits in Sézary syndrome by single‐cell analysis
Peripheral blood single‐cell RNA‐seq from leukaemic CTCL defined three malignant T‐cell programmes: MTC CM, MTC Reg and MTC E/EM, each with distinct features and candidate vulnerabilities. For example, inferred immune circuits highlighted actionable IL‐10/JAK–TYK2–STAT3 signalling, KIR–MHC I inhibitory interactions and myeloid/B‐cell inflammatory and ...
Beth A. Childs +6 more
wiley +1 more source
Natural Interferon-α Producing Cells: The Plasmacytoid Dendritic Cells
Patricia Fitzgerald-Bocarsly
doaj +1 more source
Targeting Siglec-sialic acid checkpoint to reverse immune dysfunction mediated by plasmacytoid dendritic cells in myeloma. [PDF]
Ray A +9 more
europepmc +1 more source
Plasmacytoid dendritic cells are dispensable or detrimental in murine systemic or respiratory viral infections. [PDF]
Ngo C +32 more
europepmc +1 more source
Novel immunotherapy for multiple myeloma involving activation of plasmacytoid dendritic cells. [PDF]
Kurimoto M, Watanabe T, Kudo M.
europepmc +1 more source
Tonic type I interferon signaling optimizes the antiviral function of plasmacytoid dendritic cells. [PDF]
Pucella JN +24 more
europepmc +1 more source
Metabolite derived from green tea polyphenol increases and activates plasmacytoid dendritic cells. [PDF]
Kumazoe M +7 more
europepmc +1 more source
Efficacy and Long-Term Remission Following Haploidentical HSCT for Therapy-Related Acute Myelomonocytic Leukemia with Plasmacytoid Dendritic Cells Post-FCR Therapy for CLL: A Case Report. [PDF]
Catana AC +9 more
europepmc +1 more source
TNF and type I interferon crosstalk controls the fate and function of plasmacytoid dendritic cells. [PDF]
Arroyo Hornero R +7 more
europepmc +1 more source
EP300-mediated lactylation leads to ulcerative colitis via CD86-positive plasmacytoid dendritic cells: A Mendelian randomization and mediation analysis. [PDF]
Cao X +5 more
europepmc +1 more source

