Results 21 to 30 of about 5,522 (198)
Plasmalogens and Chronic Inflammatory Diseases [PDF]
Frontiers in Physiology, 2021 It is becoming widely acknowledged that lipids play key roles in cellular function, regulating a variety of biological processes. Lately, a subclass of glycerophospholipids, namely plasmalogens, has received increased attention due to their association ...
José Carlos Bozelli +2 more
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Plasmalogen biosynthesis in peroxisomal disorders: fatty alcohol versus alkylglycerol precursors.
Journal of Lipid Research, 1988 In recent years a growing number of inherited diseases have been recognized to originate from an impairment in one or more peroxisomal functions. Since it is well established that the first two steps in the biosynthesis of plasmalogens proceed in ...
G Schrakamp +5 more
doaj +2 more sources
Analytical Methods for Plasmalogen [PDF]
, 2021 プラスマローゲンはリン脂質のサブクラスの一種で，嫌気性微生物から哺乳類まで生物界に広く分布している。プラスマローゲンの病態生理学的役割はよくわかっていないが，以前から，アルツハイマー病をはじめとする多くの神経変性疾患との関係が示されてきた。近年，体内のプラスマローゲンの変動が，酸化ストレスや慢性炎症を伴う代謝性疾患に関与するという多くの報告があり，血漿・血清中のプラスマローゲンは，これらの疾患のバイオマーカーとして期待される。そこで本稿ではプラスマローゲンの疾病との関係 ...
西向, めぐみ +2 more
core +2 more sources
Disease Models & Mechanisms, 2020 Rhizomelic chondrodysplasia punctata (RCDP) is a rare genetic disorder caused by mutations in peroxisomal genes essential for plasmalogen biosynthesis.
Wedad Fallatah +6 more
doaj +1 more source
Biomolecules, 2023 Plasmalogens are membrane phospholipids with two fatty acid hydrocarbon chains linked to L-glycerol, one containing a characteristic cis-vinyl ether function and the other one being a polyunsaturated fatty acid (PUFA) residue linked through an acyl ...
Carla Ferreri +7 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2022 Plasmalogens are a specific glycerophospholipid subtype characterized by a vinyl-ether bound at their sn-1 moiety. Their biosynthesis is initiated in the peroxisome by dihydroxyacetone phosphate-acyltransferase (DHAPAT), which is encoded by the DAPAT ...
Rémi Karadayi +16 more
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Plasmalogen composition of Anaeroplasma [PDF]
Journal of Bacteriology, 1975 The polar lipids of Anaeroplasma contained 33.1 percent alk-1'-enyl glyceryl ether (plasmalogen) form. Phosphatidylglycerol was the major polar lipid (55.2 percent) and contained nearly all of the plasmalogen. The alk-1'-enyl glyceryl ether form accounted for 58.3 percent of the phosphatidylglycerol.
T A, Langworthy +3 more
openaire +2 more sources
Brain Research Bulletin, 2022 Ether phospholipid compositions are altered in the plasma or brain of patients with brain disorders, such as Alzheimer and Parkinson’s disease, including those with psychiatric disorders like schizophrenia and bipolar disorders.
Jun Udagawa, Kodai Hino
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Plasmalogen loss caused by remodeling deficiency in mitochondria
Life Science Alliance, 2019 31 P NMR unveils cell type–dependent losses of plasmalogen in the chain remodeling–deficient brain, liver, kidney, and lymphoblast in association with aberrant mitochondrial function and morphology. Lipid homeostasis is crucial in human health.
Tomohiro Kimura +7 more
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Frontiers in Cell and Developmental Biology, 2022 Plasmalogens are a specific type of glycerophospholipid found in especially high levels in neuronal membranes. Decreased blood and brain levels of docosahexaenoic acid (DHA) containing plasmalogens are associated with decreased cognition and ...
Dayan B. Goodenowe +9 more
doaj +1 more source