Results 71 to 80 of about 5,522 (198)

Dietary Lipid Intervention in the Prevention of Brain Aging

Engineering
As people live longer, the burden of aging-related brain diseases, especially dementia, is increasing. Brain aging increases the risk of cognitive impairment, which manifests as a progressive loss of neuron function caused by the impairment of synaptic ...
Wei Xiong, Bing Fang, Xiaoyu Wang, Ming Zhang, Min Du, Jiazeng Sun, Juan Chen, Yixuan Li, Changhao Sun, Xingen Lei, Xue Zhang, Fazheng Ren   +11 more
doaj   +1 more source

Hippocampal mediation in the lipid–Alzheimer's disease pathway: A high‐dimensional mediation analysis stratified by APOE and sex

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 3, July/September 2026.
Abstract INTRODUCTION Systemic lipid dysregulation is a modifiable risk factor for Alzheimer's disease (AD), yet the neuroanatomic pathways through which specific lipids influence AD progression remain poorly delineated. We investigated whether brain structure mediates the relationship between plasma lipids and AD progression, and whether this pathway ...
Yunjia Cao, Yuwei Fan, Qingtao Meng, Jiajia Wang, Rui Chen, for the Alzheimer's Disease Neuroimaging Initiative, the Alzheimer's Disease Metabolomics Consortium   +6 more
wiley   +1 more source

Plasmalogen content and distribution in the sarcolemma of cultured neonatal rat [PDF]

, 1988
Phospholipids are believed to play an important role in pathology and physiology of the myocardium. Because of the distinct physico-chemical properties of plasmalogens we studied the plasmalogen content and distribution in the sarcolemma of cultured rat ...
Verkleij, A.J., Roelofsen, B., B. Roelofsen, Post, J.A., Kamp, J.A.F. op de, J.A. Post, A.J. Verkleij, de Kamp, J.A.F.Op, J.A.F.Op de Kamp   +8 more
core   +2 more sources

Plasmalogens and Alzheimer’s disease: a review [PDF]

Lipids in Health and Disease, 2019
Growing evidence suggests that ethanolamine plasmalogens (PlsEtns), a subtype of phospholipids, have a close association with Alzheimer's disease (AD). Decreased levels of PlsEtns have been commonly found in AD patients, and were correlated with cognition deficit and severity of disease.
Xiao Q. Su, Junming Wang, Andrew J. Sinclair   +2 more
openaire   +4 more sources

Updates on Mediterranean diet and health status: active ingredients and pharmacological mechanisms

British Journal of Pharmacology, Volume 183, Issue 13, Page 3484-3502, July 2026.
The Mediterranean diet (MedDiet) is among the most extensively studied dietary patterns and has been consistently associated with reduced risk of all‐cause mortality, cardiovascular disease, metabolic disorders, cognitive decline and several types of cancers.
Lukas Schwingshackl, Jakub Morze, Sabina Wallerer, Georg Hoffmann   +3 more
wiley   +1 more source

Distinct Functions of Acyl/Alkyl Dihydroxyacetonephosphate Reductase in Peroxisomes and Endoplasmic Reticulum

Frontiers in Cell and Developmental Biology, 2020
Plasmalogens are a subclass of ether glycerophospholipids characterized by a vinyl-ether bond at the sn-1 position of the glycerol backbone. Plasmalogen biosynthesis is initiated in peroxisomes.
Masanori Honsho, Megumi Tanaka, Raphael A. Zoeller, Yukio Fujiki   +3 more
doaj   +1 more source

Lipid Dynamics in the Amyloid Cascade Hypothesis: Evaluating the Biological Relevance of In Vitro Models

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
This review reconsiders the amyloid cascade by placing lipid dynamics at its core. It shows that free lipids, governed by critical micellar concentration, act as pathological chaperones that redirect amyloid aggregation toward membrane‐damaging species.
Sofia Serravalle, Fabio Lolicato, Carmelo Tempra, Martina Pannuzzo, Michele F. M. Sciacca, Danilo Milardi, Carmelo La Rosa   +6 more
wiley   +1 more source

Peroxisomal Lipid Metabolism as a Therapeutic Target in Leukemia

Molecular Nutrition &Food Research, Volume 70, Issue 11, 15 June 2026.
Peroxisomes are emerging as key regulators of lipid metabolism in leukemia. Enhanced metabolism of very‐long‐chain fatty acids (VLCFAs) supports leukemia cell survival, redox homeostasis, and therapeutic resistance. Pharmacologic disruption of peroxisomal fatty acid oxidation causes VLCFA accumulation, oxidative stress, and mitochondrial dysfunction ...
Ekaterina N. Parfenova, Paul A. Spagnuolo   +1 more
wiley   +1 more source

Chloroplast glycerolipid metabolism during maintenance and under stress

The Plant Journal, Volume 126, Issue 5, June 2026.
SUMMARY Chloroplasts are the defining organelles in green plant tissues, converting light into chemical energy with the help of an intricate and extensive membrane system, the thylakoids. In the process, they release oxygen and assimilate carbon and other elements into molecules that constitute a plant cell's building blocks.
Yosia Mugume, John E. Froehlich, Christoph Benning   +2 more
wiley   +1 more source

Plasmalogen phospholipid hydrolysis during hypoxic injury of rabbit proximal tubules [PDF]

, 1995
Plasmalogen phospholipid hydrolysis during hypoxic injury of rabbit proximal tubules. We have identified and quantified the major species of arachidonate-containing phospholipids in proximal tubules by high performance liquid chromatographic and gas ...
Creer, Michael H., Portilla, Didier
core   +1 more source