Results 101 to 110 of about 63,107 (284)
Otolaryngology–Head and Neck Surgery, Volume 173, Issue 3, Page 745-753, September 2025.Abstract Objective Evaluate the use of tranexamic acid (TXA) and observation as a management option for pediatric patients presenting with posttonsillectomy hemorrhage (PTH). Study Design Retrospective analysis of a prospectively implemented quality improvement initiative with a historical control comparison group. Setting Tertiary children's hospital.
Laura A. Petrauskas +12 more
wiley +1 more source
Chemical Adjustment of Fibrinolysis
PharmaceuticalsFibrinolysis is the process of the fibrin–platelet clot dissolution initiated after bleeding has been stopped. It is regulated by a cascade of proteolytic enzymes with plasmin at its core.
Alexey M. Shibeko +4 more
doaj +1 more source
The In Vitro Effects of Pentamidine Isethionate on Coagulation and Fibrinolysis
Molecules, 2019 Pentamidine is bis-oxybenzamidine-based antiprotozoal drug. The parenteral use of pentamidine appears to affect the processes of blood coagulation and/or fibrinolysis resulting in rare but potentially life-threatening blood clot formation.
Rami A. Al-Horani +2 more
doaj +1 more source
Journal of Peptide Science, Volume 31, Issue 9, September 2025.The introduction of an isopeptide bond at the lysine residues in the backbone of Esc(1‐21) led to the generation of five analogs. Among these, Esc(1‐21)ε20 showed the most promising features, having antimicrobial activity comparable with those of the parent peptide, a lower cytotoxicity, and a higher stability to proteolytic degradation.
Bruno Casciaro +11 more
wiley +1 more source
Journal of Cosmetic Dermatology, Volume 24, Issue 9, September 2025.ABSTRACT Background Melasma is a prevalent skin condition that primarily affects females of reproductive age. Despite the various available treatments, managing melasma is challenging due to frequent relapses and partial responses. Tranexamic acid (TXA) has gained attention as a potential treatment because of its antifibrinolytic and anti‐melanogenic ...
Behrooz Heidary +4 more
wiley +1 more source
Studies on the Mechanism of Inactivation of Human Complement by Plasmin and by Antigen-Antibody Aggregates [PDF]
, 1955 Irwin H. Lepow +2 more
openalex +1 more source
Photodermatology, Photoimmunology &Photomedicine, Volume 41, Issue 5, September 2025.ABSTRACT Background Narrowband‐ultraviolet B (NB‐UVB) phototherapy is an effective treatment for psoriasis in patients who have failed topical regimens or those who desire to avoid systemic treatment. Despite its regular use in non‐white individuals, NB‐UVB treatment response for psoriasis in skin of color (SOC) has not been systematically reviewed ...
Megan Hauptman +3 more
wiley +1 more source
Tranexamic Acid Improves Memory and Learning Abilities in Aging Mice
Journal of Experimental Pharmacology, 2020 Keiichi Hiramoto,1 Yurika Yamate,1 Kazunari Matsuda,2 Daijiro Sugiyama,2 Yasutaka Iizuka2 1Department of Pharmaceutical Sciences, Suzuka University of Medical Science, Suzuka, Mie 513-8670, Japan; 2R&D Department, Daiichi Sankyo Healthcare Co., LTD ...
Hiramoto K +4 more
doaj
Activation of Plasminogen by Trypsin and Plasmin [PDF]
, 1952 Walter Kocholaty +2 more
openalex +1 more source
Skin Research and Technology, Volume 31, Issue 9, September 2025.ABSTRACT Purpose This study investigated the enhanced skin permeation and pigmentation reduction effects of an ion‐pair complex formed between tranexamic acid (TXA) and mandelic acid (MA). The TXA‐MA complex demonstrated superior skin permeability and greater inhibition of cytokine expression compared to TXA alone, ultimately proving more effective in ...
Hyungjoon Jeon +9 more
wiley +1 more source