Results 201 to 210 of about 315,782 (393)

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma

The FEBS Journal, EarlyView.
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris, Paraskevi Ioannou, Nikolaos A. Afratis   +2 more
wiley   +1 more source

Transcranial Histotripsy Clot and Tissue Ablation for Intracerebral Hemorrhage Evacuation and Other Brain Applications

, 2023
STROKE: Vascular and Interventional Neurology, EarlyView.
Jonathan Sukovich, Zhen Xu, Aditya S. Pandey   +2 more
wiley   +1 more source

Fresh frozen plasma therapy in type I plasminogen deficiency: a case of ligneous conjunctivitis with hydrocephalus. [PDF]

Oxf Med Case Reports
AboGhayyada I, Zeidan M, Makhlouf TZ, AbuGhiyatha A, Ghnimat M, Najajreh M.   +5 more
europepmc   +1 more source

Role of leukocytes in hemostasis during orthotopic liver transplantation [PDF]

, 1993
Bechstein, W. O., Himmelreich, G., Huhn, D., Jochum, Marianne, Machleidt, W., Muser, M., Neuhaus, P., Riess, H., Roissaint, R.   +8 more
core   +1 more source

The influence of dehydration on the prognosis of acute ischemic stroke for patients treated with tissue plasminogen activator [PDF]

, 2017
Fei-Fan Wu, Yen-Chu Hung, Yuan‐Hsiung Tsai, Jen‐Tsung Yang, Tsong‐Hai Lee, Chia-Wei Liow, Jiann-Der Lee, Chung-Jen Lin, Tsung‐I Peng, Leng-Chieh Lin   +9 more
openalex   +1 more source

Acceptability and Determinants for Implementation of the EnzySystem, a Novel Near‐Patient Testing Platform for Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Coagulation testing in haemophilia A is limited by the scarcity of testing facilities capable of performing relevant assays. This issue incentivized the development of the EnzySystem for haemophilia A, a near‐patient testing platform aimed to measure Factor VIII activity and thrombin generation simultaneously within 1 h from 100 ...
Aernoud P. Bavinck, Kyle Davis, Lisa van Engelshoven, Monique G. van Lier, Tanja Hamacher, Nicole M. A. Blijlevens, Amy Shapiro, Saskia E. M. Schols, Waander L. van Heerde   +8 more
wiley   +1 more source

uPA-mediated remodeling of CCL21 gradients regulates lymphatic migration of dendritic cells. [PDF]

J Cell Biol
Collado-Diaz V, Christakopoulou MN, Schineis P, Blatter K, Laubender D, Trzebanski S, Thoma M, Gadient Y, Tatliadim H, Gkelis K, Friess MC, Purvanov V, Samson GPB, Artinger M, Bisoendial R, Yepes M, de Veer SJ, Craik D, Behrendt N, Silina K, Legler DF, Halin C.   +21 more
europepmc   +1 more source

Image 3_Urokinase-type plasminogen activator deficiency enhances CD8+ T cell infiltration and anti-PD-1 therapy efficacy in prostate cancer.tif

Xiaoyi Li (669720), Xiao Zhang (152326), Xing Fu (42224), Hong Wu (105254), Xinyu Ye (401069), Xin Huang (11077), Yuhao Cui (22152538), Chao-Nan Qian (248097), Yi Lu (6211), Jian Zhang (1682)   +9 more
openalex   +1 more source

P1.03D.11 Association Between Plasminogen Activator Inhibitor-1 & Tolerance Against Anti-PD-1 Antibody in Non-Small Cell Lung Cancer [PDF]

Masaharu Sumii, T. Masuda, Keigo Shimoji, Kosuke Yamaguchi, S. Sakamoto, Yasushi Horimasu, Toshiyuki NAKASHIMA, Hiroko Iwamoto, Hiromi Hamada, N. Hattori   +9 more
openalex   +1 more source