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Plasminogen Receptors and Fibrinolysis [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
The ability of cells to promote plasminogen activation on their surfaces is now well recognized, and several distinct cell surface proteins have been demonstrated to function as plasminogen receptors. Here, we review studies demonstrating that plasminogen bound to cells, in addition to plasminogen directly bound to fibrin, plays a major role in ...
Lindsey A Miles   +2 more
exaly   +4 more sources
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Interaction of heparin with plasminogen activators and plasminogen: effects on the activation of plasminogen

Biochemistry, 1986
The amidolytic plasmin activity of a mixture of tissue plasminogen activator (tPA) and plasminogen is enhanced by heparin at therapeutic concentrations. Heparin also increases the activity in mixtures of urokinase-type plasminogen activator (uPA) and plasminogen but has no effect on streptokinase or plasmin. Direct analyses of plasminogen activation by
P, Andrade-Gordon, S, Strickland
openaire   +2 more sources

Plasminogen deficiency [PDF]

open access: yesHaemophilia, 2008
Summary.  Plasminogen deficiency has emerged as a well‐recognized disorder in which reduced levels of plasminogen lead to the development of pseudo membranes on mucosal surfaces, with subsequent end‐organ damage of the affected tissue. Ligneous conjunctivitis is the most recognizable, well‐documented, and common presentation of the clinical syndromes ...
R, Mehta, A D, Shapiro
exaly   +3 more sources

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