Results 31 to 40 of about 190,587 (365)

Structural basis for the pathophysiology of lipoprotein(a) in the athero-thrombotic process

Brazilian Journal of Medical and Biological Research, 1997
Lipoprotein Lp(a) is a major and independent genetic risk factor for atherosclerosis and cardiovascular disease. The essential difference between Lp(a) and low density lipoproteins (LDL) is apolipoprotein apo(a), a glycoprotein structurally similar to ...
E. Anglés-Cano
doaj   +1 more source

A critical role for plasminogen in inflammation

Journal of Experimental Medicine, 2020
Plasminogen, primarily a blood protein involved in fibrinolysis, also participates in inflammatory processes throughout the body. Baker and Strickland summarize the role of plasminogen and its activator system in regulating inflammation in health and ...
S. K. Baker, S. Strickland
semanticscholar   +1 more source

Neuroimaging for differential diagnosis of transient neurological attacks

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Background Rapid yet comprehensive neuroimaging protocols are required for patients with suspected acute stroke. However, stroke mimics can account for approximately one in five clinically diagnosed acute ischemic strokes and the rate of thrombolyzed mimics can be as high as 17%.
Ying Wang, Hao Zha
wiley   +1 more source

DnaK Functions as a Moonlighting Protein on the Surface of Mycoplasma hyorhinis Cells

Frontiers in Microbiology, 2022
Mycoplasma hyorhinis is a common pathogen of swine and is also associated with various human tumors. It causes systemic inflammation, typically polyserositis and polyarthritis, in some infected pigs. However, the pathogenic mechanism of M.
Yao Li, Yao Li, Jia Wang, Jia Wang, Beibei Liu, Yanfei Yu, Yanfei Yu, Yanfei Yu, Ting Yuan, Yanna Wei, Yanna Wei, Yuan Gan, Jia Shao, Jia Shao, Guoqing Shao, Guoqing Shao, Guoqing Shao, Guoqing Shao, Zhixin Feng, Zhixin Feng, Zhixin Feng, Zhigang Tu, Qiyan Xiong, Qiyan Xiong, Qiyan Xiong, Qiyan Xiong   +25 more
doaj   +1 more source

Plasminogen improves lung lesions and hypoxemia in patients with COVID-19

QJM : monthly journal of the Association of Physicians, 2020
Background Lungs from patients with coronavirus disease 2019 (COVID-19) have shown typical signs of acute respiratory distress syndrome (ARDS), formation of hyaline membrane mainly composed of fibrin and ‘ground-glass’ opacity.
Yuanyuan Wu, Ting Wang, Chunying Guo, Dongmei Zhang, Xiaojing Ge, Zhaoxing Huang, Xianshan Zhou, Yinping Li, Qingzhen Peng, Jinan Li   +9 more
semanticscholar   +1 more source

S100A10, a novel biomarker in pancreatic ductal adenocarcinoma

Molecular Oncology, 2018
Pancreatic cancer is arguably the deadliest cancer type. The efficacy of current therapies is often hindered by the inability to predict patient outcome.
Moamen Bydoun, Andra Sterea, Henry Liptay, Andrea Uzans, Weei‐Yuarn Huang, Gloria J. Rodrigues, Ian C.G. Weaver, Hong Gu, David M. Waisman   +8 more
doaj   +1 more source

The Complement Binding and Inhibitory Protein CbiA of Borrelia miyamotoi Degrades Extracellular Matrix Components by Interacting with Plasmin(ogen)

Frontiers in Cellular and Infection Microbiology, 2018
The emerging relapsing fever spirochete Borrelia (B.) miyamotoi is transmitted by ixodid ticks and causes the so-called hard tick-borne relapsing fever or B. miyamotoi disease (BMD).
Ngoc T. T. Nguyen, Florian Röttgerding, Gayatri Devraj, Yi-Pin Lin, Arno Koenigs, Arno Koenigs, Peter Kraiczy   +6 more
doaj   +1 more source

Efficacy and safety of rivaroxaban versus placebo after lower extremity bypass surgery: A post hoc analysis of a “CASPAR like” outcome from VOYAGER PAD

Clinical Cardiology, Volume 45, Issue 12, Page 1143-1146, December 2022., 2022
Abstract Background The Clopidogrel and Acetylsalicylic Acid in Bypass Surgery for Peripheral Arterial Disease (CASPAR) trial is the only large, double‐blind, placebo‐controlled trial of dual antiplatelet therapy (DAPT) versus aspirin in patients with peripheral artery disease (PAD) after lower extremity revascularization (LER).
Marc P. Bonaca, Michael Szarek, E. Sebastian Debus, Mark R. Nehler, Manesh R. Patel, Sonia S. Anand, Eva Muehlhofer, Scott D. Berkowitz, Lloyd P. Haskell, Rupert M. Bauersachs   +9 more
wiley   +1 more source

Featured Species-Specific Loops Are Found in the Crystal Structure of Mhp Eno, a Cell Surface Adhesin From Mycoplasma hyopneumoniae

Frontiers in Cellular and Infection Microbiology, 2019
Enolase is an evolutionarily conserved enzyme involved in the processes of glycolysis and gluconeogenesis. Mycoplasma hyopneumoniae belongs to Mycoplasma, whose species are wall-less and among the smallest self-replicating bacteria, and is an important ...
Rong Chen, Yanfei Yu, Zhixin Feng, Rong Gan, Xing Xie, Zhenzhen Zhang, Qingyun Xie, Weiwu Wang, Tingting Ran, Wei Zhang, Qiyan Xiong, Qiyan Xiong, Guoqing Shao, Guoqing Shao   +13 more
doaj   +1 more source

Development and application of global assays of hyper‐ and hypofibrinolysis

Research and Practice in Thrombosis and Haemostasis, 2020
Numerous methods for evaluation of global fibrinolytic activity in whole blood or plasma have been proposed, with the majority based on tissue‐type plasminogen activator (t‐PA) addition to initiate fibrinolysis. We propose that such an approach is useful
Anton Ilich, Denis F. Noubouossie, Michael Henderson, Patrick Ellsworth, Kathleen F. Molitor, Elena Campello, Shannon Meeks, Amy Dunn, Myung S. Park, Rafal Pawlinski, Paolo Simioni, Amy Shapiro, Nigel S. Key   +12 more
doaj   +1 more source