Results 141 to 150 of about 3,389,488 (311)

Elucidating the Role and Mechanism of Alpha‐Enolase in Senescent Amelioration via Metabolic Reprogramming

Cell Proliferation, EarlyView.
KB2764 interacted with alpha‐enolase (ENO1) and pyruvate kinase M (PKM), ultimately leading to PKM phosphorylation of ENO1. KB2764 consequently increased mitochondrial ATP production and decreased glycolysis dependence. Furthermore, the action of KB2764 extends its application to extend the lifespan of Caenorhabditis elegans.
Yun Haeng Lee, Hyunwoong Lim, Gyungmin Kim, Geonhee Jang, Myeong Uk Kuk, Ji Ho Park, Jee hee Yoon, Yoo Jin Lee, Duyeol Kim, Byeonghyeon So, Minseon Kim, Hyung Wook Kwon, Youngjoo Byun, Joon Tae Park   +13 more
wiley   +1 more source

Urokinase-type Plasminogen Activator and Plasminogen Activator Inhibitor Induction by Etoposide in a Glioblastoma Cell Strain

Food Technology and Biotechnology, 2002
Urokinase plasminogen activator (uPA) and its inhibitors (PAI) are elements of plasminogen activation system, a proteolytic system involved in many physiological and patological processes.
Branko Brdar, Maja Matulić
doaj  

The Active Site of Bovine Plasminogen Activator

, 1968
Louis Summaria, Chung‐Mei Ling, William R. Groskopf, Kenneth C. Robbins   +3 more
openalex   +1 more source

Deciphering Age‐Dependent ECM Remodelling in Liver: Proteomic Profiling and Its Implications for Aging and Therapeutic Targets

Cell Proliferation, EarlyView.
This study reveals age‐dependent remodelling of the liver extracellular matrix (ECM), identifying Lumican as a key regulator of hepatocyte proliferation and stemness in foetal development. Dynamic ECM shifts influence liver function, offering insights into therapeutic strategies for aging‐related hepatic decline.
Juan Liu, Qingru Song, Chen Li, Jiexin Yan, Ni An, Wenzhen Yin, Jinmei Diao, Yuxin Su, Yunfang Wang   +8 more
wiley   +1 more source

Transcranial Histotripsy Clot and Tissue Ablation for Intracerebral Hemorrhage Evacuation and Other Brain Applications

, 2023
STROKE: Vascular and Interventional Neurology, EarlyView.
Jonathan Sukovich, Zhen Xu, Aditya S. Pandey   +2 more
wiley   +1 more source

Bacille Calmette-Guérin infection in the mouse. Regulation of macrophage plasminogen activator by T lymphocytes and specific antigen. [PDF]

, 1978
Siamon Gordon, Zanvil A. Cohn
openalex   +1 more source

Medical countermeasures during public health emergencies—Does information sharing among health system coalition help?

Decision Sciences, EarlyView.
Abstract Challenged by constrained healthcare resources, hospitals encounter barriers to accommodating patient demand during public health emergencies. Building on a comprehensive literature review of information and knowledge exchange in healthcare, disaster management, and humanitarian operations management, this study explores the influence of ...
Sukrit Pal, Anand Nair
wiley   +1 more source

Direct binding of Smad3 and Smad4 to critical TGFβ‐inducible elements in the promoter of human plasminogen activator inhibitor‐type 1 gene

EMBO Journal, 1998
S. Dennler, S. Itoh, D. Vivien, P. ten Dijke, S. Huet, J. Gauthier   +5 more
semanticscholar   +1 more source

Recurrent hypoglycemia exposure increases the risk of platelet activation and thrombosis in insulin‐treated diabetic rats

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Diabetes is a widespread disease associated with long‐term complications. Treatment of diabetes alleviates these complications but cause an increased risk of recurrent hypoglycemia (RH). Hypoglycemia exposure increases the risk of cardiovascular events by an unknown mechanism.
Ashish K. Rehni, Sunjoo Cho, Allen Liu, Jonathan Lo, Stephanie S. Kim, Nathalie Khoury, Miguel A. Perez‐Pinzon, Wenche Jy, Kunjan R. Dave   +8 more
wiley   +1 more source

56. Experimental Study of Surgical Procedure upon Plasminogen Activator and Inhibitor in Brain Tissue of Subcellular Units and in Blood

, 1966
Yoshihiro Okada
openalex   +2 more sources