Results 141 to 150 of about 200,214 (356)
Granulocyte Transfusions in Pediatric Hemato‐Oncology: Neutrophil Response and CRP Kinetics
ABSTRACT Background Granulocyte transfusions (GTXs) are used in neutropenic pediatric hemato‐oncology patients with infections unresponsive to antimicrobial therapy, but their clinical benefit remains uncertain. Methods We retrospectively reviewed all pediatric patients who received GTXs between 2013 and 2023 at a tertiary medical center.
Aviv Sever+9 more
wiley +1 more source
Clinical periodontal diagnosis
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi+5 more
wiley +1 more source
The resistance of fibrinogen and soluble fibrin monomer in blood to degradation by a potent plasminogen activator derived from cadaver limbs [PDF]
Victor Gurewich, E Hyde, B Lipinski
openalex +1 more source
Insights Into Effects of Natural Bioactive Components on Inflammatory Diseases in Respiratory Tract
ABSTRACT The increasing prevalence of inflammatory diseases in the respiratory tract worldwide has raised concerns, and due to its high prevalence and poor prognosis, it remains a clinical focus and research hotspot. These inflammatory diseases include airway inflammation, asthma, bacterial antigens‐induced tonsil epithelial inflammation, chronic ...
Jincan Luo+4 more
wiley +1 more source
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple+4 more
wiley +1 more source
Harnessing synthetic key receptor modulators, this study presents a breakthrough in Wnt/β‐catenin regulation. The FZD agonist RRP‐pbFn bypasses LRP5/6 to drive organoid expansion and tissue regeneration, while the LRP antagonist RRP‐Dkk1c eradicates tumors. These tools enable precise pathway control, advancing regenerative and cancer therapies.
Quanhui Dai+9 more
wiley +1 more source
Brain metastasis in non‐small cell lung cancer: High‐risk factors and predictive models
Artificial intelligence (AI) can integrate of data to predict brain metastases (BM) in non‐small cell lung cancer (NSCLC). AI algorithms are employed to analyze these multifaceted datasets, enabling the identification of complex patterns and correlations that may not be apparent through traditional analytical methods.
Chen Gong+7 more
wiley +1 more source
The Active Site of Bovine Plasminogen Activator
Louis Summaria+3 more
openalex +1 more source
Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology+4 more
wiley +1 more source