Results 201 to 210 of about 241,486 (290)

Proteomics-Based Soluble Urokinase Plasminogen Activator Receptor Levels Are Associated With Adverse Cardiovascular Outcomes in the General Population: Insights From the UK Biobank. [PDF]

J Am Heart Assoc
Sakr SM, Medina-Inojosa JR, Liu C, Chuckaree ID, Agusala V, Lodhi R, Mecklai Z, Owais M, Al Kasem M, Hritani W, Hasan M, Hayek S, Sun YV, Quyyumi AA.   +13 more
europepmc   +1 more source

Elevated Lipoprotein(a) Predicts Recurrent Myocardial Infarction in Diabetic Patients Following Acute Coronary Syndromes

Clinical Cardiology, Volume 49, Issue 11, November 2026.
Elevated lipoprotein(a) levels are associated with an increased risk of recurrent myocardial infarction in diabetic patients following acute coronary syndromes or PCI, but not with repeat revascularization. These findings highlight Lp(a) as a key contributor to residual cardiovascular risk and a potential tool for post‐ACS risk stratification. ABSTRACT
Ermilo Echeverria‐Ortegon, Mario César Torres‐Chávez, Alfredo Pérez‐Tagle Tejeda, Paulina Caballero‐Osorno, Juan Pastor‐Cervantes, Hugo Laviada‐Molina   +5 more
wiley   +1 more source

COMPARABLE RESULTS OF SUBRETINAL INJECTION AND INTRAVITREAL INJECTION OF TISSUE PLASMINOGEN ACTIVATOR IN THE TREATMENT OF SUBMACULAR HEMORRHAGE: A Meta-Analysis of Efficacy. [PDF]

Retina
Zhang L, Zhang Y, Si W, Wang X, Jiang S, Qin X.   +5 more
europepmc   +1 more source

Proteomic signatures of equine dental tooth tissues in ageing and disease

Equine Veterinary Journal, Volume 58, Issue 6, Page 1552-1569, November 2026.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen, Danae Emilie Zambouli, Iris Gringel, Zoe Nugent, Kazuhiro Yamamoto, Lee Cooper, Andrew J. Peffers, Guido Rocchigiani, Mandy J. Peffers   +8 more
wiley   +1 more source

Plasminogen Activator Inhibitor-1 is Internalized by Endothelial Cells via A Pinocytosis-Like Mechanism and Evades Degradation. [PDF]

FASEB J
McAdow M, Ahmetaj G, Hauschel R, Eichmann A, Sessa W.   +4 more
europepmc   +1 more source

Revisiting Inherited Metabolic Diseases (IMDs) Through the Lens of Selective Autophagy

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Selective autophagy is increasingly recognized as a fundamental quality‐control mechanism that complements bulk autophagy by enabling the targeted degradation of specific intracellular cargos, including mitochondria, endoplasmic reticulum (ER), lipid droplets, glycogen, peroxisomes, ferritin, ribosomes, and protein aggregates.
Marianna Maddaluno, Laura Cinque, Viviana Cetrangolo, Chiara De Leonibus   +3 more
wiley   +1 more source

Thermodynamics and selection of the plasminogen activator inhibitor-1 latency transition. [PDF]

J Biol Chem
Haynes LM, Holding ML, Woodard J, Siemieniak D, Ginsburg D.   +4 more
europepmc   +1 more source

Leptin Neutralization Attenuates Inflammaging in Endothelial and Immune Cell Models

MedComm, Volume 7, Issue 11, November 2026.
Multiple mechanisms including senescent cell accumulation, metabolic and endotoxin‐driven stimulation of immune and endothelial cells contribute to inflammaging, the chronic low‐grade inflammatory status underlying age‐related diseases. Blocking leptin signaling in experimental models of inflammaging blunts inflammation in a model‐specific manner while
Valeria Pellegrini, Rosalba La Grotta, Alessia Metallo, Francesca Carreras, Chiara Frigé, Giulia Matacchione, Angelica Giuliani, Jacopo Sabbatinelli, Fabiola Olivieri, Francesca Rispoli, Lorenzo Drago, Cesare Celeste Berra, Raffaele Marfella, Giuseppe Paolisso, Giuseppe Matarese, Claudio Procaccini, Ilaria Spatocco, Giorgia Mele, Paola de Candia, Antonio Ceriello, Francesco Prattichizzo   +20 more
wiley   +1 more source

Evaluation of Serum Soluble Urokinase Plasminogen Activator Receptor (suPAR) Levels in Different Metabolic Obesity Phenotypes and Their Association with Inflammatory Cytokines: A Cross-Sectional Study. [PDF]

J Clin Med
Acet A, Ozdemir C, Solak H.
europepmc   +1 more source