Results 221 to 230 of about 3,602,430 (295)

Targeting autophagy and plasminogen activator inhibitor-1 increases survival and remodels the tumor microenvironment in glioblastoma. [PDF]

J Exp Clin Cancer Res
Shifman SG, O'Connor JL, Radin DP, Sharma A, Infante L, Ferraresso F, Kastrup CJ, Lawrence DA, Tsirka SE.   +8 more
europepmc   +1 more source

Hepatic AhR Activation by TCDD Induces Obesity and Steatosis via Hepatic Plasminogen Activator Inhibitor-1 (PAI-1). [PDF]

Int J Mol Sci
Oh SJ, Im S, Kang S, Lee AG, Lee BC, Pak YK.   +5 more
europepmc   +1 more source

Imaging efficacy and safety of low dose intraventricular tissue plasminogen activator in aneurysmal subarachnoid hemorrhage: case series. [PDF]

Acta Neurochir (Wien)
Liu C, Wroe WW, Zeineddine HA, Dawes B, Giordano M, McCabe A, Chen CJ, McBride DW, Gusdon AM, Choi HA, Blackburn SL.   +10 more
europepmc   +1 more source

The effect of adipokines in HIV associated pre-eclampsia : (C-peptide, ghrelin, gastric inhibitory polypeptide, glucagon like peptide-1, glucagon, insulin plasminogen activator inhibitor-1 and visfatin).

, 2016
Colisile N. Mathonsi
openalex   +1 more source

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Tissue Plasminogen Activator

New England Journal of Medicine, 1988
TISSUE plasminogen activator (t-PA) is a naturally occurring protein that catalyzes the conversion of the inactive proenzyme plasminogen into the active serine protease plasmin.
John A. Oates, Alastair J.J. Wood, Joseph Loscalzo, Eugene Braunwald   +3 more
openaire   +2 more sources

Mechanisms of Plasminogen Activation by Mammalian Plasminogen Activators

Enzyme, 1988
Plasminogen activators convert the proenzyme plasminogen to the active serine protease plasmin by hydrolysis of the Arg560-Val561 peptide bond. Physiological plasminogen activation is however regulated by several additional molecular interactions resulting in fibrin-specific clot lysis.
H R, Lijnen, D, Collen
openaire   +2 more sources

Plasminogen activator inhibitors

Trends in Cardiovascular Medicine, 1991
Plasminogen activator inhibitors (PAIs) regulate plasminogen activation in normal and pathologic processes. Plasminogen activator inhibitor 1 (PAI-1) is the major physiologic inhibitor of both tissue-type and urokinase-type plasminogen activators. It is a highly regulated single-chain glycoprotein, whose overexpression in vivo impairs the fibrinolytic ...
J, Schneiderman, D J, Loskutoff
openaire   +2 more sources

Glycated Proteins Modulate Tissue–Plasminogen Activator-Catalyzed Plasminogen Activation

Biochemical and Biophysical Research Communications, 1997
Plasminogen activation by tissue-plasminogen activator (t-PA) is accelerated by the presence of a macromolecular surface, which acts as a template that brings enzyme and substrate in close proximity. Modification of lysine residues, which are important for this template function, occurs in diabetic patients as a consequence of glycation of proteins. In
I W, Bobbink, W L, Tekelenburg, J J, Sixma, H C, de Boer, J D, Banga, P G, de Groot   +5 more
openaire   +2 more sources

Plasminogen Activator and Plasminogen Activator Inhibitor Activities in a Reference Population

American Journal of Clinical Pathology, 1988
The influence of age, gender, and aspirin ingestion on plasma levels of tissue plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) activities was studied in a reference population of 35 men and 35 women between the ages of 20 and 65 years.
C, Krishnamurti, D B, Tang, C F, Barr, B M, Alving   +3 more
openaire   +2 more sources