Results 241 to 250 of about 3,389,488 (311)

Inflammation in atherosclerotic cardiovascular disease: From diagnosis to treatment

European Journal of Clinical Investigation, Volume 55, Issue 7, July 2025.
Inflammation in atherosclerotic cardiovascular disease. Residual inflammatory risk (RIR), defined by high‐sensitive C‐reactive protein (hsCRP) concentration of ≥2 mg/L, represents a strong predictor of future atherosclerotic cardiovascular disease (ASCVD) events. Although increased hsCRP values ≥2 mg/L might be detected in every three out of five ASCVD
Natalie Arnold, Wolfgang Koenig
wiley   +1 more source

Evaluation of Soluble Urokinase Plasminogen Activator Receptor in COVID-19 Patients. [PDF]

J Clin Med
Arientová S, Matúšková K, Bartoš O, Beran O, Holub M.   +4 more
europepmc   +1 more source

Identification of a Novel Mutation in the SERPINE1 Gene Causing Clinical Hyperfibrinolysis in English Springer Spaniel Dogs

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Background A 7‐month‐old female spayed English Springer Spaniel (ESS) was evaluated for spontaneous hemoperitoneum. Hyperfibrinolysis was identified on thromboelastography. Hypothesis/Objectives To identify a genetic mutation causing congenital hyperfibrinolysis in the proband and evaluate the prevalence of the mutation in the ESS breed ...
Kelley Kilpatrick, Jonah N. Cullen, Farah F. Almeer, LeeAnn Higgins, Todd Markowski, Marjory Brooks, Steven G. Friedenberg, Molly Racette   +7 more
wiley   +1 more source

Proteomics-Based Soluble Urokinase Plasminogen Activator Receptor Levels Are Associated With Incident Heart Failure Risk. [PDF]

JACC Adv
Yadalam AK, Gold ME, Patel KJ, Liu C, Razavi AC, Jain V, Vatsa N, Gold D, Owais M, Haroun N, Sun YV, Quyyumi AA.   +11 more
europepmc   +1 more source

Prognostic Value of the TLM3 Biomarker Panel for Early Fibrosis Development in MASLD Within the General Population

Liver International, Volume 45, Issue 7, July 2025.
ABSTRACT Background & Aims Fibrotic MASLD is associated with increased morbidity and mortality, often remaining asymptomatic until advanced stages of disease. Predicting fibrosis onset and progression would improve risk stratification and treatment allocation.
Koen C. van Son, Jelle C. B. C. de Jong, Serdar Özsezen, Martien P. M. Caspers, Quinten J. J. Augustijn, Jessica Snabel, Henrike Galenkamp, Henrike M. Hamer, Anne‐Marieke van Dijk, Arianne van Koppen, Anne Linde Mak, Bert‐Jan van den Born, Max Nieuwdorp, Joost P. H. Drenth, Lise Lotte Gluud, Maarten E. Tushuizen, Roeland Hanemaaijer, Lars Verschuren, Adriaan G. Holleboom   +18 more
wiley   +1 more source

Dementia with Lewy Bodies (DLB), Parkinson's Disease (PD), and Multiple System Atrophy (MSA) Are Synucleopathies Characterized by Increased Serum Levels of Plasminogen Activator Inhibitor‑1 (PAI-1). [PDF]

ACS Omega
Angelucci F, Nedelska Z, Napravnikova Manová B, Katonová A, Jurášová V, Svetlikova D, Vyhnálek M, Hort J.   +7 more
europepmc   +1 more source

Growth Arrest and DNA Damage Protein 45A Promotes PPRV Replication via the Downregulation of TBK1 Expression to Inhibit IFN‐β Signaling Pathway

The FASEB Journal, Volume 39, Issue 12, 30 June 2025.
A working model of host protein GADD45A regulation of PPRV replication. During PPRV infection, the viral protein V forms a complex with GADD45A in the cytoplasm. GADD45A interacts with TBK1 and inhibits its expression. Similarly, V also interacts with TBK1 and inhibits TBK1 expression.
Haiyan Ding, Wenping Yang, Jinyan Wu, Junhuang Wu, Mengyi Wang, Jijun He, Ligang Yuan, Haixue Zheng, Youjun Shang, Dan Li   +9 more
wiley   +1 more source

Differentiation-responsive elements in the 5' region of the mouse tissue plasminogen activator gene confer two-stage regulation by retinoic acid and cyclic AMP in teratocarcinoma cells.

, 1989
Richard J. Rickles, Andrew L. Darrow, Sidney Strickland   +2 more
openalex   +1 more source

Soluble Urokinase Plasminogen Activator Receptor: A Promising Biomarker for Mortality Prediction Among Critical ED Patients. [PDF]

Int J Mol Sci
Wozniak P, Sieminski M, Pyrzowski J, Petrosjan R, Głogowski-Kulasza J, Leszczyński-Czeczatka J.   +5 more
europepmc   +1 more source

Transcriptomic Differences Between Immortalized Oral and Skin Keratinocytes

The FASEB Journal, Volume 39, Issue 12, 30 June 2025.
To examine the site‐specific differences underlying the wound healing outcomes of skin versus oral wounds, immortalized oral (TIGK) and skin (HaCaT) keratinocytes were examined for functional and transcriptional differences. TIGK have enhanced migration and proliferation.
Chen Han, Yixuan Zhang, Heidi Yuan, Shalyn Keiser, Trevor Leonardo, Lin Chen, Mateusz Wietecha, Luisa A. DiPietro   +7 more
wiley   +1 more source