Results 171 to 180 of about 108,172,160 (276)

Host‐Specific Interactions Between Staphylococcus aureus and Pseudomonas aeruginosa Impair Epithelial Repair in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, Volume 16, Issue 11, Page 1318-1329, November 2026.
ABSTRACT Background Chronic rhinosinusitis (CRS) is frequently associated with polymicrobial biofilms involving Staphylococcus aureus and Pseudomonas aeruginosa. Interactions between these organisms are thought to influence disease severity, but the epithelial effects of exoproteins derived from patient‐matched cocultures remain poorly defined ...
Xiaohan Sun, Mahnaz Ramezanpour, George Bouras, Emma Barry, Alkis J. Psaltis, Peter‐John Wormald, Sarah Vreugde   +6 more
wiley   +1 more source

Placental plasminogen activator inhibitor 1 is induced by platelet-derived TGF-β independently of TGF-β receptor 3 and is upregulated in preeclampsia. [PDF]

Mol Hum Reprod
Forstner D, Kulovic-Sissawo A, Lyssy F, Guettler J, Vejzovic D, Rinner B, Kummer D, Kupper N, Stern C, Gruber M, Neuper L, Daxboeck C, Gupta A, Kohli S, Isermann B, Gauster M.   +15 more
europepmc   +1 more source

Neutrophil Extracellular Traps Block Fibrinolysis in Ischemic Stroke

Annals of Neurology, Volume 100, Issue 5, Page 964-978, November 2026.
Objectives Intravenous thrombolysis (IVT) failure in acute ischemic stroke (AIS) is frequent, but its causes remain elusive. We investigated whether biologically relevant intrathrombus concentrations of tissue plasminogen activator (tPA) were achieved in failed IVT and whether neutrophil extracellular traps (NETs) contributed to this therapeutic ...
Mialitiana Solo Nomenjanahary, Jean‐Philippe Desilles, Fatima Zemali, Astride Perrot, Lucas Di Meglio, Sara Zalghout, Jéromine Fasille, Jérémy Neel, Stéphane Loyau, Julien Labreuche, Marie‐Charlotte Bourrienne, Dorothée Faille, François Delvoye, Véronique Ollivier, Sébastien Dupont, Jasmina Rogozarski, Nahida Brikci‐Nigassa, Robert L. Medcalf, Nadine Ajzenberg, Mikael Mazighi, Benoît Ho‐Tin‐Noé, the compoCLOT Study Group   +21 more
wiley   +1 more source

Advances in the Research of Hypoxia-Inducible Factor-1Alpha and Plasminogen Activator Inhibitor-1 in Vascular-Related Diseases. [PDF]

J Clin Med Res
Xu X, Ge XH.
europepmc   +1 more source

Phytochemical Screening, Pharmacological Evaluation, and Exploratory In Silico Analysis of Emilia sonchifolia Extract and Solvent Fractions

Cell Biochemistry and Function, Volume 44, Issue 11, November 2026.
ABSTRACT Emilia sonchifolia (L.) DC. is a medicinal plant used traditionally for the management of several disorders; however, integrated experimental evaluation of its pharmacological properties remains limited. This study evaluated the phytochemical composition and selected biological activities of the methanolic whole‐plant extract of E. sonchifolia
Md. Masud Morshed, Mohammad Arman, Mohammad Nazmul Islam, Ziaul Karim, Rakibur Rahman, Mohammed Hassan Kawsar, Md. Sohel Rana   +6 more
wiley   +1 more source

Plasminogen activator inhibitor-1, vaspin, and dietary inflammatory index in relation to cardiometabolic health in diabetic women. [PDF]

Front Nutr
Kocabas S, Sanlier N.
europepmc   +1 more source

Elevated Lipoprotein(a) Predicts Recurrent Myocardial Infarction in Diabetic Patients Following Acute Coronary Syndromes

Clinical Cardiology, Volume 49, Issue 11, November 2026.
Elevated lipoprotein(a) levels are associated with an increased risk of recurrent myocardial infarction in diabetic patients following acute coronary syndromes or PCI, but not with repeat revascularization. These findings highlight Lp(a) as a key contributor to residual cardiovascular risk and a potential tool for post‐ACS risk stratification. ABSTRACT
Ermilo Echeverria‐Ortegon, Mario César Torres‐Chávez, Alfredo Pérez‐Tagle Tejeda, Paulina Caballero‐Osorno, Juan Pastor‐Cervantes, Hugo Laviada‐Molina   +5 more
wiley   +1 more source

Proteomic signatures of equine dental tooth tissues in ageing and disease

Equine Veterinary Journal, Volume 58, Issue 6, Page 1552-1569, November 2026.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen, Danae Emilie Zambouli, Iris Gringel, Zoe Nugent, Kazuhiro Yamamoto, Lee Cooper, Andrew J. Peffers, Guido Rocchigiani, Mandy J. Peffers   +8 more
wiley   +1 more source

Fibroblast circSamd4 promotes cardiac fibrosis via activating plasminogen activator inhibitor-1. [PDF]

Redox Biol
Chen Y, Zhang Z, Cheng Y, Chen X, Zhou J, Wei Z, Yao H, Zhang S, Kong Q, Tang H, Wu W, Zhou Z, Tang X, Liu X.   +13 more
europepmc   +1 more source

Revisiting Inherited Metabolic Diseases (IMDs) Through the Lens of Selective Autophagy

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Selective autophagy is increasingly recognized as a fundamental quality‐control mechanism that complements bulk autophagy by enabling the targeted degradation of specific intracellular cargos, including mitochondria, endoplasmic reticulum (ER), lipid droplets, glycogen, peroxisomes, ferritin, ribosomes, and protein aggregates.
Marianna Maddaluno, Laura Cinque, Viviana Cetrangolo, Chiara De Leonibus   +3 more
wiley   +1 more source