Results 131 to 140 of about 58,767 (165)
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Neutralization by Plasminogen Activator Inhibitor-1 of Mutants of Tissue Plasminogen Activator
Enzyme, 1988Deletion mutants of human tissue plasminogen activator (tPA) were expressed in Chinese hamster ovary cells. These cells had been transfected with genes that encoded tPA but included restriction sites that allowed the deletion of DNA encoding specific structural domains of the tPA molecule's heavy chain.
P W, Bergum, L A, Erickson
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Plasminogen activator inhibitor-1 and the kidney
American Journal of Physiology-Renal Physiology, 2002Plasminogen activator inhibitor-1 (PAI-1) is a serine protease inhibitor that was isolated 20 years ago. First recognized as an inhibitor of intravascular fibrinolysis, it is now evident that PAI-1 is a multifunctional protein with actions that may be dependent on or independent of its protease inhibitory effects.
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Plasminogen activator inhibitor 1 in thrombotic disease
Current Opinion in Hematology, 1996Impaired fibrinolytic function, mainly due to an elevation of plasma plasminogen activator inhibitor 1 concentration, is a common finding in patients with thrombotic disease. In patients subjected to hip surgery, preoperatively increased levels of plasminogen activator inhibitor 1 seem to be predictive of postoperative deep venous thrombosis.
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Plasminogen Activator Inhibitor 1 and Atherothrombosis
Thrombosis and Haemostasis, 1993I, Juhan-Vague, M C, Alessi
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Recombinant Plasminogen Activator Inhibitor-1
Drugs of the Future, 1992T.M. Reilly, A.L. Racanelli, S.A. Mousa
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P55. Plasminogen activator inhibitor-1
Blood Coagulation & Fibrinolysis, 1996R. W. Faint +8 more
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Vascular Regulation of Plasminogen Activator Inhibitor-1 Activity
Seminars in Thrombosis and Hemostasis, 1994J M, Edelberg, D C, Sane, S V, Pizzo
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