Results 221 to 230 of about 113,706,673 (279)

Plasminogen activator inhibitor-1 mediates cerebral ischemia-induced astrocytic reactivity. [PDF]

J Cereb Blood Flow Metab
Yanev P, Martin-Jimenez C, Vesga-Jimenez DJ, Zvinys L, Weinrich N, Cree MA, Preuss TM, Zhang X, Yepes M.   +8 more
europepmc   +1 more source

Comment on "Role of increased plasminogen activator inhibitor-1 and vitronectin in gestational diabetes mellitus". [PDF]

Rev Assoc Med Bras (1992)
Yin H, Shi R.
europepmc   +1 more source

Mechanisms behind elevated serum levels of plasminogen activator inhibitor-1 in frontotemporal lobar degeneration. [PDF]

Neural Regen Res
Angelucci F, Hort J.
europepmc   +1 more source

Liver steatosis is positively associated with plasminogen activator inhibitor-1 in apparently healthy individuals with overweight and obesity: A FibroScan-Based Cross-Sectional study. [PDF]

J Transl Med
Lisco G, Guido D, Cerabino N, Di Chito M, Donvito R, Bonfiglio C, Shahini E, Zappimbulso M, Randazzo C, Barletta D, Stabile D, Ancona A, Coletta S, Pesole PL, Giannelli G, De Pergola G.   +15 more
europepmc   +1 more source

Dementia with Lewy Bodies (DLB), Parkinson's Disease (PD), and Multiple System Atrophy (MSA) Are Synucleopathies Characterized by Increased Serum Levels of Plasminogen Activator Inhibitor‑1 (PAI-1). [PDF]

ACS Omega
Angelucci F, Nedelska Z, Napravnikova Manová B, Katonová A, Jurášová V, Svetlikova D, Vyhnálek M, Hort J.   +7 more
europepmc   +1 more source

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Plasminogen Activator Inhibitor-1

Current Medicinal Chemistry, 2004
Plasminogen activator inhibitor-1 (PAI-1) is an important component of the plasminogen/plasmin system as it is the main inhibitor of tissue-type and urokinase-type plasminogen activator. Consequently, PAI-1 plays an important role in cardiovascular diseases (mainly through inhibition of t-PA) and in cell migration and tumor development (mainly through ...
Ann, Gils, Paul J, Declerck
openaire   +2 more sources

Urokinase-type plasminogen activator and its inhibitor plasminogen activator inhibitor-1

Oncology Reports, 1997
Tumor associated proteolysis is an essential mechanism in invasion and metastasis of cancer. The influence of the serine protease urokinase-like plasminogen activator (u-PA) and its inhibitor plasminogen activator inhibitor-1 (PAI-1) on the clinical prognosis of squamous carcinoma of the head and neck region (HNSCC) was evaluated. U-PA and PAI-1 levels
B, Wollenberg, N, Jan, R, Jund, S, Chaubal, M, Untch   +4 more
openaire   +2 more sources

Plasminogen Activator Inhibitor-1 in Aging

Seminars in Thrombosis and Hemostasis, 2014
Plasminogen activator inhibitor-1 (PAI-1), a principal inhibitor of fibrinolysis, is induced in thrombotic, fibrotic, and cardiovascular diseases, which in turn primarily afflict the older population. This induction of PAI-1 may play an important role in the pathology of these diseases as PAI-1 can regulate the dissolution of fibrin and also inhibit ...
Koji, Yamamoto, Kyosuke, Takeshita, Hidehiko, Saito   +2 more
openaire   +2 more sources

Plasminogen Activator Inhibitor-1 and Restenosis

Current Drug Targets, 2007
Despite the introduction of drug-eluting stents restenosis remains an important clinical problem. In this review we examine the role of plasminogen activator inhibitor-1 (PAI-1) in controlling restenosis after balloon angioplasty and stent implantation.
Nadish, Garg, William P, Fay
openaire   +2 more sources