Components of the plasminogen activation system promote engraftment of porous polyethylene biomaterial via common and distinct effects. [PDF]
Rapid fibrovascularization is a prerequisite for successful biomaterial engraftment. In addition to their well-known roles in fibrinolysis, urokinase-type plasminogen activator (uPA) and tissue plasminogen activator (tPA) or their inhibitor plasminogen ...
Christoph A Reichel +8 more
doaj +1 more source
A network analysis to identify pathophysiological pathways distinguishing ischaemic from non-ischaemic heart failure [PDF]
Aims Heart failure (HF) is frequently caused by an ischaemic event (e.g. myocardial infarction) but might also be caused by a primary disease of the myocardium (cardiomyopathy).
Anker, Stefan D. +18 more
core +5 more sources
Decrease of fibrinolytic potential in the occurrence of cerebral ischemia [PDF]
One of the most present clinical manifestations of long and progressive atherothrombotic occurrences is the ischemic cerebrovascular insult, one of the leading causes of death and illness in the world.
Vučković Biljana +4 more
doaj
SOME FIBRINOLYTIC PARAMETERS IN CORONARY ARTERY DISEASE PATIENTS: FOCUS ON UNSTABLE ANGINA SUBGROUPS
Background and aim. Unstable angina is classified into new-onset, progressive, and angina at rest. Though hemostasis plays a crucial role in the pathogenesis of coronary artery disease, including unstable angina, limited data exist regarding ...
Y. V. Tyravska +4 more
doaj +1 more source
Effects of moderate weight loss on anginal symptoms and indices of coagulation and fibrinolysis in overweight patients with angina pectoris [PDF]
Objective: To evaluate the effects of moderate weight loss, in overweight patients with angina, on plasma coagulation, fibrinolytic indicies and pain frequency.
Hankey, C.R. +4 more
core +1 more source
Impaired Fibrinolysis in Pregnancy Failure
Objective: To explore the association between plasma plasminogen activator inhibitor 1 (PAI-1) levels and women experiencing recurrent miscarriages with no live births to those who have had one or more live births.
Samina Mohyuddin +5 more
doaj +3 more sources
Assessment of plasminogen activator inhibitor-1 in obese Egyptian children
Background Plasminogen activator inhibitor-1 (PAI-1) is mainly produced in the liver and in the adipose tissue. Normal fibrin clearance mechanisms were found to be affected by high plasma PAI-1 levels and thus increases risk of thrombosis. The aim of the
Marwa Farouk Mira +3 more
doaj +1 more source
Plasminogen Activator Inhibitor-1 [PDF]
Hypertension is the most common reversible risk factor for stroke, myocardial infarction, and heart failure, affecting >60 million individuals in the United State alone and 1 billion globally.1 According to the World Health Organization, hypertension is now the leading cause of preventable death worldwide.2 Importantly, the prevalence and complications
Daniel I, Simon, Norman M, Simon
openaire +2 more sources
The association of HER2 status with urokinase plasminogen activator (uPA) and plasminogen activator inhibitor 1 (PAI-1) levels raises the question whether uPA/PAI-1 level carries additional clinically relevant prognostic information independently from ...
Dovnik Nina Fokter, Takac Iztok
doaj +1 more source
Data is presented that was utilized as the basis for Bayesian network modeling of influence pathways focusing on the central role of a polymorphism of plasminogen activator inhibitor-2 (PAI-2) on recurrent cardiovascular disease risk in patients with ...
James P. Corsetti +5 more
doaj +1 more source

